Biomedical subjects

U Engzell

Publications and source records attributed to U Engzell.

16 recordsLinked to original sources

PubMed1990

Efficacy of fine-needle aspiration and sampling of lymph nodes in 1,484 Chinese patients.

A retrospective study of 1,855 fine-needle aspirations of the lymph node (LN) from 1,484 Chinese patients in Queen Mary Hospital over a period of 11.5 yr (January 1, 1976, to June 30, 1987) was reviewed and analyzed. Positive cytologic results diagnosed malignancies in 49.3%. Sensitivity and specificity of cytology reached 95% and 96.5%, respectively. The order of frequency of the metastatic tumors according to primary sites was analyzed. The most common metastatic carcinomas in various groups of LNs were nasopharyngeal carcinoma in the cervical LN, breast carcinoma in the axillary LN, and cervical carcinoma in both the groin and pelvic LNs. Tuberculosis (TB) is an important differential diagnosis; FNAC showed a sensitivity of 76.9% in the detection of TB lymphadenopathy.

Adolescent↗

PubMed1983

Nasal and sinonasal cancer. Connection with occupational exposures in Denmark, Finland and Sweden.

A joint Danish-Finnish-Swedish case-referent investigation was initiated in 1977 in order to study the connection between nasal and sinonasal cancer and various occupational exposures. All new cases of nasal and sinonasal cancer were collected from the national cancer registers (Finland and Sweden) or from the hospitals (Denmark). Those still alive who agreed to an interview (N = 167) were individually matched for age and sex with patients with colonic or rectal cancer. A detailed telephone interview was made according to standardized forms. Both cases and referents thought that their condition was the one under study. The exposures were coded blindly by an industrial hygienist. The results showed associations between nasal and sinonasal cancer and exposure to (i) hardwood or mixed wood dust (discordant pairs 14: 2), (ii) softwood dust alone (13:4), (iii) chromium (16: 6), (iv) nickel (12: 5, not significant), (v) welding, flame-cutting and soldering (17: 6), and (vi) lacquers and paints (14: 0). The last finding was probably due to confounding from wood dust exposure. Hardwood dust exposure was associated with adenocarcinoma. Softwood dust exposure alone was associated with epidermoid and anaplastic carcinomas. No associations were found for a number of exposures, including agricultural chemicals, textile dust, asbestos, quartz dust, organic solvents and leather work. Possible exposure to formaldehyde was evenly distributed between the cases and referents.

Adenocarcinoma↗

PubMed1983

Nasal cancer and occupational exposures. Preliminary report of a joint Nordic case-referent study.

Nasal and sinus paranasal cancers have been associated with several occupational exposures, for example, dust from hardwood, nickel and unspecific agents occurring in the boot and shoe industry. A joint Danish-Finnish-Swedish case-referent investigation was initiated in 1977 to study further the connection between nasal and sinus paranasal cancers and various occupational exposures. All new cases of these cancers were collected from the national cancer registers (Finland & Sweden) or from hospitals (Denmark). Those still alive who agreed to the interview (N = 167) were individually matched for age and sex with patients with colonic or rectal cancer. A detailed telephone interview was performed according to a standardized procedure. Both the cases and referents thought that their condition was the one under study. The exposures were coded blindly by an experienced industrial hygienist. The results showed associations between nasal or sinus paranasal cancer and exposure to hardwood or mixed wood dust (discordant pairs 14/2); softwood dust alone (13/4); chromium 16/6); nickel (12/5, not significant); welding, flamecutting, and soldering (17/16); and lacquers and paints (12/0). Hardwood dust exposure showed a connection with adenocarcinoma. Softwood dust exposure alone was associated with epidermoid and anaplastic carcinomas. No associations were found for a number of exposures, including agricultural chemicals, textile dust, asbestos, quartz dust, organic solvents, and leather work. Possible exposure to formaldehyde was evenly distributed between the cases and referents.

Adult↗

PubMed1979

Occupational etiology and nasal cancer. An internordic project.

Reports from Britain and other countries have shown an increased frequency of adenocarcinoma of the nose and paranasal sinuses among workers exposed to fine wood dust. With support from the Nordic Council a joint project has been launched in Denmark, Finland, Norway and Sweden to single out occupations and exposures possibly associated with nasal cancer. The project is a prospective case-referent study with matched control cases of colon cnacer. Each new case of malignant eipthelial tumour of the nose and sinuses reported to the individual national cancer registries is interviewed concerning previous occupational exposures according to the program. The estimated duration of data collection is two years. This type of joint study is new to the Nordic countries and we hope to gain valuable experience in order to improve cooperation within this type of medical research. A retrospective study in Sweden has shown that 50% of all male cases of nasal adenocarcinoma from 1960 to 1972 were joiners, most of them cabinet makers. The duration of exposure to fine wood dust was known in 21 of 22 cases. The latency period varied from 22 to 70 years, with a mean value of 44.7 years. The exposure period varied from 9 to more than 30 years. The results correspond to those reported from Britain and Denmark.

Adenocarcinoma↗

PubMed1971