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Biomedical subjects

Tayfun Kirazli

Publications and source records attributed to Tayfun Kirazli.

11 recordsLinked to original sources

[Aberrant internal carotid artery in the middle ear: a case report].

Aberrant course of the internal carotid artery within the middle ear is a rare condition. Surgical interventions following clinical or radiological misinterpretations may lead to fatal complications. A 23-year-old female patient presented with a hearing impairment of 10-month duration. On otoscopic examination, the left tympanic membrane was intact, but there was a pulsatile lesion in the tympanic cavity, synchronous with the heartbeats. Pure-tone audiometric examination of the left ear showed a unilateral mixed hearing loss, especially in low frequencies. Computed tomography showed protrusion of the internal carotid artery into the middle ear from the lateral and superior aspects of the cochlea. Magnetic resonance imaging and MR-angiography showed a left-sided deviation of the left internal carotid artery near the cochlea, associated with a filling defect. The caliber of the left internal carotid artery was narrower than the right one in the middle ear, and its proximal part was thinner. A diagnosis of aberrant internal carotid artery was made.

Abnormalities, Multiple↗

Bipolar electrodissection tonsillectomy in children.

The purpose of this study was to compare bipolar electrodissection tonsillectomy with traditional cold dissection tonsillectomy in the pediatric population. Forty children with recurrent tonsillitis and/or obstructive symptoms were included in the study. The study population was randomly divided into two groups, and the two techniques were compared with regard to operative time, intraoperative and postoperative bleeding and postoperative pain. There were 23 children in the bipolar electrodissection tonsillectomy group (mean age, 8.1 years; range, 5-12 years), and 17 children in the cold dissection tonsillectomy group (mean age, 6.7 years; range, 5-12 years). The average operative times were 15.2+/-8.5 min for bipolar electrodissection tonsillectomy and 29.06+/-13.5 min for cold dissection tonsillectomy (P < 0.05). The blood loss in bipolar electrodissection tonsillectomy and cold dissection tonsillectomy was 5.0+/-4.2 ml and 32.1+/-11.3 ml, respectively (P < 0.05). Postoperative hemorrhage was not observed. Bipolar electrodissection tonsillectomy was less painful the first 30 min postoperatively (P < 0.05). Bipolar electrodissection tonsillectomy in children is a useful technique, with results comparable to traditional cold dissection tonsillectomy.

Airway Obstruction↗

Hearing results after primary cartilage tympanoplasty with island technique.

OBJECTIVE: Because of its rigid quality, cartilage is the grafting material of choice in advanced pathologies, such as adhesive processes or recurrent perforations. However, the use of such a rigid material in tympanic membrane reconstruction causes controversies as to the audiologic aspect. The purpose of this study was to assess overall and frequency-specific hearing results after primary cartilage tympanoplasty with island technique in comparison to the hearing results after primary tympanoplasty with temporalis muscle fascia. STUDY DESIGN AND SETTING: This study was a retrospective review of selected cases between 1999 and 2002. Primary cases with intact ossicular chain, normal middle ear mucosa, and subtotal perforation of the tympanic membrane were included in the study. Fifteen patients were in the cartilage group, whereas 10 patients were in the fascia group. Preoperative and postoperative air-bone gaps at the frequencies of 0.5, 1, 2, and 4 kHz were compared. RESULTS: Both groups were statistically similar on the aspect of the severity of middle ear pathology and the preoperative hearing levels. Mean postoperative gains in air-bone gap were 11.9 dB for the cartilage group and 11.5 dB for the fascia group. There were no statistically significant differences in the postoperative frequency-specific gains in air-bone gap between the 2 groups. CONCLUSIONS: Although cartilage is the ideal grafting material in problem cases, its comparable acoustic properties, especially in the form of cartilage island, to those of fascia will allow a more liberal application in less severe cases, in which functional outcome is more essential.

Adolescent↗

[Pulsatile tinnitus as the presenting symptom of dural arteriovenous fistula in two cases].

Pulsatile tinnitus associated with normal otoscopic findings may present as the only sign of a potentially life-threatening serious disease such as a dural arteriovenous fistula (dAVF) of the transverse or sigmoid sinus. If left untreated, dAVFs may lead to focal neurologic symptoms, intracranial hypertension, or hemorrhage, and finally to death. We report two cases of dAVF presenting with pulsatile tinnitus. Following diagnosis, both patients underwent transarterial embolization, after which their symptoms resolved.

Arteriovenous Fistula↗

Facial nerve neuroma: clinical, diagnostic, and surgical features.

Facial nerve neuromas are uncommon benign tumors. The diversity of tumor locations and their proximity to vital neurovascular structures create a variety of clinical situations, and the management strategy for each case differs. Two cases with tumors located at different sites and associated with different clinical presentations are discussed in terms of diagnosis and management.

Case Reports↗

Jugular bulb diverticula: clinical and radiologic aspects.

OBJECTIVE: This study was performed to determine the clinical presentation of jugular diverticulum and its relevance with the extension of the lesion. STUDY DESIGN: The records and high-resolution CT scans of 1474 patients, with otologic symptoms or related clinical findings, were evaluated retrospectively. In 17 cases in which CT scans revealed the presence of jugular diverticulum, sensorineural symptoms were evaluated with respect to a reference line, perpendicular to the basal turn of the cochlea and tangent to the vestibule in axial CT scan images. RESULTS: When the extension of jugular diverticulum was posterior to the reference line, sensorineural symptoms with vertigo were dominant in most patients (72.7%) in this group. On the other hand, for the patients with anterior-extending jugular diverticulum, sensorineural symptoms without vertigo were detected in 50% of patients, whereas 33.3% had sensorineural symptoms with vertigo. CONCLUSION: This study revealed a relationship between the extension of jugular diverticulum and clinical symptoms. However, this relationship lacks statistical evidence because of the limited number of patients.

