Biomedical subjects

U Bernius

Publications and source records attributed to U Bernius.

3 recordsLinked to original sources

PubMed1986

Percutaneous litholapaxy.

The technique of puncture and dilatation 'in the hands of one' is described in detail based on almost 800 percutaneous operations on the kidney. All of the steps of the operation were carried out by the urologist himself. The advantages are presented and two new percutaneous instruments are introduced: a percutaneous working sheath and the lumbotome, a wire-guided, double-blade knife for cutting the percutaneous tract. The principle of percutaneous stone operation is explained as well as special complications which can occur. Finally, statistic results are discussed which clearly show a remarkable decrease of the residual and recurrent stone rate in comparison to conventional kidney stone surgery.

Adolescent↗

PubMed1980

[Efficency of tocoylsis by fenoterol and fenoterol in combination with a beta-1-blocking compound (author's transl)].

In 35 pregnant women threatening premature labour and cervic dilatation indicated therapy by a beta-mimetic compound (fenoterol) for tocolysis. 17 patients (group I) got fenoterol-monotherapy; in 18 patients (group II) fenoterol was combined with the cardioselective beta-1-blocking agent metoprolol. There were no differences in age, bodyweight and time of gestation in both groups before therapy; also the obstetric states--as compared by pelvic score (Bishop) and tocolysis index (Baumgarten)--were nearly identical. Efficiency of tocolytic therapy was evaluated by prolongation index (Richter) and tocolysis-success-score (Weidinger). Statistical analysis comparing these parameters in both groups showed no significant differences. Heartrate, however, was significantly (p > 0,005) lower in patients treated by fenoterol and metoprolol, thus indicating less cardial stress induced by fenoterol. In conclusion the combination of the semiselective beta-2-stimulating compound fenoterol with the beta-1-blocking agent metoprolol is proposed for tocolytic therapy because of less cardial stress but identical tocolytic efficiency as compared with fenoterol-monotherapy.

Drug Therapy, Combination↗

PubMed1980

[Clinical application of combined beta 2-stimulation and beta 1-blockade in tocolysis (author's transl)].

35 pregnant women were treated with the semiselective beta 2-stimulating compound fenoterol because of threatening premature labor. The efficiency of tocolysis and the cardiovascular effects of a mono-therapy with fenoterol were compared with a combined therapy with the beta 1-blocking compound metoprolol by the following parameters: Heart rate, systolic and diastolic blood pressure, left ventricular dimensions and mean Vcf as determined by echocardiography, pelvic score, tocolysis-index and tocolysis-success-score (Weidinger-score). Metoprolol caused a remarkable and highly significant reduction of the fenoterol-induced cardiac effects: increase of heart rate and augmentation of mean Vcf; the blood pressure was significantly lowered by metoprolol. The tocolytic effect of fenoterol in no respect was blunted by metoprolol.

Adrenergic beta-Agonists↗