Biomedical subjects

Theodore P Beauchaine

Publications and source records attributed to Theodore P Beauchaine.

17 recordsLinked to original sources

PubMed2007

Patterns of psychopathology in the families of children with conduct problems, depression, and both psychiatric conditions.

Comorbid conduct problems (CPs) and depression are observed far more often than expected by chance, which is perplexing given minimal symptom overlap. In this study, relations between parental psychopathology and children's diagnostic status were evaluated to test competing theories of comorbidity. Participants included 180 families with an 8-12-year-old child diagnosed with CPs, depression, both conditions, or neither condition. Although no single theory of comorbidity was supported fully, evidence suggested that CPs and depression may be inherited separately. Paternal antisocial characteristics and maternal depression provided independent prediction of both child depression and CPs. However, paternal antisocial behavior moderated the effect of maternal depression on CPs. For children with antisocial fathers, CPs were observed regardless of maternal depression levels. In contrast, a strong relation was observed between CPs and maternal depression for children without antisocial fathers.

Antisocial Personality Disorder↗

PubMed2006

Polyvagal Theory and developmental psychopathology: emotion dysregulation and conduct problems from preschool to adolescence.

In science, theories lend coherence to vast amounts of descriptive information. However, current diagnostic approaches in psychopathology are primarily atheoretical, emphasizing description over etiological mechanisms. We describe the importance of Polyvagal Theory toward understanding the etiology of emotion dysregulation, a hallmark of psychopathology. When combined with theories of social reinforcement and motivation, Polyvagal Theory specifies etiological mechanisms through which distinct patterns of psychopathology emerge. In this paper, we summarize three studies evaluating autonomic nervous system functioning in children with conduct problems, ages 4-18. At all age ranges, these children exhibit attenuated sympathetic nervous system responses to reward, suggesting deficiencies in approach motivation. By middle school, this reward insensitivity is met with inadequate vagal modulation of cardiac output, suggesting additional deficiencies in emotion regulation. We propose a biosocial developmental model of conduct problems in which inherited impulsivity is amplified through social reinforcement of emotional lability. Implications for early intervention are discussed.

Adaptation, Physiological↗

PubMed2006

Autonomic correlates of attention-deficit/hyperactivity disorder and oppositional defiant disorder in preschool children.

Numerous studies have revealed autonomic underarousal in conduct-disordered adolescents and antisocial adults. It is unknown, however, whether similar autonomic markers are present in at-risk preschoolers. In this study, the authors compared autonomic profiles of 4- to 6-year-old children with attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD; n = 18) with those of age-matched controls (n = 20). Children with ADHD and ODD exhibited fewer electrodermal responses and lengthened cardiac preejection periods at baseline and during reward. Although group differences were not found in baseline respiratory sinus arrhythmia, heart rate changes among ADHD and ODD participants were mediated exclusively by parasympathetic withdrawal, with no independent sympathetic contribution. Heart rate changes among controls were mediated by both autonomic branches. These results suggest that at-risk preschoolers are autonomically similar to older externalizing children.

Attention Deficit Disorder with Hyperactivity↗

PubMed2006

Risk factors for conduct problems and depressive symptoms in a cohort of Ukrainian children.

Potential risk factors for conduct problems and depressive symptoms were tested in a cohort of 10- to 12-year-old Ukrainian children (N = 544, 47.6% male). Risk factors examined were child emotional lability, child attention problems, poor mother-child communication, coercive maternal discipline, maternal depression, and low marital satisfaction. Results indicated that poor mother-child communication was related to conduct problems and depressive symptoms for both boys and girls. In addition, conduct problems and depression were associated with attention problems for boys and with low marital satisfaction for girls. Emotional lability was related specifically to conduct problems, and maternal punishment was related specifically to depressive symptoms.

Attention↗

PubMed2006

Confirmatory factor analyses of DSM-IV Cluster C personality disorder criteria.

