Biomedical subjects

Tian-Xia Qiu

Publications and source records attributed to Tian-Xia Qiu.

7 recordsLinked to original sources

PubMed2006

Effect of bilateral facetectomy of thoracolumbar spine T11-L1 on spinal stability.

Spinal stenosis can be found in any part of the spine, though it is most commonly located on the lumbar and cervical areas. It has been documented in the literature that bilateral facetectomy in a lumbar motion segment to increase the space induces an increase in flexibility at the level at which the surgery was performed. However, the result of bilateral facetectomy on the stability of the thoracolumbar spine has not been studied. A nonlinear three-dimensional finite element (FE) model of thoracolumbar T11-L1 was built to explore the influence of bilateral facetectomy. The FE model of T11-L1 was validated against published experimental results under various physiological loadings. The FE model with bilateral facetectomy was evaluated under flexion, extension, lateral bending and axial rotation to determine alterations in kinematics. Results show that bilateral facetectomy causes increase in motion, considerable increase in axial rotation and least increase in lateral bending. Removal of facets did not result in significant change in the sagittal motion in flexion and extension.

Biomechanical Phenomena↗

PubMed2006

Comparison of kinematics between thoracolumbar T11-t12 and T12-L1 functional spinal units.

The purpose of this study was to compare the kinematics in terms of the locations and loci of instantaneous axes of rotation (IARs) at levels T11-T12 and T12-L1 of thoracolumbar junction (TLJ). The LAR is one of the kinematics characteristics of a functional spinal unit (FSU) in a plane under load. There is little information about loci of IARs in the TLJ. Validated finite element (FE) models of T11-T12 and T12-L1 FSUs were used to determine the locations and loci of IARs in three anatomical planes. In the sagittal plane, the locations and loci of the IARs were located below the intervertebral disc for T11-T12, and situated in the intervertebral disc for T12-L1. In the frontal plane, they were all located around the mid-sagittal plane for T11-T12 and T12-L1. In the transverse plane, they fell in the medio-anterior region of the movable vertebra T11 for T11-T12, and located near the cortical shell of the upper vertebra T12 for T12-L1. These findings may offer an insight to better understanding the kinematics of the human thoracolumbar spine and provide clinically relevant information for the evaluation of spinal stability and functionality of implant devices.

Biomechanical Phenomena↗

PubMed2005

Investigation of thoracolumbar T12-L1 burst fracture mechanism using finite element method.

A finite element model of the T12-L1 motion segment was subjected to dynamic vertical impact to investigate vertebral burst fracture mechanism at the thoracolumbar junction. A rigid ball was directed vertically towards a rigid plate fixed on top of the T12 vertebral body to simulate the axial impact. The results show that upon impact, the T12 vertebra exhibited a vibratory motion. At its maximum compression, the endplates bulged towards their vertebral bodies. The central parts of the endplates adjacent to the nucleus experienced the highest effective stress, and localized stress concentration developed correspondingly within the central parts of the cancellous bone adjacent to the endplates. This appears to confirm the hypothesis that nucleus material is forced to enter the vertebral body, pressurizing it further and squeezing the fat and marrow contents out of the cancellous bone. When the nucleus material enters the vertebral body faster than fat and marrow being expulsed, the vertebral body could burst through the anterior and posterior cortical shell. Upon sudden posterior cortex fracture, the transient fragment encroachment could be further into the spinal canal than the final observed locations, as the fragments are retropulsed to the vertebral body during the bursting process.

Biomechanical Phenomena↗

PubMed2004

Kinematics of the thoracic T10-T11 motion segment: locus of instantaneous axes of rotation in flexion and extension.

The purpose of this study was to determine the locations and loci of instantaneous axes of rotation (IARs) of the T10-T11 motion segment in flexion and extension. An anatomically accurate three-dimensional model of thoracic T10-T11 functional spinal unit (FSU) was developed and validated against published experimental data under flexion, extension, lateral bending, and axial rotation loading configurations. The validated model was exercised under six load configurations that produced motions only in the sagittal plane to characterize the loci of IARs for flexion and extension. The IARs for both flexion and extension under these six load types were directly below the geometric center of the moving vertebra, and all the loci of IARs were tracked superoanteriorly for flexion and inferoposteriorly for extension with rotation. These findings may offer an insight to better understanding of the kinematics of the human thoracic spine and provide clinically relevant information for the evaluation of spinal stability and implant device functionality.

