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Biomedical subjects

T V Zakharzhevskaia

Publications and source records attributed to T V Zakharzhevskaia.

5 recordsLinked to original sources
PubMed1990

[Bronchoconstrictive and bronchodilating effects of acetylsalicylic acid in patients with bronchial asthma].

An aspirin test has been performed in 100 asthma patients. The response of the bronchi appeared contradictory: aspirin asthma on the one hand, and bronchodilatation on the other occurred in 31 and 28 patients, respectively; 41 patients appeared nonresponders. Maximum effect of the drug was noted in the small bronchi. Desensitization to aspirin and hemosorption reduced asthma patients sensitivity to nonsteroid antiinflammatory drugs.

Adolescent↗
PubMed1989

[Hemosorption in the treatment of aspirin-induced bronchial asthma].

Oral aspirin test was performed in 50 asthma patients. Of them 18 patients exhibited idiosyncrasy to the drug. All the patients were subjected to hemosorption. Subsequently, 16 patients achieved remission. The hemosorption resulted in reduction of tracheobronchial hypersensitivity, especially to PGE2 alpha. Phagocytosis and T-cell immunity returned to normal. Sixteen patients underwent aspirin desensitization which had a more potent action on the function of beta-adrenergic receptors of the smooth muscles of the bronchi. Complete desensitization in 3 patients was recorded only after 1-3 hemosorption sessions.

Adult↗