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Biomedical subjects

Tuncay Hazirolan

Publications and source records attributed to Tuncay Hazirolan.

13 recordsLinked to original sources
PubMed2006

Complex venous anomalies: magnetic resonance imaging findings in a 5-year-old boy.

We report magnetic resonance imaging (MRI) findings of a very unusual venous anomaly case. A 5-year-old boy who had surgical repair of coarctation of the thoracic aorta was referred to our department for evaluation of an enlarged venous structure anterior to the aorta, which had been noted during the surgery. Contrast enhanced dynamic MRI revealed partial anomalous pulmonary venous return to the left azygos vein, double inferior and superior vena cava with the left azygos continuation of the left superior vena cava. The recognition of venous anomalies allows correct planning of surgical and interventional procedures. MRI is a valuable imaging tool providing detailed anatomical information.

Azygos Vein↗
PubMed2006

Does 16-MDCT angiography scanning direction affect image quality of coronary artery bypass grafts and the native coronary arteries?

To assess the impact of scanning direction on the image quality of coronary artery bypass grafts (CABGs), native coronary arteries (NCAs) were examined by electrocardiographically (ECG) gated 16-row multidetector computed tomography (16-MDCT). Eighty-two patients with 209 grafts were studied by 16-MDCT. Forty-one patients with 111 grafts were scanned craniocaudally. Forty-one patients with 98 grafts were scanned caudocranially. CABG, native coronary arteries were examined in four (proximal, middle, distal, distal anastomoses), three (proximal, middle, distal) segments, respectively. Subjective image quality on a four-point scale was calculated for segments. Scores of groups were compared. Results Image quality scores of proximal, distal segments of the right coronary artery (RCA) were better in caudocranially scanned group (P<0.05). When we subgrouped patients according to initial heart rates (IHR) (group 1, <65 beats/min; group 2, > or =65 beats/min), there was no statistical significance between image quality scores of coronary arteries, CABG when IHR was <65 beats/min in groups regardless of scanning direction. Scores of anastomotic segment of CABG to RCA, middle segments of circumflex coronary artery, proximal and distal segments of RCA in caudocranially scanned group were better when the IHR is > or =65 beats/min compared with the craniocaudally scanned group. When the IHR of the patient is > or =65 beats/min, performing ECG-gated 16-MDCT angiography in the caudocranial direction provides better image quality for evaluation of coronary arteries and CABGs.

Adult↗
PubMed2006

Vascular malformations in the extremities: emphasis on MR imaging features that guide treatment options.

Vascular malformations can be classified into high-flow arteriovenous malformations (AVM) and low-flow venous or lymphatic malformations (VM/LM). VMs and LMs have the ability to cross multiple tissue boundaries. Not only is subcutaneous tissue often involved, but multiple muscle groups, tendons, bone cortex and bone marrow are also not uncommonly violated. Magnetic resonance imaging (MRI) provides valuable information for the assessment and treatment of malformations. Firstly, MRI can characterize the flow pattern of these malformations to guide treatment towards trans-arterial embolization for AVMs and percutaneous embolization for low flow malformations. MRI is essential to define the anatomic extent and involvement of various tissue layers (a distinct advantage over ultrasound), and to correlate treatable components of the malformation with patient symptoms. Treatment is decided by the need to alleviate clinical symptoms, and is dependent on the extent of the malformation as defined by MRI. We present MRI features of vascular malformations to demonstrate the potential spectrum of involvement of these lesions, illustrating the value of MRI in treatment planning.

Arteriovenous Malformations↗
PubMed2006

Subcutaneous venous port implantation in adult patients: a single center experience.

PURPOSE: To present the midterm follow-up results of subcutaneous venous chest ports in adult patients. MATERIALS AND METHODS: Between January 2001 and November 2005, 476 subcutaneous venous chest ports were placed in 472 adult patients. Five patients underwent port implantation twice. All the ports had single lumen catheters. The procedures were performed under intravenous sedation as well as local anesthesia. All ports were placed on the anterior chest wall, except one, which was placed on the trapezius muscle. RESULTS: The technical success rate was 99.8%. The procedure- related minor complication rate was 0.63% (total: 3 cases; 1 hematoma during local anesthesia application, and 2 early hematomas) and there were no major complications. Mean duration of catheter usage was 376 days (total: 178,997 catheter days; range: 2 to 1522 catheter days). Late complications occurred at a rate of 10.7% (51 cases). Among those 51 cases, 36 (7.6%) developed minor complications in which port removal was not needed; however, 15 ports (3.15%) had to be removed due to major complications. Seven ports (1.47%) were explanted due to treatment-resistant bacteremia and sepsis, in addition to 2 other ports (0.42%) because of port pocket infections. An additional 6 ports (1.26%) required explantation for the following reasons: skin necrosis (0.21%); incision dehiscence (0.21%); broken or torn catheter (0.42%); jugular vein thrombosis (0.21%); thrombosis of superior caval vein (0.21%). CONCLUSION: Radiological implantation of subcutaneous venous ports can be performed with similar or lower complication rates as compared to the surgical literature, due to the obvious advantage of imaging guidance. Hence, we think that port implantation with imaging guidance will become the preferred implantation method in the future.

Adolescent↗
PubMed2006

Evaluation of radiotherapy response of cervical carcinoma with gray scale and color Doppler ultrasonography: resistive index correlation with magnetic resonance findings.

