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T YAMAMOTO

Publications and source records attributed to T YAMAMOTO.

At least 37 records · Page 2Linked to original sources

Shunt bilirubin: evidence for two components.

Studies with C(14)-labeled glycine and delta-aminolevulinic acid as heme-bilirubin precursors in man indicate that the early labeled or shunt bilirubin consists of two fractions. Fraction 1 requires 1 to 24 hours for maximum synthesis, is not dependent on marrow erythropoietic heme synthesis, and is possibly of anabolic origin (formed by a direct pathway from heme precursors). Fraction 2 requires 3 to 4 days for maximum production, is dependent on heme synthesis, and probably has its origin in the bone marrow, as a degradation product of red-cell heme.

Amino Acids↗

Some observations on the fine structure of the sympathetic ganglion of bullfrog.

Electron microscope observations of abdominal sympathetic ganglia of American bullfrogs, Rana catesbiana, have demonstrated the presence of specific areas of cytoplasm in the superficial zone of the perikaryon which are devoid of granulated endoplasmic reticulum. These areas are occupied almost exclusively by granules 200 to 400 A in diameter which can be stained intensely with lead hydroxide but faintly with uranyl acetate. Each granule shows subgranular internal structure after the lead staining. Granules of similar properties are found in synapses also, and may be glycogen. From the satellite cell there extends a number of leaf- or finger-like cytoplasmic projections around the root portion of the nerve process. Some of these projections directly cover the surface of the nerve process. Many others, however, are separated from the neuron by a fairly wide interspace. Multivesicular bodies of the neuron are occasionally observed in a configuration which suggests that they are being extruded from the root of the nerve process into the interspace. Filaments about 100 A in thickness are found in the satellite cell cytoplasm. They are arranged more or less parallel to each other and are especially well developed around synapses and nerve fibers.

Animals↗