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Tomislav Mihaljevic

Publications and source records attributed to Tomislav Mihaljevic.

44 records · Page 3Linked to original sources
PubMed2003

A practical approach to a comprehensive epicardial and epiaortic echocardiographic examination.

OBJECTIVE: More than a decade before the introduction of intraoperative transesophageal echocardiography (TEE), epicardial echocardiography was already in use as a diagnostic imaging modality to assist cardiac surgeons and anesthesiologists with clinical decision making. Although TEE has since become increasingly more popular, epicardial echocardiography may be the most convenient intraoperative imaging technique when TEE probe placement cannot be performed or is contraindicated. The authors developed a comprehensive examination protocol for the intraoperative interrogation of cardiac structures using an epicardial/epiaortic echocardiographic approach. DESIGN: Retrospective analysis of patient's medical records. SETTING: Single-center academic tertiary care hospital. PARTICIPANTS: Patients undergoing cardiac surgery. INTERVENTIONS: A total of 10 echocardiographic views were obtained for imaging cardiac structures, the ascending aorta, and proximal aortic arch. The described imaging planes permit the evaluation of ventricular performance, valvular function, cardiac structural abnormalities, and aortic disease. MEASUREMENTS AND MAIN RESULTS: A comprehensive epicardial/epiaortic echocardiographic examination was performed in 20 patients undergoing cardiac surgery requiring a full sternotomy. The described imaging planes were obtained in all patients in less than 8 minutes (range, 3.5-8 minutes; mean, 5.5 minutes). CONCLUSION: The present manuscript delineates a protocol for performing a comprehensive, intraoperative epicardial/epiaortic echocardiographic examination. Echocardiographic imaging planes of cardiac and aortic anatomy are described. This protocol may be useful for cardiac surgeons and anesthesiologists seeking to use this technique as a cardiac imaging modality that is complementary to TEE.

Aorta↗
PubMed2002

Aortic valve surgery after previous coronary artery bypass grafting with functioning internal mammary artery grafts.

BACKGROUND: Aortic valve surgery after coronary artery bypass grafting (CABG) in the setting of patent pedicled internal mammary artery (IMA) grafts poses a high risk because of the underlying ischemic and valve disease. Unlike mitral valve surgery or CABG, in which aortic clamping (AoX) may be optional, aortic valve surgery uniformly requires AoX unless circulatory arrest is used. Management of the IMA graft in these circumstances has traditionally involved dissection and clamping to prevent regional myocardial warming and cardioplegia "washout" during AoX. An alternative strategy involves avoiding dissection of the IMA, leaving the IMA graft open and establishing moderate-to-deep hypothermia during AoX and cardioplegic arrest. To date, no study has been published documenting the safety and efficacy of the latter practice. METHODS: A total of 94 patients who had patent IMA graft and underwent aortic valve surgery under AoX and cardioplegia between April 1992 and March 2001 were analyzed. The IMA was avoided and left open during AoX, and the patients were cooled systemically (median 20 degrees C). Patients ranged in age from 55 to 90 years (median 73.5 years). Ejection fraction was 15% to 83% (median 50%). Of the patients, 18 (19%) underwent minimally invasive upper hemi-resternotomy. Analysis for predictors of outcome was performed. RESULTS: The operative mortality, perioperative myocardial infarction (MI), and stroke rates were 6.4%, 7%, and 11%, respectively. No significant independent predictors of operative mortality or MI could be identified in the multivariate analysis, although a trend was shown for operative mortality with urgent procedures and patients requiring concomitant surgery of the ascending or arch aorta or aortic root. Advanced age and prolonged cardiopulmonary bypass predicted stroke in the multivariate analysis. There were five (5%) IMA injuries, all occurring during reentry or mediastinal dissection, but none in the subgroup of patients who underwent minimally invasive procedures. All patients survived. CONCLUSIONS: Patients undergoing aortic valve surgery after CABG in the presence of patent IMA represent a potentially high-risk group. Because AoX is almost uniformly required, a decision regarding the management of the IMA pedicle is needed. We have found that leaving the IMA undissected and unclamped is a reasonable strategy, provided that systemic cooling for myocardial protection is established to prevent regional warming and to compensate for cardioplegia washout effect during AoX.

Aged↗
PubMed2002

Echocardiographic evidence of right ventricular remodeling after transplantation.

