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Biomedical subjects

U Meier

Publications and source records attributed to U Meier.

At least 19 recordsLinked to original sources

The traumatic dural sinus injury--a clinical study.

In a period of 13 years 978 cases of severe head injuries were operated on in our clinic. An analysis of the medical reports includes injuries of the superficial dural sinus (39 cases = 4%): among these injuries of the anterior and central part of the superior sagittal sinus (66 per cent), injuries of the transverse sinus (18 per cent), injuries of the posterior part of the superior sagittal sinus (8 per cent), and combined injuries of different dural sinuses (8 per cent). Clinical data, i.e. the causes of accident, radiological examination results, intracranial lesions, operation techniques and outcome are analysed and discussed. The analysis of cases with dural sinus injuries shows a high mortality rate (total mortality rate: 16 patients = 41%; intra-operative mortality rate: 8 patients = 20%).

Adolescent

[Rupture of the Achilles tendon--fibrin gluing or suture?].

The rise of recreational sports activities and the incidence of ruptures of the Achilles tendons has increased simultaneously. Recently the use of fibrin sealing for surgical therapy of ruptured Achilles tendons has emerged as an alternative technique. Between 1982 and 1989 62 consecutive patients were operated for unilateral Achilles tendon rupture. Following causes for ruptures are known: 36 indirect traumas in sport (74%), 9 direct blunt injuries at occupational work (18%), 3 traffic-accidents (11%) and 1 rupture after operation of a Haglund exostosis. 25 patients (56%) were treated by suture technique and 20 patients (44%) with fibrin sealant. The mean long term follow-up of 49 months is known of 49 patients. There were 3 (12%) postoperative infections in the suture group and none in the fibrin group. After suturing the Achilles tendon 3 (12%) reruptures occurred 8-10 weeks after tendon repair and 1 (5%) rerupture after fibrin sealing. All reruptures are caused by a new adequate trauma. The time of return to social and recreational activities was 9 months in the suture group and 7 months in the fibrin group. The functional and cosmetic results after use of fibrin was significant better, and the long-term results were very satisfactory. We prefer fibrin sealing for the treatment of acute ruptures of Achilles tendons.

Achilles Tendon

[Aspects of rehabilitation after early stabilization of complex injury of the cervical spine].

Within the scope of catamnestic investigation and a follow-up examination 170 fractures of the cervical spinal cord, operated in a period of 8 years, were explored. Dependent on the neurological starting point the length of stay in hospital, the time of temporary disablement and the results of social rehabilitation were evaluated. The examination results are appraised.

Activities of Daily Living

[Postoperative results following severe craniocerebral trauma].

918 patients were operated because a severe head injury in our Neurotraumatological Clinic during a period of 12 years. 733 patients (80 per cent) could been evaluated as well with regard to the Glasgow Coma Scale and the Glasgow Outcome Scale as analysed in four diagnose groups corresponding to the period of live. Patients with epidural haematoma and open head injuries showed a better forecast than patients with acute subdural haematoma. Those with contusion of the brain and less than 8 points in the Glasgow Coma Scale or those in a higher age had a bad prognosis.

Adolescent

[Results of the surgical management of frontobasal injuries].

The author reports about 183 patients with frontobasal injuries. 50 per cent of them were operated immediately because open injuries or intracranial complications. The other half was operated in an interval of 5 to 10 days after injury. The localisation of the frontobasal lesion, clinical results according to the Glasgow Coma Scale and Glasgow Outcome Scale as well as the operation methods are demonstrated and discussed. The operative closure of the dura failure with an unipedicled periosteal flaps ensures good results in the most cases.

Brain Injuries

[Typical CT findings with the intrathecal infusion test in post-traumatic disorders of cerebrospinal fluid dynamics].

Simultaneous computer tomographic and cerebrospinal fluid dynamics examinations in patients with high-pressure hydrocephalus, normal pressure hydrocephalus and cerebral atrophic processes are presented and discussed. Exclusive CT and MR examinations do not allow a differentiation of patients with normal pressure hydrocephalus and patients with cerebral atrophy. In the simultaneous examinations the morphological substrate during the intrathecal infusion test is represented.

Adult

[Indications for the intrathecal infusion test in disorders of cerebrospinal fluid dynamics].

