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T Videman

Publications and source records attributed to T Videman.

106 records · Page 6Linked to original sources
PubMed1978

An experimental model of osteogenesis: a closed in vivo culture system using diffusion chambers.

Part of young mouse radii were isolated and transplanted into an intraperitoneal Millipore diffusion chamber. The survival of the implants was followed for 22 days, using morphological criteria, and by autoradiography with tritiated thymidine. Periosteal cells and epiphyseal plate chondrocytes survived well for one to two weeks. DNA synthesis was noted up to the twenty-second day of culture. Osteogenetic cells proliferated well in transplants of shorter duration, but in the third week there was overgrowth by fibroblasts. The method seems well suited for the culture of osteogenetic cells as whole-bone pieces for at least one to two weeks.

Animals↗
PubMed1977

Changes in bone formation during immobilization and development of experimental osteoarthritis.

The effect of immobilization on bone formation in the knee and hip was studied by means of oxytetracycline. One leg of 11 growing and 13 adult rabbits was immobilized so that the knee was held in extension but the hip was free. In the knee, degenerative changes developed consistently with a severity proportional to the length of the immobilization time. In most of the rabbits given oxytetracycline 1-13 days before they were killed considerably more oxytetracycline was incorporated in the bone in the immobilized knee region and slightly more in the hip region of the same leg than in the corresponding areas of the other leg. This indicates an increased turnover of bone tissue in the immobilized leg compared with the non-immobilized leg.

Animals↗
PubMed1976

Changes in 35S-sulphate uptake in different tissues in the knee and hip regions of rabbits during immobilization, remobilization the development of osteoarthritis.

In order to observe phenomena accompanying the development of osteoarthritis of the rabbit knee, consistently appearing within 4-6 weeks as a consequence ofimmobilization of this joint, studies on 35S-sulphate (Na2 35SO4) uptake were carried out. The investigation suggests that immobilization of the knee leads within 2-4 weeks to increased sulphate uptake in bone, cartilage and ligaments in the knee region and in the hip (not immobilized) of the same leg. The first marked changes in 35S-sulphate uptake were found in the ligaments and the articular cartilage as early as after 4 days of immobilization.

Animals↗
PubMedDate not supplied

Low-back pain in nurses and some loading factors of work.

Questionnaires were sent to qualified nurses (QNs) and nursing aides (NAs) to study the prevalence of low-back pain (LBP) and sciatica in relation to age, work-load, free time activities, menstruation, pregnancies and number of children. LBP and sciatica severe enough to make them unfit for daily tasks were significantly more common in NAs. Back injury and disability pension due to sciatic symptoms were also more common in NAs. Occupationally, NAs had twice the amount of lifting, bending, and rotation, while QNs reported more sitting and standing at work. Under the age of 30, the heaviness of the work was related to LBP in both NAs and QNs. It was concluded that prevention should be directed to improvements in the occupational work load, particularly for younger nurses.

Adult↗
PubMedDate not supplied

Radiographic vs. direct measurements of the spinal canal of the thoracolumbar junctional region (T10-L1) of the spine.

Midsagittal diameter (MSD) and interpedicular distance (IPD) in the thoracolumbar junctional region (T10-L1) of 24 male cadaveric spines were measured both from radiographs and directly from bones after removal of the soft tissues in order to assess the accuracy of plain radiographs. In addition surface areas of the vertebral canals were measured also from bone samples. It was found that the mean difference between bone and radiographic measurements in the IPD on different vertebral levels was 1.0 mm (r = 0.98). The MSD was a more difficult measurement, but the correlation coefficient was still 0.70, the mean difference being 0.7 mm or less. The sum of the MSD and IPD showed good relationship with the cross sectional area of the spinal canal, and the correlation coefficient was 0.77 (P less than 0.001).

Adult↗
PubMedDate not supplied

Radiographic versus direct measurements of the spinal canal at lumbar vertebrae L3-L5 and their relations to age and body stature.

The role of the narrow lumbar spinal canal in back and sciatic pain is well established. The accuracy of measurements obtained from lumbar radiographs was therefore analyzed in lumbar spine specimens taken from 132 male cadavers. After removal of soft tissues, the same distances were measured on the bones of 80 specimens. Comparisons were made after correction for magnification, the radiographic measurements of interpedicular distances being, on average, 2 mm greater at L3 than the osteologic ones and 4 mm greater at L5. Interarticular distances, midsagittal diameters, and pedicular lengths were, on average, 1 mm greater and foraminal anteroposterior measurements 1 mm less than the osteologic ones. Body stature correlated with interpedicular and interarticular distances, pedicular length, and foraminal anteroposterior measurements. In older age groups, the midsagittal diameter tended to be reduced. A number of correlations were found between the five measurements, e.g. between the anteroposterior diameter of the intervertebral foramen and the pedicular length. Measurements in the transverse plane were independent of those in the anteroposterior plane. These results confirm and amplify preliminary observations and indicate the potential value of simple measurements on lumbar spine films as an alternative to more sophisticated and expensive radiologic investigations.

Adult↗
PubMedDate not supplied

Plasma glycosaminoglycans in experimental osteoarthritis caused by immobilization.

The right knees of adult rabbits were immobilized under conditions known to produce either "developing" osteoarthritic lesions or advanced, "chronic" lesions typical of osteoarthritis. The concentration of plasma glycosaminoglycans was assayed and found to be unchanged in "developing" osteoarthritis but significantly increased in animals with "chronic" lesions of the immobilized knee. Assays of plasma glycosaminoglycans may be useful in the assessment of osteoarthritis.

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