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Biomedical subjects

U I Balldin

Publications and source records attributed to U I Balldin.

44 records · Page 3Linked to original sources
PubMed1976

The effects of body position and a vasodilator on xenon133 elimination from human subcutaneous fat.

The elimination of Xe133 from a deposit in the subcutaneous adipose tissue adjacent to the anterior tibial muscle was recorded by an external scintillation detector in 16 human subjects in sitting and in supine body position in a neutral environmental temperature (28 degrees C). The xenon clearance rate was increased in supine compared to sitting body position by a mean of 33%. I also studied the effect of a sympathomimetic beta 2-receptor stimulating agent using the same technique in 16 supine subjects. A perorally administered ester of terbutaline increased the xenon-elimination rate by a mean of 103%. The increased xenon-elimination rates in the supine body position and after the drug administration may reflect corresponding increases in adipose-tissue blood flow. The findings are in accordance with earlier measurements of an increase in central and peripheral blood flow and an increased whole-body, nitrogen-elimination rate during supine body position. The results might be of importance in decompression routines and in the treatment of decompression sickness.

Adipose Tissue↗
PubMed1976

Intracardial bubbles during decompression to altitude in relation to decompression sickness in man.

Doppler ultrasound was used in five subjects to detect intracardial gas bubbles during decompressions to altitude. At a simulated altitude of 8,000 m, neither intracardial bubbles nor symptoms of decompression sickness occurred. At 9,000 m, bubbles were registered in two subjects, one of which had questionable bends. At 11,500 m, bubbles were registered in all but one subject and two had bends. The three subjects who had not gotten bends were exposed to an air-breathing period of 30 min or, in one case, even 45 min at 2 ATA, for extra nitrogen loading, followed by decompression to 11,500 m. These subjects had heavy showers of bubbles followed by bends. In all cases with decompression sickness during the decompressions to altitude, intracardial bubbles were registered prior to the appearance of symptoms. The technique may be used in studies of decompression sickness without provoking actual symptoms, thus making the studies safer.

Brain Diseases↗
PubMed1976

Xe133 elimination from human fat during negative- and positive-pressure breathing.

The elimination of Xe133 from a deposit in the subcutaneous adipose tissue outside the anterior tibial muscle was recorded by an external scintillation detector in 16 human subjects during normal breathing, negative-pressure breathing (-20 cm H2o), and positive-pressure breathing (+20 cm H2O). The ambient temperature was kept at 28.0 degrees C +/- 0.1 degrees, which can be considered a neutral temperature. The xenon clearance rate was increased during negative-pressure breathing by a mean of 68% and decreased during positive-pressure breathing by a mean of 73% when compared to normal breathing. The xenon-elimination rates during the different conditions may reflect corresponding changes in adipose-tissue blood flow. Because both negative- and positive-pressure breathing may occur during diving, the uptake and elimination of inert gases in adipose tissue of a diver may be influenced; thus, the risk of decompression sickness might also be affected. The results may therefore be of importance in diving routines and in the construction of breathing apparatus for divers.

Adipose Tissue↗