[Bone pain in the last pregnancy trimester].
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Biomedical subjects
Publications and source records attributed to U Dziambor.
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We report on a 31-year-old II gravida I para treated because of a hydatidiform mole, hyperthyroidism and acute renal failure in the 16th week of pregnancy. The pathomechanism of trophoblast-induced hyperthyroidism will be discussed. To our knowledge this is the first report on acute renal failure in association with trophoblast-induced hyperthyroidism.
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The significance of intra-arterial cytostatic drug infusion in connection with histologically confirmed recurrences of squamous carcinomas was investigated within a clinical controlled trial between 1978 and 1985. Patients selection according to strict precaution in consideration of the factors influencing prognosis. After clinical examination, computer-tomographic, sono- and angiographic staging ten patients received MTX and 5FU i.a., completed by intra-venous CMFV-treatment in cases with objective remission of disease (therapy arm A). Six women received FACV-combination only systemically (therapy arm B). One partial (PR) and fife moderate remissions (MR) were achieved by intra-arterial chemotherapy in early time. The median duration of survival was 7.5 month for patients in therapy arm A. Significant prolongation of cumulative survival time (p less than 0.05) was determined only by remission of disease in patients with grade performance status 0-1 WHO. Intra-arterial chemotherapy showed lower toxicity versus systemic FACV- or CMFV-treatment. No complications of using prolonged i.a. infusion by Seldinger's technique were encountered. Further studies for within interdisciplinary scientific research in more chemosensitive malignancies of the female genital tract are warranted.