Notwithstanding its research and clinical relevance, the dimensionality and validity of the DSM-IV avoidant, dependent, and obsessive-compulsive personality disorders (PDs) criteria is still a largely unexplored topic. The aim of this study was to test the factor structure for DSM-IV Cluster C PD criteria in a sample of 641 consecutively admitted outpatients. Factor analysis results suggested that avoidant, dependent, and obsessive-compulsive PDs share a common latent dimension, and supported the three-factor structure of both observer and self-report ratings of DSM-IV Cluster C PD criteria. The pattern of factor loadings, however, was different from the one expected according to the DSM-IV classification.

Antisocial Personality Disorder↗

PubMed2005

Psychological, autonomic, and serotonergic correlates of parasuicide among adolescent girls.

Although parasuicidal behavior in adolescence is poorly understood, evidence suggests that it may be a developmental precursor of borderline personality disorder (BPD). Current theories of both parasuicide and BPD suggest that emotion dysregulation is the primary precipitant of self-injury, which serves to dampen overwhelmingly negative affect. To date, however, no studies have assessed endophenotypic markers of emotional responding among parasuicidal adolescents. In the present study, we compare parasuicidal adolescent girls (n=23) with age-matched controls (n=23) on both psychological and physiological measures of emotion regulation and psychopathology. Adolescents, parents, and teachers completed questionnaires assessing internalizing and externalizing psychopathology, substance use, trait affectivity, and histories of parasuicide. Psychophysiological measures including electrodermal responding (EDR), respiratory sinus arrhythmia, and cardiac pre-ejection period (PEP) were collected at baseline, during negative mood induction, and during recovery. Compared with controls, parasuicidal adolescents exhibited reduced respiratory sinus arrhythmia (RSA) at baseline, greater RSA reactivity during negative mood induction, and attenuated peripheral serotonin levels. No between-group differences on measures of PEP or EDR were found. These results lend further support to theories of emotion dysregulation and impulsivity in parasuicidal teenage girls.

Adolescent↗

PubMed2005

Mental health of lesbian, gay, bisexual, and heterosexual siblings: effects of gender, sexual orientation, and family.

Self-identified lesbian, gay male, and bisexual (LGB) individuals were recruited via convenience sampling, and they in turn recruited their siblings (79% heterosexual, 19% LGB). The resulting sample of 533 heterosexual, 558 lesbian or gay male, and 163 bisexual participants was compared on mental health variables and their use of mental health services. Multilevel modeling analyses revealed that sexual orientation predicted suicidal ideation, suicide attempts, self-injurious behavior, use of psychotherapy, and use of psychiatric medications over and above the effects of family adjustment. Sexual orientation was unrelated to current psychological distress, psychiatric hospitalizations, and self-esteem. This is the 1st study to model family effects on the mental health of LGB participants and their siblings.

Adult↗

PubMed2005

Mediators, moderators, and predictors of 1-year outcomes among children treated for early-onset conduct problems: a latent growth curve analysis.

Several child conduct problem interventions have been classified as either efficacious or well established. Nevertheless, much remains to be learned about predictors of treatment response and mechanisms of behavioral change. In this study, the authors combine data from 6 randomized clinical trials and 514 children, ages 3.0-8.5 years, to evaluate moderators, mediators, and predictors of outcome. Among other findings, latent growth curve models of mother-report and observational measures of child externalizing behaviors suggested that marital adjustment, maternal depression, paternal substance abuse, and child comorbid anxiety/depression each moderated treatment response. Moreover, critical, harsh, and ineffective parenting both predicted and mediated outcome, with the most favorable responses observed when parents scored relatively low on each construct at intake yet improved during treatment. Implications for treatment nonresponders are discussed.

Age of Onset↗

PubMed2005

Victimization over the life span: a comparison of lesbian, gay, bisexual, and heterosexual siblings.

Lifetime victimization was examined in a primarily European American sample that comprised 557 lesbian/gay, 163 bisexual, and 525 heterosexual adults. Lesbian, gay, and bisexual (LGB) participants were recruited via LGB e-mail lists, periodicals, and organizations; these participants recruited 1 or more siblings for participation in the study (81% heterosexual, 19% LGB). In hierarchical linear modeling analyses, sexual orientation was a significant predictor of most of the victimization variables. Compared with heterosexual participants, LGB participants reported more childhood psychological and physical abuse by parents or caretakers, more childhood sexual abuse, more partner psychological and physical victimization in adulthood, and more sexual assault experiences in adulthood. Sexual orientation differences in sexual victimization were greater among men than among women.

