Washing feather and synthetic pillows.
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Allergens↗
Biomedical subjects
U Deppe
Publications and source records attributed to U Deppe.
The effects of ABR stimulus repetition rate in multiple sclerosis.
The purpose of this study was to monitor the effects of auditory brain stem response (ABR) repetition rate in previously confirmed multiple sclerosis (MS) patients. Ten definite MS patients (20 ears) presenting neurological evidence of brain stem involvement were tested. All patients had hearing thresholds of 20 dB HL or better between 250 and 4000 Hz. ABRs were recorded with four click stimulus repetition rates at 70 dB SL. An analysis of variance (ANOVA: Group X Rate X Ear) resulted in significant group (normal versus MS) and rate (10, 33, 67, and 80/sec) effects. Increasing the repetition rate significantly improved the detection of abnormal latency measures (Duncan's multiple range test). Absent or prolonged wave I response latencies were recorded in 25 to 40% of all MS patients tested and were rate dependent. The findings of this study encourage the inclusion of faster repetition rates when using ABR as a supportive measure in the diagnosis of suspected MS patients.
Acoustic Stimulation↗
The cellular anatomy of embryos of the nematode Caenorhabditis elegans. Analysis and reconstruction of serial section electron micrographs.
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Animals↗
Cell lineages of the embryo of the nematode Caenorhabditis elegans.
Embryogenesis of the free-living soil nematode Caenorhabditis elegans produces a juvenile having about 550 cells at hatching. We have determined the lineages of 182 cells by tracing the divisions of individual cells in living embryos. An invariant pattern of cleavage divisions of the egg generates a set of stem cells. These stem cells are the founders of six stem cell lineages. Each lineage has its own clock--i.e., an autonomous rhythm of synchronous cell divisions. The rhythms are maintained in spite of extensive cellular rearrangement. The rate and the orientation of the cell divisions of the cell lineages are essentially invariant among individuals. Thus, the destiny of cells seems to depend primarily on their lineage history. The anterior position of the site of origin of the stem cells in the egg relates to the rate of the cell cycle clock, suggesting intracellular preprogramming of the uncleaved egg. We used a technique that allows normal embryogenesis, from the fertilized egg to hatching, outside the parent under a cover glass. Embryogenesis was followed microscopically with Nomarski interference optics and high-resolution video recording.
Animals↗
Dichotic paradigms in multiple sclerosis.
A total of 20 "definite" multiple sclerosis patients were administered three commonly used dichotic speech paradigms. The tests included the Consonant-Vowel (CV) Nonsense Syllable test, the Synthetic Sentence Identification (SSI) test, and the Staggered Spondaic Word (SSW) test. Results of the test procedures were variable, with the higher percentage of abnormalities obtained with the CV test, followed by the SSI, and finally, the SSW. These findings suggest that brain stem lesions may influence higher order auditory processing as measured by certain dichotic test procedures.
Adult↗