Tom Rainey | PubMed Health

PubMed2006

Light scattering study on the size and structure of calcium phosphate/hydroxyapatite flocs formed in sugar solutions.

The formation, flocculation and sedimentation of calcium phosphate particles are among the main physico-chemical reactions that occur during the clarification of cane sugar juice. The mechanisms through which processes occur in juice clarification are still poorly understood. This study (being part of a comprehensive investigation to unravel these mechanisms) reports on the size and structure of calcium phosphate particles and aggregates in water and sugar solutions at 20 degrees C using the small angle laser light scattering technique. The average size of the primary calcium phosphate particles was in the range 10.4+/-1.1 microm to 17.5+/-1.2 microm and the scattering exponents, which describe the structure of the calcium phosphate flocs, varied from 1.97 to 2.76. The flocs formed without flocculant are more compact in water than those formed in sugar solution. The compactness of the flocs was also affected by pH of the solution. This effect has been explained by considering the electrical double layer phenomenon.

Carbohydrates↗

PubMed2003

Developing and pilot testing quality indicators in the intensive care unit.

PURPOSE: To develop and implement a set of valid and reliable yet practical measures of intensive care units (ICU) quality of care in a cohort of ICUs and to estimate, based on current performance, the potential opportunity to improve quality. METHODS: We included 13 adult medical and surgical ICUs in urban community teaching and community hospitals. To monitor performance on previously identified quality measures, we developed 3 data collection tools: the Team Leader, Daily Rounding, and Infection Control forms. These tools were pilot tested, validated, and modified before implementation. We used published estimates of efficacy to estimate the clinical and economic effect of our current performance for each of the process measures: appropriate sedation, prevention of ventilator-associated pneumonia, appropriate peptic ulcer disease (PUD) prophylaxis, appropriate deep venous thrombosis (DVT) prophylaxis, and appropriate use of blood transfusions. RESULTS: Performance varied widely among the 13 ICUs and within ICUs. The median percentage of days in which ventilated patients received therapies that ought to was 64% for appropriate sedation, 67% for elevating head of bed, 89% for PUD prophylaxis, and 87% for DVT prophylaxis. The median rate of appropriate transfusion was 33%. The failure to use these therapies may lead to excess morbidity, mortality, and ICU length of stay. CONCLUSION: To improve quality of care, we must measure our performance. This pilot study suggests that it is feasible to implement a broad set of ICU quality measures in a cohort of hospitals. By improving performance on these measures, we may realize reduced mortality, morbidity, and ICU length of stay.

Cohort Studies↗