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Biomedical subjects

T Toriyama

Publications and source records attributed to T Toriyama.

29 records · Page 2Linked to original sources
PubMed1991

A comparative study of atherosclerosis and osteopenia in elderly and young hemodialysis patients.

The effects of aging on atherosclerosis and osteopenia in hemodialysis patients were investigated. Eighty patients on maintenance hemodialysis were subdivided according to age into old (greater than or equal to 65 years old, N = 40) and young (less than 65 years old, N = 40). Biochemical, radiologic, and biophysical studies were performed in each patient to assess the degree of atherosclerosis and osteopenia. Compared to age-matched controls, patients in the old group exhibited a significantly higher aortic pulse wave velocity (PWV), and old female patients had a significantly lower bone mineral content/bone width (BMC/W). Elderly patients also had a significantly higher aortic PWV and higher grade of aortic calcification as assessed radiologically; in contrast, the BMC/W was lower. Concerning sex differences, elderly male patients had the highest average grade of aortic calcification, the lowest serum Pi, [Ca] x [Pi], and immunoreactive parathyroid hormone concentrations, while elderly female patients had the lowest BMC/W and highest incidence of osteopenia. These observations suggest that elderly male hemodialysis patients are more prone to develop atherosclerosis and elderly female hemodialysis patients to develop advanced osteopenia.

Adult↗
PubMed1991

[A case of disproportionately large communicating fourth ventricle (DLCFV) combined with syringomyelia and Chiari malformation].

We report a rare case of disproportionately large communicating fourth ventricle (DLCFV) combined with syringomyelia and Chiari malformation. The case was a 27-year-old male who underwent ventriculoperitoneal (V-P) shunt on the right side for hydrocephalus caused by traumatic intracerebral and intraventricular hemorrhage. One month later, he became somnolent with posterior fossa symptoms (nausea, vomiting and nystagmus). CT scan demonstrated enlarged fourth ventricle, which was diagnosed as DLCFV because the ventriculogram revealed patency of the aqueduct. One and half month later a second V-P shunt was made on the left side to increase the shunt flow. He became ambulatory with a cane, although the fourth ventricle remained moderately dilated on CT scan. Two months after the additional V-P shunt, he slipped and hit the occiput and immediately became tetraparetic. The patient was treated conservatively under the diagnosis of central spinal cord injury. The MRI taken 2 months after the accident revealed Chiari malformation (type 1), syringomyelia and a dilated fourth ventricle which was compressing the brainstem. After the fourth ventriculoperitoneal (FV-P) shunt, the tetraparesis transiently improved but then again worsened. On the CT scan the syrinx did non change in size, while the size of the fourth ventricle became normal. After syringoperitoneal (S-P) shunt the patient showed a moderate improvement of tetraparesis. Unfortunately he suffered appendicitis complicated with peritonitis and all the shunts were immediately changed to external drainage. However, the patient developed meningitis and became paraplegic. The motor function of the upper extremities slightly improved by aspiration of fluid via the external drainage system from the syrinx.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1990

[Porphyria cutanea tarda in a chronic hemodialysis patient].

After 6 months on hemodialysis, a 58-year-old male patient with diabetes developed photosensitive bullous dermatosis on his hands and face. There was no evidence of liver diseases although the patient had a history of excessive alcohol consumption. He was suspected to have iron overload in the liver. Analysis of porphyrins in plasma, hemofiltrate, urine and feces by high performance liquid chromatography revealed significantly high levels in these samples with a porphyrin profiles which is consistent with porphyria cutanea tarda. The fluorometric assays of plasma also disclosed an elevated plasma porphyrin level. And it seemed that there were correlation between the fluctuation of vesicle formation, serum ferritin level and plasma porphyrin level. Small volume plasma exchange temporarily reduced the plasma porphyrin level and prevented vesicle formation.

Chromatography, High Pressure Liquid↗
PubMed1985

New CT-guided stereotactic apparatus and clinical experience with intracerebral hematomas.

The conventional Sugita stereotactic frame has been improved to perform CT-guided stereotactic surgery both in the CT and operating rooms. The development of our instrument and the software of the scanners' computer are presented. Newly designed equipment produced almost no artifacts on the CT image. Using the improved stereotactic frame, we have operated upon 44 intracerebral hematomas in the CT room. More than 80% of the cases had satisfactory results. Two complications were encountered, and 1 patient died from pneumonia. Our initial experience of the pre- and postoperative cerebral blood flow measurement with 133Xe inhalation method and single photon emission CT is described.

Cerebral Hemorrhage↗
PubMed1984

[Cerebellar hemangioblastoma developing after nephrectomy for renal cell carcinoma].

Cerebellar hemangioblastomas are known to be occasionally associated with abdominal tumors such as renal cyst and renal cell carcinoma. But most of the abdominal tumors reported are clinically silent and usually diagnosed after the hemangioblastomas have been found in the central nervous system. We report a rare case in which a renal cell carcinoma preceeded in its onset of symptoms 4 years to a cerebellar hemangioblastoma. A 56-year-old female underwent left nephrectomy because of a left renal cell carcinoma at the age of 49. About 4 years after the nephrectomy, she developed signs and symptoms of intracranial hypertension and was operated on for a cerebellar tumor which was histologically diagnosed as hemangioblastoma. Her family history was non-contributory. Four years later, recurrence of the cerebellar tumor was found on the CT scan and abdominal studies were negative except for a suspected parapelvic cyst in the right kidney on abdominal ultrasonography. Subtotal removal of the cerebellar hemangioblastoma was performed followed by irradiation.

Carcinoma, Renal Cell↗