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Biomedical subjects

T Wonnacott

Publications and source records attributed to T Wonnacott.

3 recordsLinked to original sources

Female sterilization: can the woman who will seek reversal be identified prospectively?

Demographic socio-economic and decision-making aspects of sterilization and reversal of sterilization were compared in a group of 103 women requesting reversal (RR) and 117 women about to undergo sterilization (S), to determine the practicality of identifying in advance the woman likely to request reversal. The willingness of patients to pay for these procedures and the ethical implications of these decisions were also examined. RR were younger at the first relationship, birth of first child and birth of last child. There were no differences (RR vs S) between the number of full-term pregnancies, living children and therapeutic abortions. The timing of sterilization (puerperal versus interval) did not influence the decision to be reversed. The level of education, partner's level of education and mean family income were lower in the group requesting reversal. Multiple regression analysis revealed three characteristics which were most discriminatory: youth at first birth; lack of spousal support; and failure to choose 'family complete' as a reason for sterilization. The predictability was not strong enough to provide an accurate assessment of the individual woman. RR were of significantly lower socio-economic standing but were more likely to be prepared to pay a large sum of money for the reversal. The ethical implications of this finding are discussed.

Adult↗

Multiple sclerosis after age 50.

When multiple sclerosis (MS) presents late in life (after the age of 50), it frequently gives diagnostic difficulty. In a large MS clinic population (N = 838), 9.4% of the patients had late onset of MS. Slow deterioration of motor function characterized the initial symptoms and subsequent course of this group of older patients. Progression of disability was more rapid than in younger patients. Evoked response studies and CSF electrophoresis were of high diagnostic yield in the older patient group. Reasons for the differing clinical features in the late-onset patients are discussed. We suggest that the age-of-onset criterion for MS be raised to 60 in adequately investigated cases.

Adult↗

Non-medical selection criteria for artificial insemination and adoption.

A survey of Canadian providers of AID was conducted, along with a parallel survey of adoption workers. The questionnaire focused upon non-medical criteria for patient acceptance (for AID and adoption), including acceptance/rejection of single, lesbian, and common-law women, those economically or mentally unable to support children, and those who themselves have or whose partners have criminal records. Further questions concerned decision-making in patient selection, referral of unacceptable patients elsewhere, and the influence if any of legal advice. Most characteristics reflect great disagreement and lack of consensus within the profession. Attitudes towards characteristics may be influenced by the size and form (university vs private) of the practice, as well as by experience with patients with those characteristics. Systematic differences between AID and adoption providers are detailed and explored, as are implications of the study for the development of bioethical thinking and policy making.

Adoption↗