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Biomedical subjects

U Kappeler

Publications and source records attributed to U Kappeler.

4 recordsLinked to original sources
PubMed2003

[Effects of hip arthroplasty followed by by inpatient rehabilitation on physical function and quality of life].

The aim of the present study was to investigate the effects of hip arthroplasty followed by an inpatient rehabilitation. Moreover, the relationships among functional status, quality of life and satisfaction with life or health status were examined. Patients were assessed before hip arthroplasty, at the start and at the end of the inpatient rehabilitation. Functional status was measured by using the WOMAC questionnaire and quality of life with the Medical Outcome Survey Short Form 36 (SF-36). Satisfaction was determined with a specific questionnaire (FLZ). Hip arthroplasty followed by an inpatient rehabilitation resulted in significant and clinically highly important improvements of functional status, quality of life and satisfaction with health and life.

Adult↗
PubMed1996

[Prévot nailing, an elegant method. Experiences with 38 personal cases].

Endomedullar elastic stabilization with titanium Prévot nails is an excellent method of treating long-bone fractures in children. Without touching the epiphyseal line, this method guarantees early functional follow-up treatment with minimal operative trauma. For this reason, this method can compete successfully with common methods like extension treatment, external fixation and osteosynthesis with plates. From October 1990 to October 1993 we treated more than 40 fractures with Prévot nails and checked 38 of them clinically and radiologically. All 17 femur fractures healed correctly from an anatomical point of view and without rotation defects. In 4 patients we found a maximum difference in length of 1 cm in favor of the operated side. All of the 11 forearm fracture had good results, but there were 2 poor results with delayed union (adult patients) in the 6 humerus fractures operated upon. The remaining 4 cases, had to do with exceptional indications like lower leg fractures, combined humerus and forearm diaphyseal fractures, and metacarpal diaphyseal fractures. Our first experience with this method is good. The duration of hospitalization is short and early functional follow-up treatment for pediatric diaphyseal fractures is in general practicable. This procedure for operative care of femur and forearm diaphyseal fractures has now become the standard therapy in our clinic.

Bone Nails↗
PubMed1982

Transient reversal of thrombocytopenia in idiopathic thrombocytopenic purpura by high-dose intravenous gamma globulin.

Since recent observations indicate that treatment with high-dose intravenous polyvalent intact immunoglobulin leads to a rapid reversal of thrombocytopenia in the idiopathic thrombocytopenic purpura (ITP) of childhood, we decided to apply this treatment to adults with ITP and to test the possibility that the effect of the immunoglobulin might be attributable to transient blockade of the reticuloendothelial system. Using sequential clearance studies of autologous 99mTc-labeled and anti-Rh(D)-sensitized erythrocytes in four adults with ITP who were treated with total doses of 1 to 1.5 g of immunoglobulin per kilogram of body weight, we found that a transient rise in platelet counts to normal levels within four to five days was accompanied by a marked temporary prolongation of the immune-particle clearance time. These data suggest that commercial intravenous immunoglobulin preparations may interfere with phagocyte Fc-receptor-mediated immune clearance. Since platelets in ITP treated with immunoglobulin were fully hemostatic, this type of therapy may allow surgical procedures to be performed safely in patients with this disease.

Adolescent↗