Congenitally isolated cavernous bodies.
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Adult↗
Biomedical subjects
U Kuyumcuoğlu
Publications and source records attributed to U Kuyumcuoğlu.
Cavernous oxygen tension in the patients with erectile dysfunction.
We designed a study consisting of 27 consecutive patients with erectile dysfunction in order to evaluate the role of cavernous oxygen tension. Patients were completely evaluated by history, physical examination, multiple blood analyses, serum testosterone level measurements, papaverine test, color duplex sonography and dynamic infusion cavernosometry-cavernosography. Blood gas samples were obtained from femoral artery and corpus cavernosum before drug injection and also from corpus cavernosum at 5, 10, 20, 30, 40 min following drug injection. Aetiologic classification of erectile dysfunction in our patients was as follows: psychogenic in 8, cavernosal failure in 14 and arterial disease in 5 cases. At flaccidity, no significant differences were found in the mean pO2, sO2, pCO2 and pH values of patient groups. After injection of intracavernous papaverine, results of the cavernous pO2 (P < 0.05), sO2 (P < 0.05) levels were found to be statistically significantly different between patients with vascular and psychogenic erectile dysfunction. Analysis of maximal cavernosal oxygen tension and PSV revealed statistically significant correlation (r = 0.66, P < 0.001). The results of this study suggest that changes in arterial and cavernosal pO2 and sO2 values may be contributing factors or co-factors in erectile failure.
Adult↗
An enigma: contralateral effects of experimental unilateral testicular torsion.
To investigate the effects of unilateral testicular torsion on both testes, we studied 4 groups of adult male New Zealand rabbits using sham operation, torsion and detorsion after one or eight hours and permanent torsion. Bilateral orchiectomy was performed 9 weeks after the operation, and testicular weights, Johnsen scores, quantitative analyses, tubular diameters were calculated and histopathologic diagnosis was determined. Testicular weights, Johnsen scores, spermatid counts and tubular diameters were all decreased in torsioned testes depending on the duration of torsion. The contralateral testes showed no significant change in any of the study groups when compared with the control group.
Animals↗
Effect of intracavernosal sodium nitroprusside in impotence.
Recent studies have shown an important role for nitric oxide (NO) in cavernous smooth muscle relaxation. In this study the intracavernosal effects of the NO donor sodium nitroprusside (SNP) were investigated in 32 patients with erectile dysfunction. Erectile response and penile blood flow were investigated following intracavernosal administration of 360 micrograms SNP and 60 mg papaverine for diagnostic purposes. In all of 32 patients the erectile response to SNP was not better than that to papaverine. Haemodynamic evaluation of the deep penile arteries was carried out by colour duplex Doppler sonography after administration of SNP and papaverine. No differences in peak flow velocities were measured, but the increases in diameter and end-diastolic velocities were higher after SNP than after papaverine. Our data suggest that the NO donor SNP is not a new alternative agent for diagnosis and treatment of impotence.
Adult↗
Perineal ultrasonography in postoperative assessment of two different surgical procedures for stress urinary incontinence.
Thirty-eight incontinent and 57 continent patients who had undergone MMK urethropexy and anterior colporrhaphy procedures were examined by perineal ultrasonography. Bladder neck hypermobility was described with ventrodorsal and cephalocaudal directional parameters. In the incontinent patients both cephalocaudal and ventrodorsal mobilities were found to be significantly greater compared to the continent group, the latter ultrasonographic parameter being relatively more significant (P < 0.01 and P < 0.001, respectively). In surgically cured patients who underwent the MMK procedure both ventrodorsal and cephalocaudal mobility had been significantly limited in contrast to their incontinent counterparts; but these differences had been detected only in ventrodorsal mobility by the anterior colporrhaphy procedure.
Female↗
Oxytocin-induced contractions of the rabbit corpus cavernosum.
The contractile effect of oxytocin on isolated rabbit corpus cavernosum strips was investigated. Concentration-response curves to oxytocin and phenylephrine were obtained. Oxytocin repetitively induced concentration-dependent contractions in the corpus cavernosum strips. The maximal contractile response to oxytocin was in amplitude 39.4 +/- 9.1% of that to phenylephrine. The slopes of the concentration-response curves, the amplitude of the maximal contractile effects, and the pD2 values of oxytocin obtained in endothelium-denuded strips were not significantly different from those of intact preparations. The results of this study demonstrated that oxytocin contracts the rabbit corpus cavernosum, but the endothelium does not contribute to this effect. Since oxytocin is less efficacious than phenylephrine, it seems unlikely that this hormone can serve as an alternative in the treatment of prolonged penile erections.
Animals↗
Hydatid cyst of the seminal vesicle.
Hydatid disease has a high incidence in our country and causes significant complications. The authors present a case of unusual localization of hydatidosis, hydatid cyst of the seminal vesicle, and a review of the literature.
Adult↗