Biomedical subjects

U Kocer

Publications and source records attributed to U Kocer.

4 recordsLinked to original sources

PubMed2004

Total anonychia congenita: a rare heterogeneic disorder.

Total anonychia congenita is a very rare disorder in which all the finger nails and the toenails are absent without significant bone anomalies. This condition is reported to have an autosomal dominant inheritance pattern. There are a variety of syndromes or conditions associated with anonychia congenita. In this study we present a monozygotic twin with isolated anonychia congenita totals. Interestingly there is no family history of anonychia and this condition seems to be caused by a sporadic mutation.

Bone Diseases↗

PubMed2003

Sporadic familial polydactyly.

Polydactyly is one of the most common congenital deformities of the hands. It can occur as an Isolated disorder, in association with other malformations of the hands or feet, or as part of a syndrome. It can occur sporadically but it can also be inherited with a mainly autosomal dominant inheritance. We present a family with three out of four members of the last generation with no previous history of polydactyly. Although the affected children presented different phenotypes of polydactyly, probably all three cases were the result of the same mutation seen in one of the parents. In addition no syndromic association could be found. Our experience with the management of this family's members is presented and possible etiological factors and treatment modalities are discussed.

Child↗

PubMed1995

Tissue expansion-assisted prefabrication of the forehead flap for nasal reconstruction.

A new technique for nasal reconstruction is described. This method--expansion-assisted flap prefabrication--is essentially a simultaneous application of pretransfer grafting and tissue-expansion procedures for creating custom-made forehead flaps to meet varying requirements of nasal reconstruction. We have applied this new technique on seven patients, with full-thickness nasal defects during a 3-year period. Results from these patients are presented with a review of different use of flap prefabrication principles in nasal reconstruction.

Adolescent↗

PubMedDate not supplied

Effect of aesthetic rhinoplasty on respiratory functions.

Joseph's rhinoplasty operation, with minor modifications, was performed on 20 patients for aesthetic reasons. Various tests of the patient breathing though the nose were carried out both in the preoperative period and 10, 30, and 90 days after surgery. Respiratory-function test results improved in the majority of patients after rhinoplasty. FVC increased in 65% of the cases at day 10, in 85% at day 30, and in 75% at day 90. FEV1 increased in 65% of the cases at day 10, in 65% at day 30, and in 70% at day 90. FEV1/FVC increased in 60% of the cases at day 10, in 65% at day 30, and in 70% at day 90. The only statistically significant increase when compared with preoperative values was the increase in the values of FEV1/FVC at the 30th postoperative day. Decreases in respiratory function test values were insignificant in most of the patients. FEV1/FVC x 100 decreases of more than 10% were seen in three patients, indicating increased nasal resistance, at the 90th postoperative day. However, the lowest value was 50.4 and none of the patients reported subjective nasal obstruction. In conclusion it was observed in this study that properly executed cosmetic rhinoplasty did not have any significant negative effects on respiratory functions in most patients, and improved respiratory functions in most.

Adult↗