PubMed Health⌕ Search

Biomedical subjects

T W Briggs

Publications and source records attributed to T W Briggs.

At least 19 recordsLinked to original sources

Primary atypical sacral meningioma--not always benign.

We present a case of an atypical recurrent meningioma of the sacrum with pulmonary metastasis in a 31-year-old man. He presented with deep-seated buttock pain and urinary hesitancy for 3 months. MRI revealed a lesion occupying the central and left side of the sacral canal at the S1-S2 level. Surgical excision of the lesion via a posterior approach was undertaken, and the patient became symptom-free post-operatively. Histology confirmed atypical meningioma. Eight months later he re-presented with similar symptoms, and MRI confirmed local recurrence. The patient underwent left hemisacrectomy. Six months later he again presented with low back pain and MRI confirmed a second local recurrence. A CT scan of the chest showed multiple lung metastases. The patient died of a severe chest infection 18 months later.

Adult↗

Autotransfusion drains in total knee replacement. Are they alternatives to homologous transfusion?

We prospectively randomised 104 consecutive patients undergoing primary cemented total knee arthroplasty into two groups of 52 patients each, with one group to receive a standard suction drain (Redivac) and the other, an autologous transfusion drain (Bellovac). Randomisation was achieved using the software programme MINIM: , which was set to randomly allocate patients to either of the two groups based on their age, sex and body mass index (BMI). All procedures were performed under pneumatic tourniquet. Drains were released in the recovery room 20 min after surgery and removed 24 h following surgery. Blood collected in the standard suction drain (control group) was discarded, while blood collected in the autologous transfusion drains (study group) was transfused unwashed back to the patient within 6 h of collection. Thirteen patients (25%) in the study group had two or more units of homologous blood transfused in addition to the blood collected postoperatively and re-transfused (average: 438 ml). Twelve patients (23%) in the control group had two or more units of homologous blood transfused. No sepsis, transfusion reactions or coagulopathies were associated with the autologous blood transfused in the study group. The use of the autologous transfusion system (Bellovac) proved to be safe but failed to reduce the need for postoperative homologous blood transfusion following uncomplicated total knee arthroplasty.

Aged↗

The Kinemax total knee arthroplasty. Nine years' experience.

We reviewed the outcome of 422 primary cemented Kinemax total knee arthroplasties implanted into 369 patients over a period of five years, from January 1989. The operations were carried out at two NHS district general hospitals and one teaching hospital by 31 surgeons. During the period of review, 49 patients died and ten knees were lost to follow-up (68 knees). The mean Knee Society score improved from 28 before to 89 after surgery, and the mean function score increased from 23 to 79. The range of flexion improved from 92 degrees to 105 degrees. These improvements were maintained throughout the period of study. At the latest review radiolucent lines of 1 mm were seen around 15% of tibial components, 1.4% of patellar components and 9.5% of femoral components. In no case were these changes progressive. Using revision as the endpoint, cumulative survival was 99% after five years and 96.95% after nine years. All revisions were undertaken for deep infection or secondary trauma. Our study has shown that the Kinemax total knee replacement, when carried out with retention of the posterior cruciate ligament by surgeons of varying experience, produces very satisfactory results in the medium term.

Aged↗

Osteofibrous dysplasia of the ulna.

Osteofibrous dysplasia is a rare condition usually ffecting the tibiae and fibulae of males in the first two decades of life. Involvement at the ulna has also been reported in some cases. We describe an extensive, rapidly progressive lesion of the ulna in a three-year-old girl. The progression of the disease accelerated after a local marginal removal, and required extensive resection of the ulna with reconstruction using a fibular autograft. The particular features of this case are the change in the aggressive nature of the condition, which has not been previously reported. We believe that this is only the second recorded case of histologically proven involvement of the ulna.

Bone Transplantation↗

A functional analysis of massive knee replacement after extra-articular resections of primary bone tumors.

We performed a functional analysis of massive knee replacements after extra-articular resection of primary bone tumors. Patients did not score as highly on the Musculoskeletal Tumour Society Score and Knee Society Score (P < or = .01) as patients who had undergone intra-articular resection. Lower scores were achieved for emotional acceptance (P < or = .01), functional restriction (P < or = .05), walking distance (P < or = .05), and managing stairs (P < or = .05). These patients had a significantly greater extension lag (P < or = .01) and greater fixed flexion (P < or = .05). This functional deficit is primarily due to a compromised extensor mechanism inherent in the type of surgical resection necessary to achieve adequate removal of the tumor.

Adolescent↗

Cementless fixation for primary segmental bone tumor endoprostheses.

