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T V El'chits

Publications and source records attributed to T V El'chits.

11 recordsLinked to original sources
PubMed1987

[Function of the hypophyseal-ovarian-adrenal system in trophoblastic disease].

Hyperproduction of chorionic gonadotropin was shown to be the first link in the chain of hormonal disturbances involved in trophoblastic disease, which induced changes of pituitary gonadotropic function. Ovarian function is affected by disturbances in trophoblastic and pituitary gonadotropic functions and depends on the extension and severity of the disease. This makes a case for corrective hormonal therapy in chorionepithelioma patients resistant to cytostatic or substitution therapy with sex hormones and in whom ovaries have been removed during combined treatment.

Adolescent↗
PubMed1980

[Adrenal cortex function in trophoblastic disease].

In 100 patients with trophoblastic tumors the functional activity of the adrenal cortex was examined before and after chemotherapy. Androgen-producing function of the adrenal cortex was found to be reduced as well as the absolute number of excreted 17-ketosteroids separate fractions and their ratio. The glucocorticoid function of the adrenal cortex shows a monotonous character. Only in patients having uterine chorion-epithelioma with metastases a reliable reduction of the fraction of 11-hydroxy-17-ketosteroids is noted before and after chemotherapy, while the per cent content of free 17-oxy-corticoid fraction is increased with regard to their total amount. Successful chemotherapy, associated with a lower titre of chorionic gonadotropins up to its complete disappearance, does not result in normalization of values characterizing the functional activity of the adrenal cortex.

17-Hydroxycorticosteroids↗
PubMed1977

[Excretion of corticosteroids and catecholamines in cancer of the rectum and stomach].

In patients with cancer of the rectum and stomach the excretion of 17-ketosteroids was reduced, compared with the normal level, most of these patients showing a decreased adrenal glucocorticoid function too. In patients with cancer of the gastrointestinal tract adrenaline and noradrenaline excretion was lower than normal values. There is a distinct correlation between the indices of catecholamines and corticosteroids excretion in the urine of patients with rectal and gastric cancer.

17-Ketosteroids↗