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Biomedical subjects

U Hertel

Publications and source records attributed to U Hertel.

5 recordsLinked to original sources

Immunoadsorption--a new therapeutic possibility for multiple sclerosis?

A 46 year old woman suffers from chronic progressive multiple sclerosis. She was diagnosed in 1993. Because of many complications seen in conservative treatment, plasma exchange was started. The expanded disability status scale by Kurtzke could be improved but the interval between the treatments became shorter and shorter. It was therefore decided to commence protein A immunoadsorption treatment. With this treatment the patient shows good and stable improvement in neurological and functional status with an acceptable treatment frequency of once every 3 weeks.

Chronic Disease↗

[Studies on the kinetics of sulfaclomide and the effect of sulfaclomide therapy on p-aminohippuric acid clearance in pregnancy].

After a single oral dose and after 11 day repeated administration of Sulfaclomide elimination half-life of Sulfaclomid was not different in pregnant and in nonpregnant women. The initial serum concentrations of Sulfaclomid are lower in pregnant than in nonpregnant persons. Nearly all Sulfaclomid measurable in serum exists from unchanged sulfonamide. This rate does not change during treatment. By treatment with Sulfaclomid elimination half-life of p-aminohippurate (PAH) is shortened, renal excretion of p-aminohippurate is significant increased.

Aminohippuric Acids↗