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Biomedical subjects

U Lips

Publications and source records attributed to U Lips.

31 records · Page 2Linked to original sources

[Triflupromazine-effects in electroencephalogram (author's transl)].

Changes of EEG and Computer-EEG have been studied in a group of young patients premedicated intravenously with 10 mg of Triflupromazine, Druginduced changes of cerebral function caused especially variations of alpha-amplitude, in addition an increase of delta-delta/theta- and occasionally of beta-activity. The extend of EEG-changes depended on the individual weight-orientated dosage of Triflupromazine EEG-results and clinical data of quieting and sedative effects showed-with one exception-good correlation.

Adult↗

[Respiratory training with intermittent positive pressure in acute respiratory disturbances (author's transl)].

In a clinical study the applicability and effectiveness of breathing therapy with intermittent positive pressure in cases of incipient or already established pulmonary complications are evaluated. The case material was divided into four groups: 1. Imminent respiratory complications (haemorrhagic shock, flail chest); 2. acute postoperative pulmonary insufficiency in old patients; 3. postoperative alveolar or interstitial pulmonary oedema; 4. postoperative pneumonia. Individual respiratory training succeeded in all patients in significantly improving the arterial blood gases; prolonged artificial ventilation could be dispensed with. The method and its limitations and indications for its use are reviewed.

Abdomen↗

[Pheochromocytoma in pregnancy--pathophysiology and therapy (author's transl)].

In this paper pathophysiology of pheochromocytoma and its modern diagnostic and therapeutic management are discussed with special regard to the combination of pheochromocytoma and pregnancy. The preoperative treatment with phenoxybenzamine is evaluated. As for the anesthetic management barbiturates and neurolept anesthesia are recommended. In the acute treatment of extreme blood pressure values sodium nitroprusside is preferred to phentolamine. Whereas vaginal delivery is contraindicated in a patient with pheochromocytoma there is no definite superiority of tumorresection along with caesarean section against a separate abdominal procedure.

Adrenal Gland Neoplasms↗

[Eeg-effects of promethazine. study on 17 patients (author's transl)].

Changes in EEG and cEEG were studied in two groups of patients premedicated with promethazine in a dosage of 50 mg iv; study group A consisted of patients whose age ranged from 20-50 years and study group B of patients whose age was above 70 years. The observation time was 15 min but in a few patients only it was extended to 60 min. Changes in behaviour were clinically controlled. Blood pressure and pulse-rate measurements were taken at regular intervals. The first taken base line electroencephalogram patterns of the patients in group A were unremarkable. The recordings of the patients in group B showed a high percentage of deviation from normal. The sedative effect of promethazine showed a widespread individual variation as did also the characteristic changes in EEG frequency bands. Psychomotor side-effects were frequently seen. Characteristic changes in EEG were found to be a continuing 20%-50% decline of alpha amplitude mostly combined with an alternation of stability, or a narrowing of the frequency range in the higher beta band. In addition a light increase of delta and theta activity was observed. Blood pressure and pulse-rate showed a light increase.

Adult↗

[EEG effects of diazepam. Studies on 16 patients (author's transl)].

Recordings of the electrical activity of the brain were obtained by using conventional EEG and computerized EEG. Both methods of recording have been used as an indicator of the cerebral condition before and after intravenous premedication with Diazepam 20 mg. Two groups of patients were studied. The first group consisted of younger patients (Gr. A n = 8), the other of geriatric patients (Gr. B n = 8). Evaluation of EEG and CEEG was done by to experienced electroencephalographers separately. Interpretations of both methods were compared and found to correspond. In group A variations found in the baseline EEG were within normal limits and corresponded with those seen in the average population. In group B 67.5% of the examined EEG's showed variaions from normal. After intravenous premedication with Diazepam both groups of patients showed changes in the electrogrm as well as in the clinical condition. Changes in group B were more marked. Characteristic of EEG changes induced by Diazepam was a high increase of activity of beta-waves from 12-20 Hz and decrease of alpha-waves. These alterations were seen together with the clinical signs of psychical indifference and effects of sedation. A temporary activation of frequencies between 4-8 Hz was also found which indicates sleep.

Adult↗

[EEG-effects of atropine. Study on 16 patients (author's transl)].

Changes of EEG and CEEG have been studied in two groups of patients premedicated with 0,5 mg atropine. Study group A (n = 8) consisted of patients whose age ranged from 20 to 50 years, study group B (n = 8) of patients above 70 years. The observaton ranged from 15 to 60 min. In addition mental condition, blood pressure and pulsrate were registrated. The base line electroencephalogram of all patients was within the normal range. Atropine caused slight changes of power. Alpha-activity decreased whereas delta- and theta-activity increased. The changes were more pronounced in young patients. The behaviour of 14 patients did not change. Two patients showed slight side-effects. Correlations of changes in the electroencephalogram and clinical behaviour could not be verified. The pulse rate measurements showed an increase, without significance.

Adult↗

[EEG-effects of pethidine-promethazine. Study on 16 patients (author's transl)].

