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Biomedical subjects

T V Ovsiannikova

Publications and source records attributed to T V Ovsiannikova.

17 recordsLinked to original sources

[Diagnosis and treatment in infertile marriage].

The paper gives data on the frequency and pattern of infertile marriage by referrals to the clinic of infertility, Center of Obstetrics, Gynecology, and Perinatology, Russian Academy of Medical Sciences. Tubuloperitoneal disorders are the leading and challenging abnormality in aphoria. Endometriosis and endocrine types of infertility occupy the second place in their incidence. Emphasis is laid on the role of laparoscopy in the complex examination of infertile females. Analysis of the causes of male infertility suggests that abnormalities resultant from sexually transmitted diseases are prevalent. The diagnosis and treatment of marriage infertility caused by immunological and psychogenic factors call for further development.

Adult↗

[Use of metergoline in the treatment of infertility associated with hyperprolactinemia].

The usage of metergoline in patients with infertility and different forms (hinds) of hyperprolactinaemia was studied for 90 days at a dose of 12 mg. It gives a possibility to stimulate ovulation in 64% of patients and gain pregnancy in 8% of patients. In order to exceed the percentage of inpregnantion the course of medicine can be enlarged up to 6 months.

Female↗

[Disorders of the hypothalamo-hypophyseal system as a cause of infertility in hyperprolactinemia].

The purpose of the study was to describe hypothalamopituitary functional status of females with infertility in combination with hyperprolactinemia. To this end, changes in prolactin, LH, FSH and TSH in response to the administration of releasing hormones (Gn--RH and TRH) and the dopamine antagonist metoclopramide were assessed in 28 patients with hyperprolactinemic amenorrhea and 5 normal cycling women. Lactotrophs were found to be resistant to functional tests, the resistance increasing as the prolactin level went up. Gonadotrophic and thyrotrophic response to functional tests, on the contrary, increased with the progress of hyperprolactinemia. A conclusion is drawn that stable hyperprolactinemia is a result of disturbance in lactotrophic receptor apparatus, for which reason lactotrophs are no longer sensitive to dophamine inhibiting effect on prolactin secretion.

Adult↗

[The causes of infertility in hyperprolactinemia].

A study was made of function of the hypothalamohypophyseal system in women with infertility combined with hyperprolactinemia. Changes in the levels of prolactin, LH, FSH and TSH in response to the administration of releasing hormones (gonado- and thyroliberin) and metoclopramide (dopamine antagonist) were determined in 28 women with hyperprolactinemic amenorrhea and in 5 women with a normal menstrual cycle. Resistance of lactotrophs to functional tests was revealed. It grew with an increase in a prolactin level. On the contrary, a response of gonado- and thyrotrophs to functional tests grew with an increase in a degree of hyperprolactinemia. The authors arrived at a conclusion that stable hyperprolactinemia resulted from disorder of the receptor apparatus of lactotrophs with the resultant nonsusceptibility of the latter to an inhibitory effect of dopamine to prolactin secretion. Proceeding from their own and literature data, the authors propose for discussion a scheme of fertility disturbance in stable hyperprolactinemia.

Adult↗

[The clinical use of andriol in the hormonal therapy of male sterility].

The paper presents the experience in administration of testosterone andekanoate (andriol) in males suffering from infertility due to idiopathic oligozoospermia. Andriol produced a positive effect on ejaculate. As a result, 25% of the wives got pregnant. The response to andriol arises from posttesticular effects on maturation of spermatozoa and stimulation of the accessory sexual glands.

Adult↗