Biomedical subjects

T Valentino

Publications and source records attributed to T Valentino.

4 recordsLinked to original sources

PubMed1999

Primary non Hodgkin's lymphoma of the vagina.

The genital tract as a primary site of malignant lymphoma in women is extremely rare. This report concerns a 64 year old patient with a primary vaginal non-Hodgkin lymphoma (large cell B lineage according to the REAL classification--centroblastic type according to the Kiel classification--"G" according Working Formulation) with an unusual clinical presentation--pelvic discomfort accompanied by frequent ureteral-like colic. Due to gynecological onset symptoms and the rarity of this extranodal primary site misinterpretation of a primary vaginal lymphoma as a benign inflammatory disease or endometriosis may occur. We emphasize the importance of their recognition and also the differential diagnosis of cervical lymphoma from other neoplastic and non-neoplastic lesions.

Abdominal Pain↗

PubMed1995

Length/serum creatinine ratio does not predict measured creatinine clearance in critically ill children.

OBJECTIVE: Information regarding renal function is important in critically ill children to adjust the dosage of drugs that are eliminated by the kidneys. Methods for estimating glomerular filtration rate (GFR) based on age and serum creatinine level have shown good agreement with measured creatinine clearance (CLCR) in children without critical illness but have not been examined in critically ill children. METHODS: CLCR (24 hours) was measured (CLCR-measured) in 100 individuals (aged 5.6 years [range, 0.1 to 20.8 years]) admitted to a pediatric intensive care unit. Urine was collected by indwelling bladder catheters. Serum levels were determined. CLCR was calculated (CLCR-measured) according to the standard formula. GFR was estimated (CL-estimated) according to a published method, in which GFR is based on serum creatinine levels, patient length, and a constant that varies with the age and sex of the child. For each patient, the percentage difference between methods was calculated as the difference between the methods divided by the average obtained by the two methods and expressed as a percentage. Bias was calculated as the absolute value of the percentage difference. RESULTS: CLCR-measured and CL-estimated were significantly correlated (CLCR-measured = 0.57 CL-estimated + 16.8; r = 0.68; p < 0.001). However, CL-estimated was greater than CLCR-measured in 84 patients. The difference ranged from -230 to +123 ml/min/1.73 m2 (mean -25.9 ml/min/1.73 m2 [95% confidence interval, -18.1 to 33.7 ml/min/1.73 m2]). The mean percentage difference between the methods was also large (-38.1% [95% confidence interval, -47.1% to 29.2%]) and ranged from -153.2% to 102.1%. The mean bias was 45.2% (95% confidence interval, 37.7% to 52.8%). In 36 of 100 patients the discrepancy between the two methods was greater than 50%. Adjusting for weight percentile, as a proxy for abnormal muscle mass, did not improve the model. CONCLUSION: A method to estimate GFR in children that is based on age and sex, but not critical illness, does not correspond with measured 24-hour CLCR. Use of this method to adjust dosage of drugs eliminated by the kidney might result in significant overdosage in most critically ill children.

Adolescent↗

PubMedDate not supplied

Correlation between interdental occlusal plane and plantar arches. An EMG study.

The Authors carried out an experimental study on a homogeneous group of young people to provide evidence of functional correlation among masticatory muscles and, indirectly, between changes to the interdental occlusal plane and modifications of the plantar arches due to talipes valgus and flat foot. In the two analysed conditions, the masticatory muscles undergo different functional alterations. This is due to the fact that the mechanoreceptors in the tendons of the muscles governing the plantar arch configuration are stimulated in different ways during the activation of long osteoarthromuscular chains. Dental specialists will have to take these correlation into account when diagnosing TMJ disorders.

Adult↗

PubMedDate not supplied

An EMG study on TMJ disorders.

The Authors have described a clinical case involving a patient with a classical TMJ syndrome and a full range of typical symptoms, both dental and non-dental. The patient underwent a set of EMG tests before his occlusal plane was restored using a special material, immediately following reconstruction and, lastly, three months following the application of a prosthesis. The findings of these EMG tests have shown that the complex symptoms reported by the patient could be traced back to his occlusal plane. Once it was reconstructed, all the typical dental and non-dental symptoms of TMJ disorders subsided.

Dental Occlusion, Traumatic↗