Adolescent↗

PubMed2005

Assessing clinical significance: does it matter which method we use?

Measures of clinical significance are frequently used to evaluate client change during therapy. Several alternatives to the original method devised by N. S. Jacobson, W. C. Follette, & D. Revenstorf (1984) have been proposed, each purporting to increase accuracy. However, researchers have had little systematic guidance in choosing among alternatives. In this simulation study, the authors systematically explored data parameters (e.g., reliability of measurement, pre-post effect size, and pre-post correlation) that might yield differing results among the most widely considered clinical significance methods. Results indicated that classification across methods was far more similar than different, especially at greater levels of reliability. As such, the existing methods of clinical significance appear highly comparable; future directions for clinical significance use and research are discussed.

Data Interpretation, Statistical↗

PubMed2005

A comparison of psychophysiological and self-report measures of BAS and BIS activation.

The behavioral approach (BAS) and behavioral inhibition (BIS) systems are central to theories of both personality and psychopathology, yet agreement on methods of assessing BAS and BIS sensitivity has yet to emerge. We compare the Carver and White (1994) BIS/BAS scales with putative physiological markers of BAS (pre-ejection period [PEP], respiratory sinus arrhythmia [RSA]) and BIS (electrodermal responding) reactivity during reward and extinction among 50 undergraduates. PEP, RSA, and electrodermal activity each responded strongly to one or more task conditions, but correlations with BIS/BAS scores were stronger for measures of affectivity than for any physiological marker. Finally, PEP reactivity was the only autonomic index that responded only to reward. These findings suggest that (a) self-report and physiological measures of BAS and BIS reactivity are independent, and (b) PEP may be superior to RSA as an index of approach motivation.

Adolescent↗

PubMed2003

Taxometrics and developmental psychopathology.

Developmental psychopathologists have criticized categorical classification systems for their inability to account for within-group heterogeneity in biological, etiological. developmental, and cultural influences on behavior. Dichotomizing continuous scores of symptom severity is also inadvisable statistically. Perhaps because of a resulting wariness of categorizing, few explorations into the ontological status of traits or disorders as dimensional versus discrete have been conducted. It is argued here that the limitations of categorizing have little to do with the ontological status of traits and that developmental psychopathologists should be concerned with identifying discrete behavioral syndromes. Common taxometric methods for resolving discrete traits are described, and questions of concern to developmental psychopathologists are outlined that can be addressed through taxometrics studies. These include (a) identifying children who are at risk for future psychopathology, (b) identifying discrete subtypes within current diagnostic classes, (c) locating sensitive periods in the development of discrete pathological traits, (d) discovering moderators of treatment outcome, and (e) elucidating mechanisms of equifinality and multifinality. Although most behavioral traits probably are distributed continuously, identifying those that are discrete will advance the science of developmental psychopathology. Disorders for which taxometric analyses might be applied include anxiety, attention deficit hyperactivity disorder, autism spectrum disorders, conduct problems, depression, and schizophrenia.

Algorithms↗

PubMed2003

Are there really patterns of attachment? Comment on Fraley and Spieker (2003).

Ainsworth's description of attachment patterns in the Strange Situation is one of the best known and most enduring descriptive insights in developmental psychology. Yet attachment theorists have paid little attention to whether ABC classifications represent a true taxonomy or to mechanisms that might produce truly distinct patterns of attachment. This comment focuses on three questions. Does attachment theory require distinct patterns of attachment? How can taxonomic analysis contribute to an understanding of individual differences in attachment security? And are attachment theorists asking the right questions? The authors conclude that attachment theory is indifferent to the structure (taxonomic or dimensional) of individual differences. Nonetheless, taxonomic search methods can make important contributions to attachment study if research is broadened to include secure base behavior in naturalistic settings.