To combat the high incidence of aseptic loosening for young patients and for patients with failed implants after resection for bone tumors, intramedullary cementless fixation of massive tumor implants was investigated. These implants consist of a hydroxyapatite coated titanium stem. To date, 47 of these prostheses have been inserted for the treatment of primary bone tumors. Radiographs indicate that the stems are osseointegrated. Radiolucent lines have not been seen between the implant and the bone. Bone remodeling changes have been observed. In several cases in which the implant was not seated properly on the transaction site, bone grew to the shoulder of the implant. Bone remodeling was particularly evident in stems that were coated over their entire surface. In these cases, the implant induced local bone resorption so that the bone around the midstream region became thinner, with resorption of cortical bone on the periosteal surface and maintenance of bone on the endosteal surface adjacent to the stem. This effect was attributed to stress shielding, and a three-dimensional finite element model using loading data obtained from a telemetry study indicated that, where the stem was bonded to the bone over the entire surface, stresses in the outer cortex became reduced. In the finite element model, reducing the region of hydroxyapatite coating to approximately 1/3 of the stem length reduced the extent of the low-stress area in the outer cortex. Subsequently, prostheses have been coated with hydroxyapatite over only approximately 1/3 of their stem. This method of fixing the massive endoprosthesis to the bone is thought to be successful in the short-term and offers an alternative to cemented fixation.

Bone Neoplasms↗

Use of extendable total femoral replacements in children with malignant bone tumors.

Although rarely required, extendable reconstruction devices for replacing the entire femur offer children with malignant bone tumors the opportunity of a nearly normal development by overcoming an expected leg length discrepancy. Femoral integrity can be restored, allowing most patients to walk without the use of aids. There are no data available to provide evidence regarding long term results and morbidity in such patients. Six patients (range 2-12 years of age), three with osteogenic osteosarcoma and three with Ewing's sarcoma, were treated between 1988 and 1996 with custom made Stanmore extendable prosthetic total femoral replacements. One patient died 12 months after surgery because of complications relating to pulmonary metastasis. The remaining five patients were observed between 2.7 and 8.9 years (average, 5 years). No tumor recurrence has been recorded and no amputation has been performed. All surviving patients underwent an average of 9.4 operative procedures (range, 4-16 procedures) including 6.4 extension procedures (range, 3-10 procedures), and one prosthetic revision (range, 0-3 procedures). Five revisions in two patients were necessary because of infection, loosening of the prosthesis, mismatch between femoral head and acetabulum, or full extension of the extending mechanism. The functional results were measured in accordance with the Musculoskeletal Tumor Society rating score, with an average result of 77.3%. Total femoral replacement in a growing individual achieves good functional results yet has various risks for an uncertain outcome. Careful selection of the patient and realistic appraisal of the long term prospects are essential for successful treatment.

Bone Neoplasms↗

Bilateral demyelinating neuropathy in a solitary lytic and sclerotic myeloma of the proximal humerus: a case report.

Mixed lytic and sclerotic myeloma are uncommon and occur at an earlier age than multiple myeloma in areas of persistent haemopoiesis. Their characteristic symptoms are pain, swelling and pathological fractures and they are usually detected at an early stage. We report a case of a mixed sclerotic/lytic myeloma of the humerus presenting at an unusually advanced stage and associated with a bilateral progressive demyelinating peripheral sensory and motor polyneuropathy resembling polyradiculitis. The neurological changes partly disappeared after the tumour had been resected which suggests that nerve reconstitution may occur due to reversal of the demyelination.

Bone Neoplasms↗

Stanmore custom-made extendible distal femoral replacements. Clinical experience in children with primary malignant bone tumours.

The use of extendible distal femoral replacements is a relatively new treatment alternative for malignant bone tumours in growing individuals. Although their appearance was widely appreciated, questions about functional practicality and longevity remain unclear. With longer follow-up, advantages of immediate functional restoration and beneficial psychological aspects seem to be overshadowed by an increase in complications such as aseptic loosening, infection or prosthetic failure. We have reviewed 18 children with such tumours who were treated between 1983 and 1990 by custom-made Stanmore extendible distal femoral replacements. Four died from metastatic disease within 2.5 years of operation and two required amputation for local recurrence or chronic infection. The remaining 12 patients were followed for a mean of 8.7 years (6 to 13.2). A mean total lengthening of 5.2 cm was achieved, requiring, on average, 4.3 operations. Using the Musculoskeletal Tumor Society rating score the functional result at review was, on average, 77% of the expected normal function, with seven patients achieving > or = 80%. Revision of the prosthesis was required in ten patients, in six for aseptic loosening, at a mean of 6.2 years after the initial procedure.

Adolescent↗

Ionising radiation: are orthopaedic surgeons' offspring at risk?