PURPOSE: To investigate the role of the resistive index measured with transvaginal color Doppler ultrasonography (TVCDUS) for assessing the radiotherapy response of cervical carcinoma and to compare it with magnetic resonance findings. MATERIALS AND METHODS: A total of 13 patients with advanced stage cervical carcinoma (>IIA) underwent magnetic resonance imaging (MRI) and TVCDUS exams 6 months prior to and 6 months after radiotherapy. Pre- and post-treatment resistive indices obtained from the central and peripheral zones of the tumor were compared. These values were also compared with MRI findings and resistive indices obtained from the control group. RESULTS: Tumoral masses could be visualized in all patients with B-mode TVCDUS prior to the treatment. Resistive indices before and after treatment were 0.20-0.82 (mean: 0.52+/-0.15), and 0.70-0.99 (mean: 0.81+/-0.14), respectively. Eleven out of 13 patients responded to the treatment completely and no mass was detected in MRI and TVCDUS. Investigations were performed in areas with flow within the tumor-free cervix. A residual mass was noted in 2 patients with MRI and TVCDUS. There was a statistically significant difference between complete response to the treatment and increased resistive indices (P=0.001). In 2 patients with residual masses, no increase in resistive indices was detected. The mean resistive index of the control group was 0.65+/-13 and the difference was statistically significant compared to the resistive indices of the patients prior to the treatment. CONCLUSION: Since there was a significant correlation between the MRI findings and resistive indices, the spectral parameters obtained with TVCDUS were a good alternative to such an expensive modality as MRI in the evaluation of the response of cervical cancer to the treatment.

Adult↗
PubMed2005

Efficacy of transvaginal contrast-enhanced MRI in the early staging of cervical carcinoma.

The objective of this study was to evaluate the efficacy of transvaginal contrast for local staging of cervical carcinoma. Fifty patients diagnosed with cervical carcinoma prospectively underwent magnetic resonance (MR) imaging before and after vaginal opacification (VO) with a mixture of 25 ml saline and 25 ml barium. T2-weighted (T2W) TSE images in axial and sagittal planes were compared before and after vaginal opacification. Dynamic T1W images in sagittal and fat-suppressed T1W images in transverse planes were also evaluated after intravenous contrast administration. Involvement of vaginal wall, lumen, and fornices; parametrium; rectum; and bladder were noted. Changes in local tumor staging and in treatment planning were also assessed after vaginal opacification. MR results were later compared with surgical pathological findings. Twenty-eight patients who went through surgical staging were included in the study. VO did not change any of the MR interpretations in 14 patients (50%). Correct staging was achieved with T2W TSE images with and without VO (in sagittal and transverse planes) in 78.5% and 50% of the patients, respectively. VO correctly lowered staging in seven and increased it in three patients compared with sagittal standard T2W images. Treatment planning was also changed in four (14%) of these patients. When overall accuracy of MR staging to indicate the appropriate treatment was evaluated, patients would have received the proper treatment in 90% and 79% of the cases when only T2W sagittal images with and without VO were evaluated, respectively. Dynamic gradient-echo images in sagittal planes and postcontrast T1W images in transverse planes evaluated with T2W series after VO, accomplished correct staging in 23 (82%) of the patients. MRI staging in early cervical cancer may be difficult and overestimated, especially if the tumor is slightly extended into the proximal vagina. Use of vaginal contrast medium is an easy, well-tolerated, and effective method to better delineate the borders of the tumor. It increases the specificity and accuracy of MR staging by showing the exact relation of the tumor with the vaginal wall and beyond.

Adult↗
PubMed2005

Reproducibility of black-blood coronary vessel wall MR imaging.

PURPOSE: New magnetic resonance imaging (MRI) methods can provide high spatial resolution images of the coronary artery wall, and statistically significant differences in coronary vessel wall thickness between atherosclerotic disease patients and control subjects have been shown. The aim of this study is to assess inter-study reproducibility (i.e., repeatability) of the cross-sectional 2D coronary vessel wall MRI using a black-blood technique. METHODS AND RESULTS: Twelve healthy adult subjects were studied with the use of a commercial 1.5 T CMR system. A double inversion recovery fast spin-echo (FSE) sequence (black blood) was used. Each subject was scanned twice on different days. The mean RCA lumen area difference between study 1 and study 2 was 0.004 mm2, and the coefficient of repeatability (COR) was +/- 0.06 mm2. The mean RCA wall thickness difference between study 1 and study 2 was 0.02 mm, and the COR was +/-0.39 mm. CONCLUSION: Cross-sectional coronary vessel wall imaging with 2D double-IR FSE is highly reproducible for serial evaluation of coronary vessel walls and atherosclerotic coronary artery disease.

Adult↗
PubMed2004

[Unilateral open lip schizencephaly between central sulcus and third ventricle].

Imaging findings of schizencephaly as well as other neuronal migration anomalies have been well described. We present brain MR images of a 12-year-old boy who had open lip schizencephaly in which the transcerebral cleft extended between the third ventricle and the pial surface of the hemisphere. There were also other accompanying neuronal migration anomalies and corpus callosum agenesis.

Abnormalities, Multiple↗
PubMed2004

[Pneumosinus dilatans].

Pneumosinus dilatans is a localized abnormal dilatation of paranasal sinuses which contains only air and is covered with normal epithelium. We presented the X-ray, CT and MRI findings of three cases with pneumosinus dilatans secondary to arachnoid cyst and meningioma. When evaluating the patients with long-lasting symptoms, pneumosinus dilatans should be considered.

Adult↗