Female↗

PubMed2003

Pseudotaxonicity in MAMBAC and MAXCOV analyses of rating-scale data: turning continua into classes by manipulating observer's expectations.

Taxometric procedures such as mean above minus below a cut and maximum covariance can determine whether a trait is distributed as a discrete latent class. These methods have been used to infer taxonic structure in several personality and psychopathology constructs, often from analyses of rating scale data. This is problematic given (a) well established biases in ratings, (b) the human tendency to think categorically, and (c) implicit typological models of personality and psychopathology among expert raters. Using an experimental method in which the cognitive sets of raters were manipulated as dimensional versus categorical, it is demonstrated that pseudotaxonicity can be created readily with rating scale measures. This suggests that researchers avoid an exclusive reliance on rating scales when conducting taxometrics investigations.

Adult↗

PubMed2002

Cognitive response repertoires to child noncompliance by mothers of aggressive boys.

Cognitive response repertoires to videotaped child noncompliance episodes were examined in mothers of aggressive (MAs) and nonaggressive 4-6-year-old boys. Mothers provided open-ended solutions to three subtypes of child noncompliance under conditions of time pressure, or after they waited for 15 s to consider alternatives. Solutions were coded as assistance/facilitation, coercion, deference, or explanation/clarification. Compared with controls, MAs offered fewer explanation/clarification responses, more coercive responses, and fewer unique solutions during pressured responding. Two to 6 weeks later, mothers were videotaped while participating with their sons in a challenging block building task. Maternal responses to the vignettes predicted conflict escalation during block building, even after rates of concurrent and past child noncompliance were partialled out. Implications for parent-training models are considered.

Adult↗

PubMed2002

A comparison of maximum covariance and K-means cluster analysis in classifying cases into known taxon groups.

Maximum covariance (MAXCOV) is a method for determining whether a group of 3 or more indicators marks 1 continuous or 2 discrete latent distributions of individuals. Although the circumstances under which MAXCOV is effective in detecting latent taxa have been specified, its efficiency in classifying cases into groups has not been assessed, and few studies have compared its performance with that of cluster analysis. In the present Monte Carlo study, the classification efficiencies of MAXCOV and the k-means algorithm were compared across ranges of sample size, effect size, indicator number, taxon base rate, and within-groups covariance. When the impact of these parameters was minimized, k-means classified more data points correctly than MAXCOV. However, when the effects of all parameters were increased concurrently, MAXCOV outperformed k-means.

Cluster Analysis↗

PubMedDate not supplied

A latent structure analysis of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Narcissistic Personality Disorder criteria.

The aim of this study was to examine the latent structure of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), Narcissistic Personality Disorder (NPD) criteria in a group of 641 outpatients. The consecutively admitted outpatients were administered the Structured Clinical Interview for DSM-IV Axis II Personality Disorders, Version 2.0, and the Personality Questionnaire. Both confirmatory and exploratory factor analyses (CFA and EFA, respectively) were used to evaluate whether the NPD criteria measure a single latent trait. Latent class analysis was used to assess the diagnostic accuracy of the individual DSM-IV NPD criteria. Mean above minus below a cut (MAMBAC) and maximum covariance (MAXCOV) taxometric analyses were used to evaluate whether the latent distribution of the DSM-IV NPD features is actually discrete. Both CFA and EFA results showed that the 9 DSM-IV NPD criteria loaded on 2 correlated factors. The latent class analysis results suggested a 3-class solution for NPD criteria; relevant differences in diagnostic efficiency were observed among the NPD criteria. MAMBAC and MAXCOV analyses provided consistent evidence of taxonic (ie, discrete) latent structure for NPD. This study gave only partial support to the validity of the DSM-IV NPD construct. Taxometric analyses indicated that a typological model is appropriate for describing NPD, but CFA and EFA suggested the existence of 2 distinct-albeit correlated-clusters of narcissistic features. As a whole, the DSM-IV criteria discriminated NPD from other personality disorders, but diagnostic accuracy statistics did not replicate the rank order of diagnostic efficiency of NPD criteria proposed by the DSM-IV.

Adult↗