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Terry T Yoshizumi

Publications and source records attributed to Terry T Yoshizumi.

7 recordsLinked to original sources

Optimized radiographic spectra for small animal digital subtraction angiography.

The increasing use of small animals in basic research has spurred interest in new imaging methodologies. Digital subtraction angiography (DSA) offers a particularly appealing approach to functional imaging in the small animal. This study examines the optimal x-ray, molybdenum (Mo) or tungsten (W) target sources, and technique to produce the highest quality small animal functional subtraction angiograms in terms of contrast and signal-difference-to-noise ratio squared (SdNR2). Two limiting conditions were considered-normalization with respect to dose and normalization against tube loading. Image contrast and SdNR2 were simulated using an established x-ray model. DSA images of live rats were taken at two representative tube potentials for the W and Mo sources. Results show that for small animal DSA, the Mo source provides better contrast. However, with digital detectors, SdNR2 is the more relevant figure of merit. The W source operated at kVps >60 achieved a higher SdNR2. The highest SdNR2 was obtained at voltages above 90 kVp. However, operation at the higher potential results in significantly greater dose and tube load and reduced contrast quantization. A reasonable tradeoff can be achieved at tube potentials at the beginning of the performance plateau, around 70 kVp, where the relative gain in SdNR2 is the greatest.

Algorithms↗

Optimization of multiplanar reformations from isotropic data sets acquired with 16-detector row helical CT scanner.

Institutional review board approval and waiver of consent were obtained for the patient component of this retrospective HIPAA-compliant study. By using an anthropomorphic phantom and metal oxide semiconductor field effect transistor detectors, radiation dose was determined for one eight-detector row and two 16-detector row computed tomographic (CT) protocols. A custom phantom was scanned by using the three protocols to identify isotropy. Contrast-to-noise ratios (CNRs) were determined for the same protocols by using a third phantom. Seven patients had undergone isotropic 16-detector row CT of the abdomen and pelvis. Anonymized coronal reformations at various thicknesses were ranked qualitatively by three radiologists. Effective dose equivalents were similar for the eight- and 16-detector row protocols. When transverse and coronal reformations of data acquired in the custom phantom were compared, coronal reformations obtained with the 16-detector row and 0.625-mm section thickness protocol were found to be nearly identical to the transverse image for all sets of line pairs. CNRs were consistently highest on 5-mm-thick coronal reformations (CNR range, 1.2-3.3). For qualitative assessment, 2- and 3-mm-thick coronal reformations were consistently preferred.

Adult↗

Radiation dose to the female breast from 16-MDCT body protocols.

OBJECTIVE: The objective of our study was to determine the radiation dose to the female breast from current 16-MDCT body examinations. MATERIALS AND METHODS: Metal oxide semiconductor field effect transistor (MOSFET) detectors were placed in four quadrants of the breast of a female-configured anthropomorphic phantom to determine radiation dose to the breast. Imaging was performed on a 16-MDCT scanner (LightSpeed, GE Healthcare) using current clinical protocols designed to assess pulmonary embolus (PE) (140 kVp, 380 mA, 0.8-sec rotation, 16 x 1.25 mm collimation), appendicitis (140 kVp, 340 mA, 0.5-sec rotation, 16 x 0.625 mm collimation), and renal calculus (140 kVp, 160 mA, 0.5-sec rotation, 16 x 0.625 mm collimation). RESULTS: Radiation dose to the breast ranged from 4 to 6 cGy for the PE protocol and up to 1-2 cGy in the inferior aspect of the right breast and lateral aspect of the left breast for the appendicitis protocol. The renal calculus protocol yielded less than 150 microGy absorbed breast dose. CONCLUSION: Current clinical chest and abdomen protocols result in vairable radiation doses to the breast. The magnitude of exposure may have implications for imaging strategies.

Breast↗

Comparative scatter and dose performance of slot-scan and full-field digital chest radiography systems.

