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Biomedical subjects

Th Leibecke

Publications and source records attributed to Th Leibecke.

2 recordsLinked to original sources

[Liver tumor ablation].

Minimal-invasive techniques for ablation of primary and secondary hepatic tumors gain increasingly clinical importance. This is especially true since surgical resection and classic chemotherapy is successful only in a limited number of patients. Local ablative methods incorporate chemo- (percutaneous alcohol instillation, transarterial chemoembolization), thermo- (radiofrequency-, laser-, microwave-, cryoablation, high intensive focused ultrasound) and radio-ablative techniques (interstitial brachytherapy, selective internal radiotherapy). Regarding their implementation and specific effects these methods are varying widely, nevertheless all of them have a high therapeutical efficacy together with a low complication rate in common-correct application presumed. The knowledge on specific indications and contraindications is crucial to implement these methods into multimodality therapy concepts.

Brachytherapy↗

Development of a cryo-device for minimal-invasive application under MRI-control.

This paper describes the development of a cryo-device for the treatment of tumors. The probes are intended to form an iceball inside of an organ, e.g. the liver, to destroy degenerated cells. After successful preliminary tests and the development and construction of several probes, the emphasis is now being placed on the realization of a complete device prototype which will enable clinical studies to be carried out. Important for the functionality of the device is an integrated temperature sensor inside the probes. The device may also be used for cryo-analgesic purposes in pain treatment.

Animals↗