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U Grupp

Publications and source records attributed to U Grupp.

5 recordsLinked to original sources
PubMed1979

[Analytical characterization of palatinit (author's transl)].

The reaction product of the catalytic hydrogenation of isomaltulose (palatinose) is a mixture of alpha-D-glucopyranosido-1,6-sorbitol and alpha-D-glucopyranosido-1,6-mannitol designated palatinit. Because of its high potential as a sugar substitute methods for the identification and characterization of hydrogenation products and for the determination of palatinit as an ingredient in food preparations and biological samples are required. Several working procedures are described in full detail including thin layer and gas chromatography as well as enzymatic and chemical determinations.

Chromatography, Gas↗
PubMed1978

Metabolism of hydrogenated palatinose, an equimolar mixture of alpha-D-glucopyranosido-1,6-sorbitol and alpha-D-glucopyranosido-1,6-mannitol.

Hydrogenated palatinose, an equimolar mixture of alpha-D-glucopyranosido-1,6-sorbitol and alpha-D-glucopyranosido-1,6-mannitol, was investigated as a potential oral sugar substitute in the following experiments in man and rat. 1. Enzymatic cleavage occurred at slow rates by maltase (alpha-glucosidase) of jejunal mucosa, liver lysosomes and yeast. 2. Part of ingested hydrogenated palatinose arrived unsplit at the caecum of the rat and underwent fermentation there; excretion in feces and urine are neglegible in man and rat. 3. Growth and maintenance of rats demonstrated 20--40 percent diminished caloric utilisation of diets containing 34.5 percent hydrogenated palatinose whereas indirect calorimetry in man showed about 50 percent caloric deficit. 4. Blood sugar did not increase in man after oral doses up to 100 g. 5. The capacity of the rat kidneys for excretion of hydrogenated palatinose and its constituents was high, symptoms of incompatibility were not observed.

Blood Glucose↗
PubMed1977

[Metabolic behavior of disaccharide alcohols and related substances].

The present study suggests that part of the digestion of disaccharide alcohols is due to microbic processes, primarily in the cecum. The utilization of sorbitol and palatinitol by endogenous metabolic systems seems to be restricted insofar as these substances become accessible to the intestinal flora. Interim products of the bacterial fermentation are likely to be utilized by the host organism.

Disaccharides↗