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Biomedical subjects

U Bonelli

Publications and source records attributed to U Bonelli.

18 recordsLinked to original sources

[Acute thrombosis of the lower limbs: choice of treatment?].

The paper reports the Authors' experience of treating acute thrombotic-type ischemia of the lower limbs. It analyses the results obtained in 105 patients treated either using vascular reconstruction, loco-regional fibrinolytic therapy, or simple thrombectomy. Statistical analysis reveals a marked difference between reconstructive surgery and simple thrombectomy, whereas fibrinolysis was found to be a useful but limited method used only in patients with pallid ischemia and in circulatory compensation. In conclusion, the Authors sustain that an aggressive-type approach is currently the most reliable method to be used in all cases in which the patient's general and local conditions permit.

Acute Disease

[Aneurysms of the superficial femoral artery at the rupture stage. Apropos 2 personal cases].

The paper reports two case of aneurysms of the surface femoral artery during the rupturing stage. Preoperative clinical data are described together with intraoperative angiographic examinations. These led to the choice of different surgical techniques in the two patients, thus enabling their limbs to be saved. In addition, it is extremely important to carry out an echographic control of all areas which are most likely to be affected by aneurysmatic degeneration in subjects with both obstructive and dilatative arteriopathies in order to avoid emergency surgery.

Aged

[Traumatic lesion of the popliteal artery. Synthesis of our experience].

The Authors reported experiences from 26 traumas of popliteal artery; 2 are related to continuous microtrauma from exotosis; 2 vasospasms implied vascular intervention. Tibial artery bypasses with vein grafts have been advocated to obviate any exploration of popliteal hematoma. A multidisciplinary approach consisting of orthopedist, plastic and vascular surgeons should be employed.

Exostoses

[The current value of the whipstitch suture following carotid TEA].

There is no consensus of opinion regarding the type of suture to be used followed carotid TEA. The paper reports a study carried out in 123 operated patients who were followed for a variable period ranging from 6 months to 4 years with six-monthly controls using B-mode echotomography, supplemented by digital angiography via a venous route if necessary. A direct suture was used in 92 of the patients, while a venous patch was applied in the remaining 31. Subsequent controls revealed a relative frequency of restenosis of a fundamentally benign nature at a point which was proximal or distal to TEA. In addition, the study showed that continuous suture may be valid in male patients but doubts continue to exist regarding its use in female patients. In the latter, it is therefore preferable to encourage a more widespread use of the venous patch.

Adult

[Factors determining prognosis in the treatment of abdominal aortic aneurysm in the rupture stage].

Personal experience in the treatment of 70 ruptures of the subrenal abdominal aorta over the past 15 years is reported. The various factors determining prognosis are analysed with particular reference to the time between onset of symptoms and admission to hospital, clinical condition (state of shock, kidney function) and rupture location (anterior or posterior). Preoperative investigations and types of surgical treatment are described together with results. Despite the high mortality rate it is concluded that time and rupture location are the decisive factors in the prognosis for these patients, since all other factors are more easy to monitor and modify using modern techniques of intensive postoperative care.

Aorta, Abdominal

[Carotid lesion associated with contralateral occlusion: diagnostic and therapeutic approach].

The treatment of atheromatous carotid lesions combined with occlusion of the contralateral carotid artery remains a problem and one that is much debated. With this in mind the present paper reports personal experience of 25 cases, 16 treated surgically and 9 medically. The criteria for the selection of either type of treatment on the basis of the clinical situations, angiographic findings and Doppler ultrasound studies of the carotid plaque, are analysed. The surgical technique and the methods used in monitoring and protecting the brain during the operation are reported as are the short and long-term results. Finally, it is claimed that an "aggressive" approach is appropriate in such cases, thought there are situations in which careful monitoring of the lesion may be the first logical reaction to the treatment of these patients.

Aged

[Fibrinolytic treatment in acute ischemia caused by thrombosed popliteal aneurysm. Apropos of 2 cases].

Two personally observed cases of ischaemia of the lower extremities due to thrombosis caused by a popliteal aneurysm are presented. While surgery is known to be treatment of choice, in these cases locoregional fibrinolysis was preferred. It seems useful to detail the advantages of this approach that has never appeared in the literature as a treatment for aneurysmatic pathologies.

Acute Disease

[Effects of fibrinolytic therapy in acute ischemia of the lower limbs].

In this paper the Authors illustrate their experience of loco-regional fibrinolytic medical treatment in patients suffering from acute thrombotic-type ischemia of the lower limbs. The clinical, ultrasonographic and angiographic criteria leading to the choice of this form of treatment rather than surgery are examined. The Authors outline the reasons which led them to give preference to the use of plasminogen tissue activators (rt-PA) rather than other fibrinolytic agents; the results obtained are evaluated not only in terms of immediate permeability but also in relation to the additional procedures required to ensure a correct therapeutic iter. In conclusion, the paper underlines the need to assess the indications for this type of therapy with great care since "washing" the distal vascular bed may be decisive for successful treatment even in the event of possible future surgery.

Acute Disease