Right ventricular (RV) failure is a significant source of mortality after cardiac transplantation. The use of RV assist devices (RVAD) as a bridge to recovery has been reported. However, early changes of RV structure and anatomy after RVAD implantation have yet to be described. We report a case of RV failure after transplantation requiring RVAD implantation. After 3 weeks of gradual weaning of inotropic and RVAD support, the device was explanted successfully. Transesophageal echocardiography documents RV hypertrophy and remodeling between RVAD implantation and removal, suggesting a rapid adaptive response of the right ventricle in the presence of pulmonary hypertension.

Adult↗
PubMed2002

Risk factors and management of endocarditis after mitral valve repair.

BACKGROUND AND AIMS OF THE STUDY: The authors' nine-year experience with patients requiring mitral valve reoperations for endocarditis after previous mitral valve repair is reported. METHODS: Between June 1991 and June 2000, 1,275 mitral valve repairs were performed at the authors' institution. During this time, nine patients with prior mitral valve repair presented with mitral valve (non-recurrent) endocarditis requiring surgical correction. Etiology at the initial mitral valve repair was ischemic in four patients (44%), floppy valve in one patient (11%), Libman-Sacks endocarditis in one (11%), irradiation-induced degeneration in one (11%), and endocarditis in two cases (22%). Median patient age was 61 years (range: 36-81 years). Median ejection fraction was 50% (range: 23-70%), and seven patients (78%) presented urgently or emergently. The median time interval between the two procedures was 8.6 months (range: 28 days to 14.3 years). RESULTS: Certain risk factors were identified in these patients, including systemic infections, prosthetic implants in the bloodstream, and subsequent invasive procedures. The mitral valve was re-repaired in one patient (11%), while eight patients (89%) required valve replacement. All required excision of the ring. Hospital mortality was 11% (n = 1). Postoperative complications included perioperative myocardial infarction in two cases (25%), low cardiac output in two (25%), and prolonged ventilatory support in four (50%). There was no perioperative stroke, and no late recurrence of endocarditis. CONCLUSION: The study findings suggest that the incidence of (non-recurrent) endocarditis after mitral valve repair requiring surgical intervention is infrequent. Attempts at re-repair may be successful only in selected patients. Reoperation was accomplished with acceptable morbidity and mortality, and often required mitral valve replacement; however, late results indicated the absence of prosthetic valve endocarditis.

Adult↗
PubMedDate not supplied

Minimally invasive valve surgery: what the pathologist should know.

Minimally invasive approaches in cardiac surgery have emerged as an alternative to standard techniques particularly in patients undergoing valvular surgery. Their established benefits for the patients are likely to cause their widespread use in the future. The purpose of this is to provide an overview of modern minimally invasive approaches in valvular surgery with an emphasis on aspects of the surgery relevant for cardiovascular pathologists.

Heart Valve Diseases↗
PubMedDate not supplied

Management of mild aortic stenosis during coronary artery bypass surgery: an update, 1992-2001.

BACKGROUND: "Prophylactic" aortic valve replacement (AVR) in patients with asymptomatic, mild-to-moderate aortic stenosis (AS) at the time of CABG is controversial. In 1994, we reported our initial experience involving 44 patients and have now updated our series in an attempt to further evaluate outcomes. METHODS: Between January 1992 and July 2001, 100 consecutive patients underwent reoperative AVR following previous CABG. Forty patients had their initial surgery at the Brigham & Women's Hospital (BWH) and 60 patients had their coronary surgery elsewhere. None of the 40 BWH patients had a mean valve gradient greater than 25 mmHg at the time of CABG. RESULTS: The mean time interval from CABG to AVR for the entire group was 9.0 years (range: 1.4-21 years). Overall operative mortality (OM) was 7% including 5 deaths (10.2%) among 49 patients requiring additional CABG at the time of AVR and 2 deaths (3.9%) among 51 patients without additional coronary artery intervention. This OM rate was a notable decrease from our earlier report of 18.2% (P = 0.07). Furthermore, operative mortality decreased progressively from 15.4% in 1992-1993 to 0% in 2000-2001 (P = NS). CONCLUSION: The OM of reoperative AVR following CABG has fallen in recent years. Given the relevance of newer techniques and approaches, it may be reasonable to adopt an expectant management approach in patients with asymptomatic mild-to-moderate AS (i.e., mean systolic gradient less than 25 mmHg) at the time of CABG.

Aged↗