A new screening method for investigating microbial interactions.
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Biomedical subjects
Publications and source records attributed to T W MacFarlane.
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Short-chain carboxylic acids produced by Candida albicans in glucose supplemented batch cultures and in human denture plaque has been qualitatively and quantitatively analysed using isotachophoresis. This rapid, simple and relatively new technique which has advantages over other conventional methods, such as gas liquid chromatography, could be a valuable tool in the analysis of carboxylic acids produced by other yeasts of clinical and industrial importance.
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A retrospective study was carried out in thirty-seven patients who had recurrent chronic atrophic candidosis (CAC). The factors commonly believed to predispose to CAC were investigated, including corrected whole blood folate, iron saturation, and vitamin B12. The incidence of CAC based on clinical and microbiologic criteria was assessed before and after antifungal therapy and correction of predisposing factors. No significant difference was found. Hence, the role of additional, less well-known predisposing factors in the etiopathology of CAC should be considered when one is treating patients with recurrent, chronic Candida infections.
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Thirteen cases of staphylococcal sub-mandibular lymphadenitis in children are presented and the diagnosis and treatment are discussed. All but one of the strains of Staphylococcus aureus isolated were resistant to penicillin, while the converse was true for erythromycin. Epidemic strains of Staphylococcus aureus were not found when bacteriophage typing was carried out on isolates from seven of the 13 patients.
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Actinomycosis is often considered to be a rare disease in the oral region. A retrospective study of the Routine Diagnostic Services in Glasgow Dental Hospital revealed 39 cases in which actinomyces were detected, indicating that this organism is not infrequent in oral infections and may be seen in a variety of lesions.
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