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Biomedical subjects

T Z Hwang

Publications and source records attributed to T Z Hwang.

4 recordsLinked to original sources
PubMed2000

Fourth branchial cyst presenting with neonatal respiratory distress.

Fourth branchial cysts are quite rare. A neonate with a left lateral neck mass and respiratory distress was found to have a fourth branchial cyst, which was diagnosed with computed tomography and endoscopy. The characteristic computed tomography findings included an air-containing neck cyst, which was located at the anteromedial site of the common carotid artery with mediastinal extension. Endoscopic examination revealed an internal opening at the apex of the pyriform sinus, communicating with the cyst. Total excision of the cyst was performed, and the specimen, which showed ciliated columnar epithelium with a subepithelial lymphoid infiltrate, thyroid follicles, and thymic tissue, histologically confirmed the diagnosis.

Branchioma↗
PubMed1989

[Laryngeal tuberculosis simulating epiglottitis--a case report].

Adult epiglottitis is an otolaryngological emergency. Under proper antibiotic therapy, however, most cases recover rapidly. This is a report of a case in which clinical findings indicated acute epiglottitis, but which showed no improvement with antibiotic therapy when treated by a local medical doctor for three weeks. Following the immediate application of a fiberoptic and microscopic direct laryngoscope with biopsy, an accurate diagnosis was established, i.e. laryngeal tuberculosis. After receiving the appropriate antituberculous therapy for just one week, the patient's symptoms improved dramatically.

Acute Disease↗
PubMedDate not supplied

EBER in situ hybridization differentiates carcinomas originating from the sinonasal region and the nasopharynx.

Epstein-Barr virus (EBV) has a well-established association with nasopharyngeal carcinoma (NPC), while its association with sinonasal carcinoma is still controversial. The role of EBV in sinonasal carcinoma and the potential value of EBER is situ hybridization in differentiating carcinomas originating from these anatomically neighboring regions were investigated. EBER in situ hybridization was applied to detect EBV in the specimens of surgically proved sinonasal carcinoma and the biopsies of carcinoma of the nasopharynx. EBER in situ hybridization was performed on paraffin embedded tissues by using PCR-derived, digoxigenin-labeled EBER-1 DNA probes. EBV was detected in 2 of 31 (6.5%) surgical specimens of sinonasal carcinoma, including 1 keratinizing squamous cell carcinoma and 1 adenocarcinoma. EBV was detected in all of 31 (100%) biopsies of carcinomas of the nasopharynx, including 1 keratining squamous cell carcinoma, 15 nonkeratinizing carcinomas, 14 undifferentiated carcinomas, and 1 adenocarcinoma. The present study does not support the role of EBV in the development of sinonasal carcinoma as does in carcinoma of the nasopharynx. EBER in situ hybridization is a useful adjunct for differentiating carcinomas originating from the sinonasal region and the nasopharynx.

Adenocarcinoma↗