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Biomedical subjects

T W Nichols

Publications and source records attributed to T W Nichols.

10 recordsLinked to original sources

Drug utilization.

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Arteriosclerosis↗

Pseudomembranous colitis. A complication of sulfasalazine therapy in a patient with Crohn's colitis.

Pseudomembranous colitis is a potentially life-threatening acute medical problem usually associated with a history of previous antibiotic exposure. Presented here is a case of sulfasalazine associated pseudomembranous colitis in a patient with known Crohn's colitis. The diagnosis was confirmed by identifying Clostridium difficile toxin in the stool. This a newly reported complication of sulfasalazine therapy.

Adult↗

Spontaneous rupture of the spleen. An unusual complication of Crohn's disease.

Crohn's disease is associated with many local complications. Spontaneous rupture of the spleen secondary to Crohn's colitis with a fistulous tract into the adjacent fixed spleen has never been reported in the literature. A case report and a brief review of spontaneous splenic rupture and colonic perforation in Crohn's disease is presented.

Colonic Diseases↗