The hazards of exposure to ionising radiation are well documented. Fears have been raised that occupational exposure to ionising radiation by orthopaedic surgeons may have detrimental effects on the future health of their unborn offspring. The current members of the British Orthopaedic Trainees' Association and orthopaedic consultants appointed during the last 5 years in the United Kingdom were contacted using a postal questionnaire. Obstetricians and gynaecologists of a similar age group were also contacted to act as the control group. The collected data were compared with the latest national data as published by the Office of Population Censuses and Surveys for England and Wales (OPCS, 1991). In all, 504 questionnaires were posted to orthopaedic surgeons and 1597 to obstetricians and gynaecologists. Reply rates were 334 (66%) and 986 (62%), respectively. Our data reveal a higher rate of congenital abnormalities as compared with the normal population in both groups (P < 0.001). However, there were no statistically significant differences in the rate of congenital abnormalities between the offspring of orthopaedic surgeons and obstetricians and gynaecologists (P = 0.78). These findings suggest that the increased rate of congenital abnormalities observed in both groups is more likely to be associated with factors other than exposure to X-rays. In this study, male surgeons had a higher incidence of female children compared with the normal population (P = 0.01). The incidence of childhood malignancies does not appear to be raised in either group. These findings suggest that the current levels of occupational exposure to X-rays by orthopaedic surgeons is unlikely to be associated with an increased risk of congenital abnormalities or childhood malignancies in their children.

Adult↗

Radiation exposure of orthopaedic trainees: quantifying the risk.

Interest in radiation protection issues has recently grown within the medical profession. Several investigators have examined the radiation exposure of orthopaedic surgeons using X-rays during trauma surgery, and found that doses received are within acceptable limits. These studies however, have been performed over short time-periods or have been confined to single procedures only. In this paper, we report the results of monitoring of the total exposure across all procedures of a group of orthopaedic surgeons over a 4-month period. Doses received were all below the International Commission on Radiological Protection (ICRP) recommended limits. While these results are reassuring, they do not represent grounds for complacency. Continued vigilance will be essential as work practices continue to change. In orthopaedics, in contrast with other specialties, the limiting dose is that to the hands. In view of this finding, extremity dosimetry for surgeons regularly using X-rays in theatre should be considered.

Gloves, Protective↗

Pin placement in pelvic external fixation.

Early external fixation of major pelvic fractures reduces haemorrhage and mortality. The best site and method for pin placement remains unresolved. The superior iliac crest is biomechanically disadvantageous and hinders access to the abdomen. Low pin placement between the anterior iliac spines has been proposed as a better solution. A case-controlled study was performed on cadavers using a jig designed to place external fixator pins accurately in the pelvis; the study tested the safety of pin placement and the mechanical strength of the two placement sites. The results showed that pins could be placed safely using this method and that low placement in cadaveric bone is as strong as that of the conventional placement.

Biomechanical Phenomena↗

Unrecognised joint penetration in treatment of femoral neck fractures.

Screw devices used to treat fractures of the femoral neck are usually positioned under image-intensifier control, using anteroposterior and lateral views. The volume projected by these views is over 27% larger than the femoral head; the tips of screws so placed may be outside the femoral head. This can be avoided by placement within the central two-thirds of the head: we have designed a template which can confirm safe placement.

Anthropometry↗

Isolated tibial fractures in children.

In a review of 65 tibial fractures in children of which 25 were isolated and not associated with a fracture of the fibula, we found that isolated tibial fractures were not uncommon, and accounted for one-third of all tibial fractures in children under 11 years of age. They occur after two types of force, the most common being indirect violence involving a torsional injury. Isolated fractures unite easily without delayed union. Isolated transverse fractures never displace, and consequently do not require further radiographs following the initial check radiograph after the application of the plaster cast. In seven of the 25, the fracture was spiral or oblique and displacement into varus occurred for up to 2 weeks after the initial injury. These need careful follow-up, with weekly radiographs for the first 2 weeks. If the varus displacement is greater than 5 degrees we recommend manipulation in that period. After this time the fracture site is sticky, and manipulation will fail. Non-operative treatment is recommended for this fracture.

Casts, Surgical↗

Mitchell's osteotomy using internal fixation and early mobilisation.

We present the results of a prospective trial of osteotomy of the metatarsal neck for hallux valgus in 31 feet of 23 women, using a new stapling device with no plaster splintage and early weight-bearing. Surgery was performed for pain (29 feet) and difficulty with footwear (nine feet). The average time for return to light work was 3.3 weeks, and to full work 8.3 weeks after operation. Seventeen patients had full recovery within three months and 21 of the 23 patients had complete relief of pain. Shoes were more comfortable in 17 feet and 9 patients could wear narrower shoes. Only two patients were unsatisfied with the appearance of the foot. All the osteotomies united, and the average hallux valgus angle was improved on radiographs from 35 degrees to 23 degrees. The mean first metatarsal angle was reduced from 16 degrees to 11 degrees. The new technique allows more accurate surgery and easier postoperative management.

Adolescent↗