PURPOSE: To evaluate the scatter, dose, and effective detective quantum efficiency (DQE) performance of a slot-scan digital chest radiography system compared with that of a full-field digital radiography system. MATERIALS AND METHODS: Scatter fraction of a slot-scan system was measured for an anthropomorphic and a geometric phantom by using a posterior beam-stop technique at 117 and 140 kVp. Measurements were repeated with a full-field digital radiography system with and without a 13:1 antiscatter grid at 120 and 140 kVp. For both systems, the effective dose was measured on posteroanterior and lateral views for standard clinical techniques by using dosimeters embedded in a female phantom. The effective DQEs of the two systems were assessed by taking into account the scatter performance and the DQE of each system. The statistical significance of all the comparative differences was ascertained by means of t test analysis. RESULTS: The slot-scan system and the full-field system with grid yielded scatter fractions of 0.13-0.14 and 0.42-0.48 in the lungs and 0.30-0.43 and 0.69-0.78 in the mediastinum, respectively. The sum of the effective doses for posteroanterior and lateral views for the slot-scan system (0.057 mSv +/- 0.003 [+/- standard deviation]) was 34% lower than that for the full-field system (0.086 mSv +/- 0.001, P < .05) at their respective clinical peak voltages (140 and 120 kVp, respectively). The effective DQE of the slot-scan system was equivalent to that of the full-field system in the lung region but was 37% higher in the dense regions (P < .05). CONCLUSION: The slot-scan design leads to marked scatter reduction compared with the more conventional full-field geometries with a grid. The improved scatter performance of a slot-scan geometry can effectively compensate for low DQE and lead to improved image quality.

Phantoms, Imaging↗

Optimization of eight-element multi-detector row helical CT technology for evaluation of the abdomen.

PURPOSE: To evaluate protocols for abdominal imaging with an eight-element multi-detector row computed tomographic (CT) scanner. MATERIALS AND METHODS: An eight-element helical CT scanner was used to acquire data in two phantoms with four-element (pitch, 0.75 and 1.5; section thickness, 1.25, 2.5, and 5.0 mm) and eight-element (pitch, 0.625, 0.875, 1.35 and 1.675; section thickness, 1.25 and 2.5 mm) protocols. One phantom was used for low-contrast detectability and streak artifact; the other, for high-contrast performance. Protocols included near constant radiation dose (140 kV and varied tube current, confirmed by using the above protocols to scan a dedicated radiation dose phantom). Data were analyzed by three blinded readers for streak artifacts, contrast-to-noise ratio, and z-axis resolution (contrast-transfer function). Statistical analysis included studentized range tests. RESULTS: Contrast-to-noise ratios for four and eight elements were not consistently different. Qualitative evaluation for streak artifacts revealed fewer artifacts for all eight-element 1.25-mm-thick section protocols, as compared with eight-element 2.5-mm protocols. All eight-element 2.5-mm protocols except that with 27.0 mm per rotation had fewer streak artifacts than did four-element protocols (P =.02-.04). Contrast-transfer functions along the z axis for eight-element protocols were better than those for four-element protocols, demonstrating improved z-axis resolution (P <.05). CONCLUSION: Images acquired at eight sections per rotation demonstrated no sacrifice of contrast-to-noise ratio, improved z-axis resolution, and fewer streak artifacts, even when radiation dose was similar to that for four-element CT.

Artifacts↗

Single versus multi-detector row CT: comparison of radiation doses and dose profiles.

RATIONALE AND OBJECTIVES: The purpose of this study was twofold: (a) to compare the radiation dose profile between computed tomography (CT) with a single detector row (SD) and with a multi-detector row (MD) and (b) to compare specific organ doses between SD CT and MD CT. MATERIALS AND METHODS: Thermoluminescent dosimeters placed within a 32-cm-diameter cylindrical phantom were used to measure and compare dose profiles from one SD CT scanner and from one MD CT scanner. SD CT scanning parameters were 210 mA, 140 kVp, pitch of 1.0, 5-mm section thickness, and 0.8-second gantry rotation speed. MD CT scanning parameters were 130 mA, 140 kVp, pitch of 0.75, 4 x 5-mm section thickness, 15-mm table feed, and 0.8-second gantry rotation speed. To plot radiation dose profile, doses were measured both in the imaging plane and in the area adjacent to the imaging plane. The resultant data were normalized to achieve constant image noise between MD CT and SD CT. Direct doses to individual organs from primary and scattered radiation were measured with an anthropomorphic phantom containing thermoluminescent dosimeters and with a standard pelvic imaging protocol for both MD CT and SD CT. RESULTS: MD CT resulted in a dose profile approximately 27% higher than that from SD CT in the plane of imaging (8.0 vs 6.3 mGy) and 69% higher adjacent to the plane of imaging (6.8 vs 4.0 mGy). The individual doses to the kidneys, uterus, ovaries, and pelvic bone marrow were 92%-180% higher with MD CT than with SD CT. CONCLUSION: With image noise constant between SD CT and MD CT, the radiation dose profile both inside and outside the plane of imaging was higher with MD CT than with SD CT. Organ dose also was higher with MD CT than with SD CT. This difference should be accounted for in the design of MD CT protocols, especially as MD CT technology becomes more widely available for clinical use.

Female↗