The Delaney debate is losing focus.
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Animals↗
Biomedical subjects
T W Orme
Publications and source records attributed to T W Orme.
Central role of toxicity tests in the prevention of cancer.
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Animals↗
Transformation of mouse cells after infection with ultraviolet irradiation-inactivated herpes simplex virus type 2.
A transformed mouse cell line (H238) was obtained following the infection of 238 mouse cells with ultraviolet (UV) irradiation-inactivated herpes simplex virus type 2 (HSV-2). The transformed cells produced tumors with a 100% incidence within 8 weeks in 6-week-old syngeneic BALB/c mice at an inoculum of 1 times 10(6). Indirect immunofluorescence (IF) tests revealed the presence of HSV antigens in the transformed cells. Antibodies to HSV-2 were found in the sera of tumor-bearing animals by neutralization and IF techniques. Neither HSV-2 infectious virus nor viral antigens could be detected by the transfer of transformed-cell DNA into permissive cells.
Animals↗
The analysis of 2-acetamido-2-deoxyaldose derivatives by gas-liquid chromatography and mass spectrometry.
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Acetamides↗
A unique serum protein in mice with various tumors.
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Adenocarcinoma↗
Preparation of membrane fractions with enhanced tumor-transplantation-antigen activity from tumor cells infected with influenza virus.
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Animals↗
Fatty-acid elongation in a mutant of Saccharomyces cerevisiae deficient in fatty-acid synthetase.
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Acetates↗
Phosphorylation linked to ascorbate oxidation in Mycobacterium phlei.
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Aniline Compounds↗