[Changes in the central hemodynamics and kidney activity during the enalapril treatment of hypertension patients].
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Biomedical subjects
Publications and source records attributed to T V Ogneva.
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A study was made of changes of esophageal transport function in 10 patients with thyroid adenoma and in 27 patients after surgical and radiotherapeutic management for thyroid cancer. The results were compared with those of a control group. Significant data on changes on esophageal transport function in patients with thyroid adenoma were unnoticed. Esophageal dysfunction after operation and radioactive iodine therapy for cancer was detected in 55%. Dysfunction was thought to be caused by dysphagia which showed direct correlation with the severity of hypothyroidism.
The results of comparative investigation of 266 cancer patients, 44 patients with benign G. I. tract diseases and 66 healthy subjects using 2 tumor markers (CEA and Ca-19-9) showed the diagnostic value of both methods, not exceeding 38-42%. The most informative were the data on patients with pancreatic and colorectal cancers as well as in patients with detected metastases. Significant differences in the sensitivity, specificity and diagnostic informative value between the two markers were undetectable.
A study of the renal clearance in 37 patients using a Tc nephrotropic agent and a drug 113mIn-pentaind demonstrated coincidence of diagnostic information and usefulness of the latter for the estimation of the state of glomerular filtration.
Optimum multimodality examination of the pancreas includes sonographic, radioimmunological, scintigraphic and angiographic studies. Sonography is a method of choice to study anatomotopographic features of the pancreas. The radioimmunoassay is intended both for the mass screening of patients with hepatogastro-duodenal diseases and for the differential diagnosis of chronic pancreatitis by the nature and type of disease. The use of pancreatoscintigraphy should be restricted in view of considerable exposure of patients. Angiography and angioscanning should be performed strictly according to indications with suspicion for a pancreatic tumor.
The authors present a simplified technique for the processing of the results of a study performed in a department that is not fitted out with a computer. Primary data are collected using a gamma-chamber with an analyzer or a radiocirculograph. Three examples of the graphic approximation of primary dynamic curves are given.
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The serial scintiphotography following intravenous injection of Tc99m-ertechnetate was used for examination of 50 children aged from 11 months to 14 years. The method is founded on the Tc99m-pertechnetate property of selective accumulation in the gastric mucous membrane and in Meckel's diverticulum when the latter contains the ectopic gastric mucous membrane. The inflamed diverticulum can accumulate the radionuclide, as well. Meckel's diverticulum was suspected in 7 children during examination; in 6 of them Meckel's diverticulum was found peroperatively, and in one case there was enterocyst of the ileum.
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