Biomedical subjects

U Dillmann

Publications and source records attributed to U Dillmann.

22 records · Page 2Linked to original sources

PubMed1988

Somatosensory evoked potentials aiding the diagnosis of brain death.

SEP were recorded in 14 patients, who fulfilled the clinical and electroencephalographic criteria of brain death. The results are compared with the respective ones in healthy subjects. Beside the absence of cortical N 20 in each brain dead patient, reduction of amplitude or absence of near field negativity (N 13b) from upper neck regardless of the position of the reference electrode represents the predominant result. The near field potential from the lower neck (N 13a) was unaffected. The counterpart in the far field potential recorded from F z was amplitude reduction of P 13. These results suggest that the dissociation of N 13a and N 13b can confirm the diagnosis of brain death. Moreover these results support the view of two independent generators of N 13a and N 13b despite their identical amplitude and latency.

Brain Death↗

PubMed1988

[The repetitive muscular action potential in neuromuscular transmission disorders due to acetylcholinesterase inhibition].

Neuromuscular transmission was studied in 11 patients with organophosphate intoxication. The compound muscle action potential (MAP) was recorded from the thumb after single, repetitive (1-50 Hz) and paired stimulation. All patients showed a prolonged MAP. The duration increased with the severity of intoxication. The number of peaks varied only slightly. In all cases repetitive stimulation reduced the later components of the MAP. There was no correlation with tetanic fade of the initial negative component. One patient had a pronounced tetanic fade but a slight reduction of repetitive components. In view of experimental studies a combined pre- and postsynaptic effect seems to be responsible.

Action Potentials↗

PubMed1988

[The effect of a reference electrode on the configuration of somatosensory evoked potentials].

Early somatosensory evoked potentials to median nerve stimulation were recorded in 6 normal adults from the scalp and the neck. Simultaneous derivations consisted of a recording with a cephalic reference, recordings of both electrodes with a noncephalic reference and an arithmetically subtraction of these potentials. The electrodes were placed over the scalp (P4'), the lower and the upper neck and the reference electrodes over the midfrontal region (Fz), both ears (M1/2) and the contralateral hand. P15/P16 in the P4'-Fz derivation had no identity to the far field potentials (FFP) P13/P14 recorded from the scalp with hand reference. FFP P9 and P11 from the ear lobes was abolished in the P4'-M1/2 derivation and the residual positive waves corresponded to P13 and P14. None of the electrodes picked up a wave equivalent to P15 regardless of the reference electrode. In the neck (CV 7) - scalp derivation NSEP9, 13 and 14 corresponded to the FFP P9, 13 and 14. NSEP11 differed in latency from P11 and N11. There was no latency shift from the lower (CV 7) to the upper (CV 2) neck. NSEP9 and 11 was enhanced in amplitude from CV 7, which resulted from different polarities (N11/P11) over CV 7 and CV 2. These results indicate the necessarity of potential analysis with respect to the activity of the recording electrodes.

Adult↗

PubMed1985

Correlation of the chemiluminescence-activity of peripheral blood monocytes with CSF parameters of inflammation and the clinical course of patients with lymphocytic meningoencephalitis.

The chemiluminescence-activity (CL-A) of peripheral blood monocytes (MO) was measured in eight patients with lymphocytic meningitis or meningoencephalitis and compared to CSF parameters and the clinical course. The initial maximum CL-A was around four times above the control and decreased to normal values within approximately 20 days. Poor correlations were found when the CL-A was compared to CSF parameters in the total group of patients. With regard to the CSF parameters in individual patients the CL-A was closely related to the cell count, to a lesser degree to the protein content, but not to the IgG content. Finally, a very good correlation of the CL-A was found with the clinical course in individual patients. This preliminary data suggests the clinical usefulness of CL-measurements and supports the conception that the CL-A predominantly reflects the specific cellular phase of inflammation, which is dominated by T cells.

Adolescent↗