Biomedical subjects
Publications and source records attributed to T W Wood.
Over the past eleven years we have repaired seven rectourinary fistulas using a modified York-Mason transrectal transsphincteric approach. The simplicity of this one-stage procedure has demonstrated its cost effectiveness compared with the standard three-stage procedure (colostomy and cystotomy, fistula repair, and colostomy takedown).
1. Drug administration studies using diisopropylamine dichloroacetate (DADA) and diisopropylamine (DIPA) were conducted in Thoroughbred and Standardbred horses to assess physiological effects and develop detection methods. 2. Four horses received 0.08 mg DADA/kg body wt and showed no changes in heart and respiratory rates or body temperature as measured over a 1-hr period after administration. A transient diuretic effect was found to occur in 2 mares dosed with 0.80 mg DADA/kg body wt. 3. A qualitative detection method using thin-layer chromatography was developed to detect DIPA, the major metabolite of DADA in equine urine. A quantitative detection method (lower limit of detection 0.5 micrograms/ml urine) for this metabolite was also developed using gas chromatography. 4. Neither DADA or the free base, DIPA, were detectable in equine blood samples using the above-mentioned methodologies.
Sapphire tips for Nd:YAG lasers fibers have been introduced recently. The increased energy density improves the cutting effect while, reportedly, preserving the hemostatic properties of Nd:YAG laser energy. The capacity of sapphire tip laser fibers to facilitate partial nephrectomy was tested in mongrel dogs. No advantage for this technique was demonstrated compared to standard methods of partial nephrectomy.
We report a case of an asymptomatic pelvic mass that was found during examination for a left ureteral stone. After stone management preoperative computerized tomography demonstrated a 6 by 6 cm. midline pelvic mass posterior to the bladder. Lumbar angiography was normal. A liver/spleen scan and splenic angiography were not performed. At exploration the mass was found to be an accessory pelvic spleen. The embryology, presentation, diagnosis and treatment are discussed.
A technique for partial nephrectomy using a combination of an Ultrasonic Surgical Aspirator and a neodymium:YAG laser provided better hemostasis and decreased total operative time compared to standard methods. Delayed hemorrhage was not seen, and thermal damage to the remaining renal parenchyma was minimal.
A Cavitron Ultrasonic Surgical Aspirator (CUSA) was used to isolate and skeletonize parenchymal renal vessels during 20 partial nephrectomies performed on 10 dogs. After isolation of the renal vessels, hemostasis was obtained by direct application of neodymium:YAG laser energy. Blood loss and total operative time were reduced compared to a control series of partial nephrectomies performed with a scalpel. The combination of Cavitron Ultrasonic Surgical Aspirator plus a Nd:YAG laser appears to offer advantages compared to either modality used alone or to standard techniques for partial nephrectomy.
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