Adult↗

The comparison of an empiric proton pump inhibitor trial vs 24-hour double-probe Ph monitoring in laryngopharyngeal reflux.

Laryngopharyngeal reflux (LPR), which is defined as the backflow of gastric contents into the upper aerodigestive tract, is a relatively common disorder. However, its diagnosis still poses many problems. Twenty-four-hour double-probe pH monitoring is currently the diagnostic test of choice, but it has many disadvantages. Thus, an empiric trial of antireflux therapy has been suggested as an alternative method for diagnosis. The purpose of this article is to evaluate the validity of this alternative method in the management of LPR. The study group consisted of 36 patients with symptoms and physical findings suggesting LPR. The control subjects were 23 healthy adults. Twenty-four-hour double-probe pH monitoring was performed both in the study group and the control group, and the results were compared. In addition, the symptoms and physical findings in the study group was scored by the modified reflux symptom index (MRSI) and reflux finding score (RFS) at four intervals: before the start of therapy and at the second, fourth and sixth months of the therapy. The results of the 24-hour double-probe pH monitoring showed no significant difference between the study and the control groups (p>0.05). In the study group, the MRSI before the therapy was 13.6+/-4.4. This index improved significantly to 4.3+/-1.9 at the second month; to 1.5+/-0.6 at the fourth month, and to 0.5+/-0.2 at the sixth month of the therapy (p<0.05). The RFS before the start of the therapy was 14.8+/-3.8; and it improved significantly to 7.7+/-3.8 at the second month; to 4.5+/-2.3 at the fourth month, and to 1.4+/-0.9 at the sixth month of the therapy (p<0.05). The significant improvement in the MRSI and the RFS during the course of proton pump inhibitor therapy relates the patients' symptoms and physical findings to LPR. This implies the validity of the method, not only in the treatment of LPR, but in the diagnosis of this disorder, as well. Unfortunately, 24-hour double-probe pH monitoring has failed to differentiate LPR patients from healthy individuals.

2-Pyridinylmethylsulfinylbenzimidazoles↗

[Landau-Kleffner syndrome (acquired epileptic aphasia)].

Landau-Kleffner syndrome is characterized by a complex group of symptoms including deterioration in language skills, seizures, and abnormal electroencephalography findings. A six-year-old male patient had aphasia for three years and generalized tonic-clonic epileptic seizures for two years. Pure-tone audiometry and auditory brain-stem response audiometry findings were normal. He had verbal auditory agnosia rather than true aphasia. Cranial computed tomography and magnetic resonance imaging studies did not show any abnormal findings. Single-photon emission computed tomography showed hypoperfusion in the right hemispheric temporal lobe. Despite treatment with corticosteroids and intravenous immunoglobulins, multiple exacerbations were interspersed in a four-year follow-up period.

Agnosia↗

[Temporal bone CT and MRI in cochlear implant candidates].

PURPOSE: Hearing can be restored by cochlear implantation in patients with sensorineural hearing loss, who have a normal seventh cranial nerve. The aim of imaging in cochlear implant candidates is to determine the etiology of the hearing loss, congenital malformations and variations that may cause difficulty during the operation, patency of the cochlea and the presence of the seventh, cranial nerve. The aim of this study is to review the literature and to discuss the imaging findings that may affect the type and success of the operation. MATERIALS AND METHODS: 33 cochlear implant candidates, who underwent high resolution computed tomography, were included in the study. High resolution fast spin echo T2 weighted and constructive interference in steady state sequences were performed in 23 patients with a 1.5 Tesla magnetic resonance unit. RESULTS: Computed tomography and magnetic resonance imaging were normal in 16 patients. Unilateral or bilateral labyrinthine ossification was detected in 4 patients. Variations of the temporal bone, congenital malformations, sequelae of chronic otitis and trauma were detected in 13 patients. Cochlear implantation was performed in 5 patients. Operative difficulty, complications and postoperative outcome were noted in these 5 patients. CONCLUSION: High resolution computed tomography and magnetic resonance images obtained by high resolution T2 weighted fast spin echo sequence and constructive interference in steady state sequence help the surgeon in planning the operation and predict potential complications in cochlear implant candidates.

Adolescent↗

[Laser posterior cordectomy in bilateral vocal cord paralysis].

OBJECTIVES: We evaluated the functional results of laser posterior cordectomy with respect to respiration, phonation, and deglutition. PATIENTS AND METHODS: Unilateral laser posterior cordectomy was performed in nine patients (7 women, 2 men; mean age 56 years; range 46 to 61 years) with bilateral vocal cord paralysis. Postoperatively, respiration, deglutition, and phonation were evaluated with the use of an exercise tolerance scale, the Pearson scale, and wavelet analysis, respectively. The mean follow-up period was 14.2 months. RESULTS: Respiration was satisfactory in eight patients. Of these, four patients had excellent, and four patients had good exercise tolerance. The procedure resulted in success without tracheotomy in four patients. No deglutition or aspiration problems developed. Of eight patients with satisfactory respiration, voice quality remained unchanged in six patients, whereas an improved voice quality was noted in two patients who received postoperative phoniatric rehabilitation. CONCLUSION: Laser posterior cordectomy for the treatment of bilateral vocal cord paralysis resolves respiration problems, it restores phonation and deglutition functions, as well.

Deglutition↗