PubMed Health⌕ Search

Biomedical subjects

T Wember

Publications and source records attributed to T Wember.

8 recordsLinked to original sources
PubMed1991

Circadian rhythms of urine osmolality and renal excretion rates of solutes influencing water metabolism in 21 healthy children.

Circadian rhythms of urine excretion, urine osmolality and renal excretion rates of sodium, chloride, potassium, creatinine and urea were studied for 3 days at home in 21 healthy children aged 6-11 years. Urine production as well as renal excretion rates of all solutes studied increased significantly during daytime and had minimum values at night. The peak of potassium and chloride excretion rates occurred earlier in the day than that of sodium. Considering all children together, no circadian rhythm was seen for urine osmolality. However, 9 children had evident but individually different rhythms of urine osmolality, changes which did not seem to correspond to the daily distribution of water intake. Circadian rhythmicity of urine osmolality and renal excretion rates of the main solutes should be considered in diagnostic and therapeutic procedures concerning fluid and electrolyte metabolism.

Body Water↗
PubMed1988

3-Methylhistidine/creatinine ratio in urine from low-birth-weight infants. Statistical analysis.

3-Methylhistidine and creatinine concentrations were determined in 45 24-hour urine samples collected in 380 single voidings from 23 preterm infants (gestational age: 30-36 weeks, median: 33 weeks; birth weight: 1,613 +/- 219 g; age: 9-83 days postpartum) and from 7 infants small for gestational age (birth weight: 2,061 +/- 203 g; age: 2-30 days postpartum). Statistical analysis shows that diurnal variations of the ratio 3-methylhistidine/creatinine are negligible. The variability of this ratio is chiefly caused by differences in excretion on different collection dates and is probably due to differences in the metabolic state. Hence the determination of 3-methylhistidine/creatinine ratio in single voidings is sufficient even in low-birth-weight infants. In our collective the mean 3-methylhistidine/creatinine ratio for healthy, well-growing low-birth-weight infants (n = 21) was 19.6 +/- 2.3 mumol/mmol. Infants with stagnating or decreasing weight (n = 5) showed 3-methylhistidine/creatinine ratios clearly above that of the normal group.

Body Weight↗
PubMed1987

[1981-1983 breast feeding studies of 1,500 mothers in Dortmund and Haltern. I. Collectives studied and rates of breast feeding in the maternity ward].

Rates of breast-feeding were studied in collectives of 998 mothers (Dortmund) and 500 mothers (Haltern) in two large maternity wards encouraging breast-feeding. In both hospitals the collectives were representative for the population in the surrounding region. Mothers were asked to take part in the study as they were admitted. Response rates were 99%. Age and parity of mothers in Dortmund were in agreement with population statistics, whereas in the Haltern collective there was a smaller proportion of younger mothers. The collective in Haltern had a slight edge with respect to social background. The different types of delivery had the same percentages in both wards. Birthweight was on the average 100 g higher in Haltern neonates. There were no differences in mean length. In both wards feeding on demand was practised during the rooming-in period during daytime, whereas at night infants were bottle-fed on demand in the infant's room. In Haltern supplementary formula feeding was offered more liberally. In Dortmund 92%, in Haltern 97% of the mothers tried to breast-feed; only 5% and 2% respectively were unsuccessful. Mothers who did not want to breast-feed (8% and 3% respectively) rarely mentioned relevant obstacles as a reason for their decision. On discharge 80-90% of the mothers were breast-feeding, with only about one half of them fully breast-feeding. Caesarean section was hardly detrimental to initiation of breast-feeding, but often to success.

Adult↗
PubMed1987

[Breast feeding studies 1981-1983 in 1,500 mothers in Dortmund and Haltern. III. Rates of breast feeding and duration of breast feeding in the first half year].

With two collectives of mothers from the large maternity wards in Dortmund (n = 998) and Haltern (n = 500) breast-feeding patterns were studied prospectively after dismissal. 95 and 93% of initially breast-feeding mothers kept simple protocols of duration and intensity of breast-feeding. 20 and 13% respectively of the breast-feeding mothers in Dortmund and Haltern stopped breast-feeding within 3 days following discharge, only 2 and 6% respectively of all mothers fully breast-fed for a period of a months as recommended. Already from the beginning of the 2nd month some mothers introduced (unnecessarily) juices as Beikost. Reasons given by the mothers for termination of breast-feeding were mostly connected with problems concerning the mother (50%) and nursing problems (35%). Statistical analysis (Cox proportional hazards model) revealed that the mothers' age (less than 25 years), low educational level, bad breast-feeding experience and use of a pump significantly reduce duration of breast-feeding. Promotion and support of breast-feeding is urgently needed especially during the first weeks after birth and with inexperienced, young and less educated mothers.

Breast Feeding↗
PubMed1987

[1981-1983 breast feeding studies of 1,500 mothers in Dortmund and Haltern. II. Volume of breast milk in the maternity ward].

In two large maternity wards encouraging breast-feeding, breast-milk volumes (weighing of the baby before and after each feeding) and weight development of the infants were determined until dismissal. On days 2, 3 and 4, 20-30%, 60-70%, and 80-90% of the mothers, respectively, produced milk. The largest increase in milk volume ("Einschuss") usually took place between days 3 and 4. Milk volume increased from an average of 150-180 ml on day 4 to 270-300 ml on day 6. Development of milk production was independent of type of delivery; however, the usual delay of one day following caesarean section was not made up for until discharge. Fully breast-feeding mothers produced on the average the same amounts of milk as mothers at the turn of the century. Throughout their stay in the maternity ward, mothers with good breast-feeding experience produced more milk than those with bad or without any breast-feeding experience. Nursing all infants at fairly regular intervals during the day and at night is recommended in order to achieve that as many mothers as possible are fully breast-feeding on discharge. Comparing energy intake and weight development between groups of fully, partially and non breast-fed infants suggested a better utilization of breast-milk.

Body Weight↗
PubMedDate not supplied

[Administration of creatine and creatinine with breast milk and infant milk preparations].

Creatine and creatinine intake can cause increased urinary creatinine excretion. To estimate the contribution of diet to creatinine excretion in infants, creatine and creatinine were determined in human milk, pasteurized cow's milk and formulas for preterm and term infants. Soy-based formulas did not contain creatine and creatinine. Average concentrations in human milk (creatine 77 [60-100] mumol/l, creatinine 52 [41-65] mumol/l) were markedly lower than in pasteurized cow's milk which contained 598 (476-640) mumol/l creatine and 105 (79-122) mumol/l creatinine. Creatine and creatinine concentrations differed widely in formulas for both preterm and term infants, from 155-559 and 33-174 mumol/l, respectively. The influence of ingested creatine on creatinine excretion should theoretically be negligible. On the other hand, based on known absorption data, creatinine from the diet should increase creatinine excretion in a 3-month-old infant up to an amount in the range of 5.3-28.4% of the endogenous production. Therefore creatinine ingestion should be taken into account when interpreting creatinine excretion in infants.

Creatine↗
PubMedDate not supplied

Height growth of adolescent German boys and girls.

Longitudinal annual height measurements of 46 boys and 47 girls from Dortmund, Germany, are used to derive 10 parameters concerning the adolescent growth spurt of height. Out of three mathematical models applied to our height data, model 1 of Preece and Baines (1978) proved most suitable. Data of mean heights at age 9 and 10 of the boys and girls of this study do not differ from those of another representative cross-sectional study of our institute. The values of the 10 parameters agree with the data of studies from other countries. This work contributes original German data to the international data on adolescent growth spurt of height.

Adolescent↗