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T Walde

Publications and source records attributed to T Walde.

10 recordsLinked to original sources
PubMed2005

The Nottingham health profile-experiences after hip revision arthroplasty.

INTRODUCTION: Considering patients after hip revision arthroplasty postoperative quality controls allows an evaluation of the individual implant situation as well as the achieved postoperative quality of life. With regard to a possible loss of data reliable statements about the used implant system with special consideration to the implant survival rate could not be received. In this connection standardized self-assessment questionnaires like the Nottingham Health Profile (NHP) are in the centre of interest. The main focus of this study was to demonstrate a correlation between the Nottingham Health Profile and the Merle d'Aubigne (MDA) Score. PATIENTS AND METHODS: Fifty-one patients after femoral stem revision were re-examined. All patients received a written appointment for an ambulatory re-examination together with the NHP 4 weeks before. The clinical evaluation was carried out by using the MDA Score. Correlations between the NHP and the MDA were calculated. RESULTS: Overall the data of 39 patients could be evaluated completely. Three patients (5.9%) did not appear to the ambulatory re-examination, four patients (7.8%) deceased in the meantime. With further five patients (9.8%) the NHP questionnaire could not be rated due to an incorrect treatment. The mean follow-up after revision was 5.8 years. Correlations between the category 'Pain' NHP/MDA as well as to the combination of the NHP-categories 'Pain' + 'Physical Mobility' and the total MDA-Score could be demonstrated. CONCLUSION: Out of our personal experiences the use of the NHP makes an individual follow-up evaluation after revision hip arthroplasty possible. Patient-referred changes can lead to direct re-examinations. Correlation coherences between the NHP and the MDA could be demonstrated equivalent to already published results. In what way a survival rate analysis of an implant by using the NHP is possible could not be answered clearly. It has to be included that wrong answered questionnaires lead to an additional drop-out rate beneath the lost to follow-up rate.

Activities of Daily Living↗
PubMed2004

[Evaluation of regional wall motion abnormalities of the heart--comparison with doppler tissue echocardiography, MR-tagging and levocardiography].

PURPOSE: To compare the visual analysis of magnetic resonance imaging (MRI) with the tagging technique and Doppler tissue echocardiography with invasive ventriculography in detecting and quantifying regional left ventricular wall motion abnormalities. MATERIALS AND METHODS: Sixteen patients with coronary artery disease and a history of prior myocardial infarction underwent invasive ventriculography, Doppler tissue echocardiography and MR-tagging within one week. Regional wall motion abnormalities (WMA) were detected in all patients. WMA were graded as normal = 1; hypokinetic = 2; akinetic = 3; or dyskinetic = 4. For agreement between MRI, echocardiography, and ventriculography the kappa coefficient (kappa) according to Cohen was calculated. RESULTS: The kappa coefficient (kappa) was 0.962 for agreement between MRI and echocardiography and 0.602 for agreement between MRI and ventriculography as well as between echocardiography and ventriculography. CONCLUSION: Reliable analysis of regional left ventricular wall motion abnormalities is feasible using visual analysis of MR-tagging. MRI and Doppler tissue echocardiography detect more WMA than invasive ventriculography and grade them as more severe.

Aged↗
PubMed1994

Acute influence of beta-adrenergic antagonists on left ventricular diastolic function: contrasting results after administration of celiprolol and metoprolol.

Various beta-adrenergic receptor antagonists have different effects on myocardial function. A clinical study was performed in 30 patients with symptomatic coronary artery disease and systemic hypertension to compare the effects of single intravenous doses of 0.15 mg/kg celiprolol (n = 16) (third generation beta-blocking agent) and metoprolol (n = 14) (second generation) on left ventricular diastolic function. Parameters derived from pressure, volume, flow, time intervals and their combination were used to characterise diastolic function. After celiprolol administration, parameters of diastolic myocardial function improve (dp/dtip-; relaxation time constant T1, peak filling rate PFR; first-third filling rate FF1/3 or diastolic wall stress-time integral Sigdiasc) or remain unchanged. In contrast, after metoprolol administration parameters of diastolic function seem to be deteriorated (dp/dtip-, T1; Sigdiasc). This indicates an improvement in myocardial relaxation and filling under the influence of celiprolol but not under metoprolol. The left shift of the pressure-volume loops after celiprolol (n = 13), in contrast to metoprolol, supports this interpretation. Celiprolol did not show any deterioration of diastolic function in patients with coronary heart disease and arterial hypertension under these acute conditions.

