Biomedical subjects

Tracy E Orr

Publications and source records attributed to Tracy E Orr.

3 recordsLinked to original sources

PubMed2003

Posterior thoracic extrapedicular fixation: a biomechanical study.

STUDY DESIGN: In vitro biomechanical testing of thoracic spine specimens using a standardized three-dimensional spine flexibility protocol. OBJECTIVES: To compare the mechanical stability of the intrapedicular and extrapedicular technique for pedicle screw placement. The hypothesis was that extrapedicular screw placement provides an equally rigid construct. SUMMARY OF BACKGROUND DATA: Pedicle screws provide rigid fixation of instabilities in the lumbar and lumbosacral spine. Anatomic considerations and the potential risk of neurologic complications are the main reasons to hesitate using pedicle screws in the thoracic spine. Extrapedicular fixation would allow safer insertion due to an increased distance to the spinal canal. METHODS: Twelve human cadaveric thoracic spines (six intra-, six extrapedicular) were instrumented with the USS system, using computed tomography-based computer navigation to ensure accurate placement. The specimens were tested in flexion-extension, torsion, and lateral bending. The ROM was measured using an optoelectronic system, and the two methods were compared before and after implantation of the USS construct and before and after fatigue testing of the construct. RESULTS: The ROM of the instrumented spine was reduced to less than 50% that of its original ROM. There were no statistically significant differences in the ROM reduction between the intra- and the extrapedicular technique. Cyclic fatiguing of the construct did not significantly increase the ROM. CONCLUSIONS: The extrapedicular technique provides a construct for stabilization of the thoracic spine that is as rigid as the conventional intrapedicular technique, but has the advantage of a safer surgical screw insertion.

Adult↗

PubMed2003

The importance of the endplate for interbody cages in the lumbar spine.

Intervertebral cages in the lumbar spine represent an advancement in spinal fusion to relieve low back pain. Different implant designs require different endplate preparations, but the question of to what extent preservation of the bony endplate might be necessary remains unanswered. In this study the effects of endplate properties and their distribution on stresses in a lumbar functional spinal unit were investigated using finite-element analyses. Three-dimensional finite-element models of L2-L3 with and without a cage were used. An anterior approach for a monobloc, box-shaped cage was modelled. The results showed that inserting a cage increased the maximum von Mises stress and changed the load distribution in the adjacent structures. A harder endplate led to increased concentration of the stress peaks and high stresses were propagated further into the vertebral body, into areas that would usually not experience such stresses. This may cause structural changes and provide an explanation for the damage occurring to the underlying bone, as well as for the subsequent subsidence of the cage. Stress distributions were similar for the two endplate preparation techniques of complete endplate preservation and partial endplate removal from the centre. It can be concluded that cages should be designed such that they rely on the strong peripheral part of the endplate for support and offer a large volume for the graft. Furthermore, the adjacent vertebrae should be assessed to ensure that they show sufficient density in the peripheral regions to tolerate the altered load transfer following cage insertion until an adequate adaptation to the new loading situation is produced by the remodelling process.

Computer Simulation↗

PubMed2002

Factors influencing stresses in the lumbar spine after the insertion of intervertebral cages: finite element analysis.

Intervertebral cages in the lumbar spine have been an advancement in spinal fusion to relieve low back pain. Even though initial stability is accepted as a requirement for fusion, there are other factors. The load transfer and its effect on the tissues adjacent to the cage may also play an essential role, which is not easily detectable with experimental tests. In this study the effects of an intervertebral cage insertion on a lumbar functional spinal unit were investigated using finite element analyses. The influences of cage material, cancellous bone density and spinal loading for the stresses in a functional spinal unit were evaluated. Three-dimensional (3D) finite element models of L2-L3 were developed for this purpose. An anterior approach for a monobloc, box-shaped cage was modelled. Models with cage were compared to the corresponding intact ones. The results showed that inserting a cage increased the maximum von Mises stress and changed the load transfer in the adjacent structures. Varying the cage material or the loading conditions had a much smaller influence than varying the cancellous bone density. The denser the cancellous bone, the more the stress was concentrated underneath the cage, while the remaining regions were unloaded. This study showed that the density of the underlying cancellous bone is a more important factor for the biomechanical behaviour of a motion segment stabilized with a cage, and its eventual clinical success, than the cage material or the applied load. Inserting an intervertebral cage markedly changed the load transfer. The altered stress distribution may trigger bone remodelling and explain damage of the underlying vertebrae.

Adult↗