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Biomedical subjects

T Wisman

Publications and source records attributed to T Wisman.

5 recordsLinked to original sources

Monitoring at the Instituut voor Epilepsiebestrijding Meer en Bosch.

A requirement for intensive epilepsy monitoring arose from a demand for ictal EEG registration for diagnostic purposes and in the context of pharmacokinetic research. The monitoring facility developed gradually: first conventional EEG equipment was used on the wards, later miniaturized pre-amplifiers were introduced to allow the patient greater freedom, finally a comprehensive specialized monitoring facility was created with its own accommodation. For most clinical and research applications arising in the Institute intensive observation and video monitoring are necessary. The greater reliability, channel capacity and bandwidth of cable telemetry offer considerable advantages over alternative monitoring techniques as radio telemetry. For recording from patients in locations outside the monitoring unit but where restricted mobility is acceptable a combination of telephone telemetry with a local radio link is used. Synchronization of EEG and video images is achieved by various means, depending on the application: split-screen technique, superimposition of EEG on video images or annotating the paper EEG chart with digital time information derived from the video time-date generator. Buffering of EEG signals is also available by means of a computer disk or a shift register. During the development of the system evaluation studies have been performed showing a progressively increasing yield of clinically useful information. At the most recent assessment, 79% of the investigations answered the clinical question addressed, in 65% of instances the findings had consequences for management and in over 25% the decisions resulting from monitoring had long-term therapeutic benefits for the patient.

Automation↗

Evaluation of a simple spike-wave recognition system.

A simple analogue system for recognition of spike-wave discharges is described. During an evaluation study of 81 h recording from 23 patients the mean error rates were 4.7% false negatives and 5.2% false positives.

Computers, Analog↗

Telemetric EEG and video monitoring in epilepsy.

We report a clinical evaluation of EEG and video monitoring. In 181 consecutive records, the most common clinical indications were differentiation of epileptic and nonepileptic events (99), seizure recordings for locating a possible focus (23), seizure frequency determination (32), and investigation of possible trigger factors (19). Overall, useful information was obtained in 72% and the clinical question was answered in 67% of records. Prolonged EEG and video monitoring is therefore an important diagnostic aid in patients with proven or suspected epilepsy.

Electroencephalography↗

Fluorescent lighting and epilepsy.

Fluorescent tubes flash at twice the mains frequency (100 Hz in Europe). With aging, 50-Hz brightness modulation appears. A survey of tubes used in our institute showed that 42% exhibited brightness modulation up to a depth of 20% or occasionally 30%. The effects of fluorescent lighting on the EEGs of 20 patients with photosensitive epilepsy have been studied. In no patient did the 100-Hz flicker of normally functioning tubes elicit paroxysmal activity. In 8 of 13 subjects sensitive to 50 Hz, IPS paroxysmal discharges were evoked by 50-Hz brightness modulation, but only at modulation depths of 50% or more. It is concluded that as paroxysmal activity could not be elicited by normally functioning tubes nor at those depths of modulation occurring in practice, fluorescent lighting is unlikely to present a hazard to photosensitive patients.

Adolescent↗