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Biomedical subjects

Takuya Umemoto

Publications and source records attributed to Takuya Umemoto.

At least 19 recordsLinked to original sources

High-pressure irrigation and gentian-violet application for mediastinitis following replacement of ascending aorta and aortic valve.

Mediastinitis following ascending aortic replacement is intractable and potentially fatal, and the feature is characterized as having both high mortality and morbidity when its causation pathology is methicillin-resistant Staphylococcus aureus (MRSA). Possible treatments for the condition, which include debridement, irrigation, and healthy tissue transposition, often result in failure. We report a case of MRSA mediastinitis after replacement of the ascending aorta and the aortic valve successfully treated by continuous saline lavage and drainage, debridement, high-pressure irrigation, and gentian-violet application, and delayed omental-flap transposition. The application of gentian violet and high-pressure irrigation may provide an additional option to the standard therapy for intractable mediastinitis after ascending aortic replacement.

Aged↗

Abdominal aortic aneurysm in situs inversus totalis.

Situs inversus totalis refers to a mirror-image reversal of the normal position of the internal organs. The recognition of concomitant anomalies, such as in the cardiac, venous, gastrointestinal, and urinary systems, is extremely important because these anomalies may disturb the surgical procedure for the concurrent disease in situs inversus totalis. The authors describe a case of successfully repaired abdominal aortic aneurysm with a false aneurysm of the right external iliac artery in situs inversus totalis. The coexistence of abdominal aortic aneurysm has been seldom encountered. The presence of anatomical anomalies significantly increases operative risk. The surgical management of patients with abdominal aortic aneurysm in situs inversus totalis is discussed.

Aged↗

Revisiting evidence on lung cancer and passive smoking: adjustment for publication bias by means of "trim and fill" algorithm.

Meta-analyses are subject to bias because smaller or non-significant studies are less likely to be published, and most meta-analyses do not consider the effect of publication bias on their results. To assess the true risk, we revisited a famous meta-analysis including 37 studies on lung cancer and passive smoking, and adjusted for publication bias by means of the "trim and fill" algorithm. The adjusted relative risk of lung cancer in non-smokers who lived with a smoker from the 44 studies including the 7 filled ones was 1.19 (95% confidence interval 1.08-1.31, p = 0.0004), and the estimate of excess risk fell from 24 to 19%.

Algorithms↗

Giant renal aneurysm with arteriovenous fistula.

A hypertensive 78-year-old woman was admitted with continuous abdominal pain and nausea and was diagnosed with right giant renal artery aneurysm (RAA; 70 mm in diameter) by means of abdominal computed tomography. Aortography demonstrated huge RAA with arteriovenous fistula visualizing the inferior vena cava at arterial phase. Nephrectomy was performed and the patient has had an uneventful postoperative course.

Aged↗

Intercostal artery pseudoaneurysm due to stab wound.

Intercostal artery pseudoaneurysm is extremely rare, and only six cases have been reported in the English literature. We describe a case of intercostal artery pseudoaneurysm due to a stab wound, review the literature, and discuss therapeutic modalities. Intercostal artery pseudoaneurysm is at risk for early rupture, and diagnosis before rupture is mandatory. Although embolization is considered to be a feasible therapeutic method, we would emphasize the significance of the anatomic features of the intercostal arteries: multiple blood supplies into the pseudoaneurysm, such as the anterior and posterior intercostal arteries, and musculophrenic artery.

Adult↗