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Biomedical subjects

U A Shenoy

Publications and source records attributed to U A Shenoy.

8 recordsLinked to original sources
PubMed1987

Cytologic diagnosis and monitoring of Hodgkin's disease in cerebrospinal fluid: a case report.

Central nervous system (CNS) involvement in Hodgkin's disease is rare, but when the tumor extends into the CNS the route of tumor spread is similar to that seen in non-Hodgkin's lymphoma. Reed-Sternberg cells were identified in the cerebrospinal fluid (CSF) of a patient with Hodgkin's disease involving the CNS. Sequential cytologic examination of the CSF proved valuable in evaluating the efficacy of therapy. The ability to identify Reed-Sternberg cells in the CSF makes CSF cytology a useful adjunct in the management of patients with established or suspected CNS involvement of Hodgkin's disease.

Adult↗
PubMed1986

Prevalence of hematuria in urothelial neoplasia.

Voided urine specimens from 82 cases of histologically verified urothelial neoplasia (transitional cell carcinoma grades I, II, III, and carcinoma in situ [CIS] ) were evaluated for the presence of gross and microhematuria (MH). Microhematuria was assessed macroscopically with the reagent-strip blood test and evaluated microscopically with enumeration of erythrocytes using a standardized semiquantitative Papanicolaou-stained urine sediment examination. The authors' retrospective study indicated that gross hematuria rarely was present in urothelial neoplasia, however, occult blood (greater than 5 RBC/HPF) was present in four out of five cases when one sample was examined. In some cases there was an overlap between the number of erythrocytes excreted by control population and those with urothelial neoplasms. Urine sediment examination was more sensitive than reagent-strip testing for MH in patients with urothelial neoplasia.

Adult↗
PubMed1985

Reliability of urinary cytodiagnosis in urothelial neoplasms.

A retrospective study was done to explore the reliability of urinary cytologic examination of 117 cases of transitional cell carcinoma seen at this institution for the period 1980 to 1984. A specificity of 99%, sensitivity of 85%, false-positive rate of 11%, and false-negative rate of 10% were obtained. A single blind review of cytologic and histologic material from 66 of the cases was also performed for evaluation of the cytologic criteria employed for the grading of tumors. Cytohistologic correlation of grade I lesions was poor, whereas correlation of grades II and III was reasonably good. Carcinoma in situ was cytologically recognized in all instances but was difficult to distinguish from grade III carcinoma.

Carcinoma in Situ↗
PubMed1985

Current assessment of microhematuria and leukocyturia.

Technical advances in laboratory testing such as sensitive chemical tests and standardized commercial slides have significantly altered our entire approach to urinalysis. In addition, the recognition of the association of microhematuria with urologic neoplasms and the morphologically altered red blood cells with renal parenchymal bleeding is beginning to expand our knowledge of the pathogenesis of microhematuria. Future trends may include a broader range of chemical tests as well as a better understanding of disease processes associated with microhematuria.

Carboxylic Ester Hydrolases↗