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Biomedical subjects

T V Chebotareva

Publications and source records attributed to T V Chebotareva.

5 recordsLinked to original sources

[Large intestine dysbacteriosis and therapy efficacy in patients with respiratory tract tuberculosis in sanatoria].

Long-term chemotherapy of tuberculosis leads to dysbacteriosis of the large intestine, that significantly decreases tolerance of tuberculosis drugs, provokes persistence of tuberculosis intoxication and retards involution of tuberculosis process in the lungs. Recovery of the bifidoflora and lactoflora due to the use of an original sour-milk drink developed by the authors was stated in 65 and 55% of the patients respectively. Moreover, it promoted higher tolerance of the chemotherapeutics since its composition includes amino acids, vitamins B, C, D and E, enzymes and microelements. It should be indicated that the drink was used simultaneously with the chemotherapy and did not require its discontinuation. Therefore, it is recommended that the scheme of the treatment of patients with pulmonary tuberculosis in sanatoria should include corrigating agents and in particular probiotics containing live bifido- and lactobacteria having no contraindications and side effects, and providing elimination of intestinal dysbacteriosis.

Administration, Oral↗

[Efficacy of cow's kumiss in the treatment of large intestine dysbacteriosis and its impact on tolerability of antituberculosis agents in patients with respiratory tract tuberculosis].

Dysbacteriosis of the large intestine is one of severe complications of long-term use of antituberculosis agents in the treatment of respiratory tract tuberculosis that results in a significant decrease of tolerability of antituberculosis agents, persistence of tuberculosis intoxication and slower involution of the tuberculosis process in the lungs. When the complex treatment with antituberculosis agents was accompanied by the use of cow's kumiss for correction of the large intestine dysbacteriosis, the intoxication signs disappeared in 12% of the patients in the main group, while in the patients of the control group the level of the intoxication syndrome increased twice. The rate of the tuberculosis lesions regression evident from the lung roentgenograms was 2.7-fold higher in the main group vs. the control (62 and 23% respectively). The indices of the lung functional capacity recovery in the patients of the main group vs. the control were also higher (41 and 33% respectively). Hepatic toxic reactions in the patients not given cow's kumiss for correction of dysbacteriosis were 8 times more frequent vs. the control. The results of the study made it possible to develop recommendations for phthisiologists in the use of cow's kumiss as one of the methods of pathogenetic therapy in complex treatment of patients with respiratory tract tuberculosis in sanatoria.

Antitubercular Agents↗

[Clinical aspects and treatment of tuberculosis of respiratory organs in adolescents under present epidemiological conditions].

The paper summarizes the results of clinical observations of 55 teenagers suffering from active respiratory tuberculosis. It defines risk factors for this disease in adolescents. Emphasis is laid on the current pathomorphology and a great variety of clinical types of tuberculosis. Treatment of tuberculosis is ascertained to be preferred by using the short-term intensive chemotherapy regimen recommended by the World Health Organization, which is intended to cure most patients in the shortest period as compared with existing routine regimens.

Adolescent↗

[Tuberculosis and maternity].

Tuberculosis during pregnancy is mainly detected by complaints. An infiltrative form of tuberculosis is the most common one in patients of this group. A clinical course of tuberculosis in the pregnant women is accompanied by a profound iron deficiency anemia and develops with higher tuberculin sensitization. As compared with the infants born to mothers who were given antituberculous drugs, these born to mothers with pulmonary tuberculosis not treated during their pregnancy have a lower birthweight. Breast-fed infants born to tuberculosis-affected mothers who were treated during their pregnancy have a higher body weight by their first year than bottle-fed ones and those born to non-treated mothers. Breast milk of mothers with pulmonary tuberculosis contained M. tuberculosis and L-forms but was not a source of infection transmission.

Adult↗