Adrenergic beta-Antagonists↗
PubMed1993

Diastolic heart function--pathophysiology, characterization, and therapeutic approaches.

In recent years diastolic cardiac function has attracted increasing attention since parameters of diastolic function were found to be altered earlier or more specifically than parameters of systolic function. Diastolic cardiac function is determined by both active (muscular relaxation, redistribution of calcium, synchronization, etc.) and passive (myocardial structure, fibrosis, etc.) factors. As a consequence, a comprehensive assessment of diastolic cardiac function cannot be based on one single parameter. For a complete analysis of diastolic function it is necessary to perform invasive diagnostic procedures involving the measurement of atrial and ventricular pressures, as well as the registration of volume changes with a high time resolution. In addition, it is necessary to measure wall thickness and ventricular configuration, so that apart from filling parameters the stress-strain relationship can be obtained. Noninvasive techniques (Doppler echocardiography, radionuclear ventriculography, apexcardiography) may suggest alterations in diastolic function as well. They ought to be complemented by additional diagnostic procedures (pulmonary pressure, stress testing, etc.). Therapy must consider potentially harmful effects on diastolic function parameters, particularly if changes in myocardial oxygen consumption may result (heart rate, parietal wall stress). Calcium antagonists (verapamil, diltiazem, nifedipine), phosphodiesterase inhibitors (milrinone), beta-adrenergic agonists and antagonists with vasodilating effects (e.g., celiprolol) all have beneficial effects on diastolic myocardial function. A range of diastolic function parameters is being reviewed in the following paper. Their role in the estimation of cardiac function and their responsiveness to therapy in hypertrophy, cardiomyopathy, and coronary heart disease is being discussed.

Adrenergic beta-Antagonists↗
PubMed1990

[Determination of pressure-volume relations from ventriculographs using catheter tip manometers].

The evaluation of cardiac function alone from pressure and volume data can lead to misinterpretations. By linking of pressure and volume data a variety of new parameters can be calculated. Computer techniques allow the evaluation not only of cardiac work, but also of acceleration work and the efficiency of heart power. As an example of double blind study with CHD patients the measurement of such parameters under invasive diagnostics is demonstrated, facilitating a detailed evaluation of cardiac function.

Adrenergic beta-Antagonists↗
PubMed1990

[Acute changes of coronary and global hemodynamics in patients with angina pectoris and arterial hypertension caused by celiprolol and metoprolol].

In 30 hypertensives with angina pectoris the acute action of beta-blockers Celiprolol and Metoprolol on the global and coronary haemodynamics was tested within cardiac catheter diagnostics. In accordance with no long-term effects Metoprolol acts negatively inotrope, chronotrope as well as pre- and post-load increasing. Celiprolol lowered the pre- and postload, and increased the cardiac output, but did not influence the heart rate. Both medicaments increased coronary flow and myocardiac oxygen consumption. From the mentioned effects important conclusions for therapy with both Beta-blockers can be derived.

Adrenergic beta-Antagonists↗
PubMed1989

[The effect of ionic and nonionic contrast media (amidotrizoate, iopromide) on cardiac function (contractility, relaxation, perfusion)].

In 30 patients the influence of ionic (Amidotrizoate) and non-ionic (Iopromide) contrast agents on the heart parameters contractility, relaxation, perfusion and the rate of extrasystoles was investigated. They were significantly less influenced by Iopromide than by Amidotrizoate. A negative inotropic action was detectable only for Amidotrizoate. It is concluded that non-ionic contrast media should be used especially for critical patients.

Coronary Circulation↗