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Biomedical subjects

U C Lahori

Publications and source records attributed to U C Lahori.

At least 19 recordsLinked to original sources
PubMed1981

Hepatoblastoma.

Explore the source record for details and available documents.

Carcinoma, Hepatocellular↗
PubMed1979

Hepatitis A and Indian childhood cirrhosis.

Antibody to hepatitis A virus (anti-HAV) was found in 50% of patients with Indian childhood cirrhosis; this was not significantly different from the prevalence of anti-HAV in age- and sex-matched controls.

Antibodies, Viral↗
PubMed1979

Inheritance of Indian childhood cirrhosis.

Detailed pedigree charts were prepared from 120 index patients suffering from Indian childhood cirrhosis (ICC). Of the 120 families, 84 were informative for segregation analysis. Since families were ascertained through patients who came to hospital for treatment, the data were analyzed according to a single-selection model. The observed segregation ratio for the entire data was significantly lower than the one expected under the hypothesis of autosomal recessive inheritance (p = smaller than 0.005). On the other hand, the segregation data for families with at least two affected children (multiplex families) were compatible with autosomal recessive inheritance. On this basis, however, at least 50% of all the cases of ICC would have to be of nongenetic origin. Alternatively, analysis of the data by the Falconer method indicated that ICC could be of multifactorial origin with very strong genetic determination (over 85%).

Age Factors↗