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Biomedical subjects

T von Kreybig

Publications and source records attributed to T von Kreybig.

11 recordsLinked to original sources

[Studies on toxicity and fertility of escin in the rat (author's transl)].

The DL50 of escin was determined after i.p. application. Juvenile male rats were treated with 2X5 mg/kg escin at age 32 days. After they had reached fertility, kidneys, testes and sperm were examined. The high dose of escin used did not affect fertility and a nephrotoxic activity could not be detected either.

Age Factors

[Teratogenic and mutagenic studies with caffeine in the animal experiment].

Principles of teratogenic and mutagenic actions are defined. The recent experimental studies with laboratory animals, and our investigations with caffeine-sodium benzoicum and with soluble coffee in pregnant rats and mice showed no teratogenicity. The results are compared with specific teratogenic effects of cytostatic agents. A teratogenicity of caffeine can be excluded, a mutagenicity in animal experiments can also not be proved.

Abnormalities, Drug-Induced