Biomechanical Phenomena↗

PubMed2004

Effects of cervical cages on load distribution of cancellous core: a finite element analysis.

METHODS: The study was designed to analyze the load distribution of the cancellous core after implantation of vertical ring cages made of titanium, cortical bone, and tantalum using the finite element (FE) method. The intact FE model of C5-C6 motion segment was validated with experimental results. RESULTS: The percentage of load distribution in cancellous core dropped by about one-third of the level for the intact model after the cage implantation. The difference among cages made of different materials (or different stiffnesses) was not very obvious. CONCLUSIONS: These results implied that the influence of the cage on the load transfer in the cancellous core is greatly related to the cage's dimensions and position within the intervertebral space. The dimension and position of the cage that least disturb the load distribution in cancellous core could be criteria in cage development.

Cadaver↗

PubMed2003

Validation of T10-T11 finite element model and determination of instantaneous axes of rotations in three anatomical planes.

STUDY DESIGN: A finite element (FE) model of thoracic spine (T10-T11) was constructed and used to determine instantaneous axes of rotation (IARs). OBJECTIVES: To characterize the locations and loci of IARs in three anatomic planes. SUMMARY OF BACKGROUND DATA: The center of rotation is a part of a precise method of documenting the kinematics of a spinal segment for spinal stability and deformity assessments and for implant devices study. There is little information about loci of IARs in thoracic spine. METHODS: A FE model of thoracic spine (T10-T11) was developed and validated against published data. The validated model was then used to determine the locations and loci of IARs in three anatomic planes. RESULTS: Within the validated range, The IARs locations and loci were found to vary with the applied pure moments. Under flexion and extension pure moments, the loci of IARs were tracked anterosuperiorly for flexion and posteroinferiorly for extension with rotation between the superior endplate and the geometrical center of the inferior vertebra T11. Under left and right lateral bending pure moments, the loci were detected to diverge latero-inferiorly from the mid-height of the intervertebral disc, then converge medio-inferiorly toward the geometrical center of the inferior vertebra T11. For axial rotation, the IARs were located between anterior nucleus and anulus and found to diverge in opposite direction latero-posteriorly with increasing left and right axial torque. CONCLUSIONS: The results of IARs would provide further understanding to the kinematics and biomechanical responses of the human thoracic spine, which is important for the diagnosis of disc degeneration and implant study.

Biomechanical Phenomena↗

PubMed2003

Finite element analysis of cervical spinal instability under physiologic loading.

The definition of cervical spinal instability has been a subject of considerable debate and has not been clearly established. Stability of the motion segment is provided by ligaments, facet joints, and disc, which restrict range of movement. Moreover, permanent damage to one of the stabilizing structures alters the roles of the other two. Although many studies have been conducted to investigate cervical injuries, to date there are only limited finite element investigations reported in the literature on the biomechanical response of the cervical spine in these respects. A comprehensive, geometric, nonlinear finite element model of the lower cervical spine has been successfully developed and validated under compression, anterior-posterior shear, and sagittal moments. Injury studies were done by varying each spinal component independently from the validated model. Seven analyses were conducted for each injury simulation (model without ligaments, model without facets, model without facets and ligaments, and model without disc nucleus). Results indicate that the role of the ligaments in resisting anterior and posterior shear and flexion and axial rotation moments is important. Under other physiologic loading (anterior-posterior shear, flexion-extension, lateral bending, and axial rotation), the disc nucleus is responsible for the initial stiffness of the cervical spine. The results also highlight the importance of facets in resisting compression at higher loads, anterior shear, extension, lateral bending, and torsion. The results provide new insight through injury simulation into the role of the various spinal components in providing cervical spinal stability. These findings seem to correlate well with experimental results as well as with common clinical experience.

Cervical Vertebrae↗