Changes of EEG and CEEG have been studied in two groups of patients premedicated with pethidine-promethazine (dosage: 50 mg/25 mg). The study group A consisted of patients whose age ranged from 20 to 50 years; in study group B the patients age was above 70 years. Continous EEG and CEEG observation ranged from 15 minutes to several hours in a few patients. Changes in clinical behaviour were recorded. Blood pressure - pulserate - measurements were taken at regular intervals. The base line electroencephalogram of thirteen patients was normal. One dialysis-patient of group A and two old patients of group B showed deviations from normal. Characteristic changes in the electroencephalogram after the tested premedication were a decline of alpha amplitude or in primarily abnormal electroencephalographic recordings a narrowing of the frequency band in higher parts, and additionally and increase of delta/theta-activity. These changes lasted several hours. In good correlation to these findings were the clinical effects of sedation and sleep. Side effects were not seen. Remarkable changes of blood pressure and pulserate were not observed.

Adult↗

[EEG effects of premedication with thalamonal. a clinical study on 16 patients (author's transl)].

Changes of EEG and cEEG have been studied in two groups of patients (n=16) premedicated with 2 ml Thalamonal iv. (dosage: 5 mg droperidol; 0.1 mg fentanyl). Study group A consisted of patients, whose age ranged from 20 to 50 years, in study group B the patients' ages were avove 70 years. EEG and cEEG observation time was 15 min in general; in a few cases on hour. Changes in clinical behaviour were registered; blood pressure and pulse-rate measurements were taken at regular intervals. The base line electroencephalogram of twelve patients was unremarkable. Four elder patients of group B showed deviations from normal. Characteristic changes in the electroencephalogram after the tested premedication were: a decent accentuation and a light shifting to lower frequency of alpha-activity; in addition a light increase of delta-frequency. In good correlation to these findings were the clinical effects of sedation and light sleep. Light side effects in behaviour were seen in one patient. The tested disage of Thalamonal i.v. lowered the blood pressure particularly in younger patients.

Adult↗

[EEG-effects of halothane. Studies on 50 patients (author's transl)].

Induction of anaesthesia with 1 vol% halothane N2O/O2 3:1 was electroencephalographically registrated in 50 patients between 20 and 80 years. Blood pressure - and pulse rate - measurements were taken at regular intervals. The clinical course of anaesthesia and changes in EEG corresponded. 4-5 min after the beginning of inhalation the first clinical and encephalographic signs were seen: The base-line-electroencephalogram changed characteristically. Weak rhythms disappeared; fast frequencies of 10-32 Hz developed accompanied by clinical excitation, and at the same time low waves of 2-4 (6) Hz increased and became dominant. Distinguishing EEG-features of deep anaesthesia: 15 min after the beginning of halothane inhalation. Here was flattening with high delta (theta) activity. Anaesthesia was lowered by intubation. EEG showed signs of alpha theta or increasing fast activity. In good correlation the blood pressure and pulse rate increased. Deviations from this general behaviour were recorded in patients in poor condition and with blood pressure levels below the need of cerebral blood flow demands.

Adult↗

Testicular volume and function in adolescence after breech delivery.

Testicular volume and pubertal development were investigated in 108 boys born by breech delivery aged 14 1/2 to 19 1/2 years. Mean testicular volume was slightly but not significantly lower than in a control group of the same age. Pubertal development was normal. One boy had unilateral and two boys bilateral testicular atrophy (one with azoospermia and one with oligospermia). In a control group of 135 boys delivered from vertex position ther were three cases with unilateral and none with bilateral testicular atrophy. In both groups all cases with unilateral testicular atrophy could be explained by postnatal testicular injury, whereas the two cases of bilateral atrophy in the group of breech delivered boys remained unexplained. They may have originated from local trauma during breech delivery. It is concluded that testicular atrophy as a complication of breech delivery is seen with a frequency of only 2% or less.

Adolescent↗

[Pre and postoperative EEG monitoring as illustrated in various routine anesthesia methods].

EEG monitoring was performed on 600 patients during anesthesia or postoperatively. Typical courses were evaluated. Examples of EEG dependence on the kind of anesthesia, the age of the patient, and individual sensitivity to the dosage of the anesthetic agent are given. These results may indicate that EEG monitoring is valuable in the clinical routine and in adjusting the dosage of anesthetics to the individual cerebral situation.

Adult↗

[Test methods for surgical hand disinfection (author's transl)].

As exemplified by a test preparation, methods for assessing the effect of hand disinfection on the resident flora are put up for discussion. The test of a method for hand disinfection must make allowance for conditions prevailing in practice. Accordingly, the following steps should be taken into consideration: A. Single use 1. Immediate disinfecting effect 2. Duration of the disinfecting effect B. Repeated use 3. Course of the initial colony count 4. Immediate disinfecting effect 5. Behaviour of colony count after interruption of the disinfecting method applied. For the purpose of comparing the total count, as with all other disinfecting methods, the colony count must be determined by fractional collection methods; to this end, Traub's procedure may be modified, possibly using the plastic bag method described by Gaschen. A careful statistical evaluation with appropriate transformation of the results is indispensable.

Bacteria↗