Indications for and results of the intrathecal infusion test including 50 patients with chronic disturbances of the circulation of the cerebrospinal fluid are presented and discussed. The computer-aided infusion test permits in 93 per cent a reliable differentiation between patients with a normal-pressure hydrocephalus and those with cerebro-atrophic processes. Functional checking of the valve systems is a further indication for the intrathecal infusion test. In patients with a classical pressure hydrocephalus or subdural hygromas, however, we do not see an indication for this invasive examination procedure.

Adolescent

[Axial osteosynthesis of dens axis fracture as a routine procedure in neurotraumatology. Diagnosis--Surgical-technique--Complications--Follow-up].

A survey on 34 cases of odontoid process fractures treated by means of axial osteosynthesis since 1981. In cases of acute fractures rate of bony consolidation was 100%, in cases of pseudoarthrosis 50%. 6 complications until the first 20 weeks were successfully treated. No later complications. Removal of implanted material is usually not necessary. Operative treatment of non union by means of bony grafting, axial osteosynthesis and atlanto-axial arthrodesis seems to be helpful. Investigations for the best implantation model must be continued.

Adolescent

[Results of surgical treatment of 170 injuries of the middle and lower cervical spine].

The article presents the results of examination of 170 patients with a cervical spine injury, who had been operated by ventral interbody fusion. It presents operative procedures and discusses the results concerning to neurological deficit before treatment. Cloward-Crock's and Bailey-Badgley's technique together with anterior plate fixation yields immediate stabilization and provides the best functional outcome.

Adolescent

[The need for spongiosa grafting in thoracolumbar vertebral body fractures].

Report on examination of 31 patients with fractures of spine in thoracolumbar region. All patients were treated by external fixation without accomplishing a plastic of spongiosa. The permanent SI-Index after operation is coming to 0.85. The outcome by use of external fixation is attesting our opinion, that with this method a plastic of spongiosa isn't necessary.

Bone Transplantation

[Experimental studies of chemonucleolysis with aprotinin].

We have attend operatively exstirpated tissue of intervertebral disks to solution with 250.000 I. E. and 500.000 I.E. aprotinin. After preparation and colouring of the tissue we examinate by microscope. We couldn't find out neither a macroscopic nor microscopic evident effect of chemonucleolysis of aprotinin. Our opinion is, that an application of aprotinin to reduction of intradiscal pressure or to chemonucleolysis isn't effectively.

Aprotinin

[The classification of neurons in the corpus geniculatum laterale pars ventralis of the albino rat: a Golgi-Kopsch study].

Neurons in the ventral lateral geniculate nucleus of 120 rats of a wistar strain were investigated with the Golgi Kopsch technique. Various features, such as size of neurons, their dendritic fine structure and their localization inside the nucleus were used to find new aspects for the classification of vLGN neurons except geniculo tectal relay neurons (GTR neurons). The results of our detailed investigation are in accordance with the classification given by Brauer et al. (1984). The dendrites show different morphological surface specializations, as there are smooth and varicose dendrites besides the spiny ones. Medium-sized neurons are most variable in their dendritic structure. It can be assumed that they represent a heterogenous group. The density of spines in the neurons investigated is much lower than in GTR neurons.

Animals

[Fixateur externe as a definitive treatment method of unstable thoracolumbar spinal fractures in emergency conditions--technical modification and clinical experiences].

A survey on 31 injuries of thoracolumbar spine, 27 were accompanied with neurological deficiency. Treatment was exclusively by means of percutan attached f.e. until bony consolidation. An average treatment time of 152 days took place. Mean rate of correction was about 0.24 (Beck's SI-Index). The former applied frame construction was substituted by self developed spindle fixateur system, adapted to the requirements of traumatology of the spine in emergency situations.

Adolescent

[Dorsal ganglion of the wrist joint: a trivial, minor surgery intervention?].

A small operation which is thought to be trivial with a recurrence rate of 30 to 40 percent. The dorsal ganglion of the hand arises from the typical predilection site in the dorsal portion of the scapholunate ligament. By excising the capsular attachments over the scapholunate ligament we can significantly reduce the recurrence rate to only a few percent. But the absence of recurrence doesn't guarantee for certain that the patients are painfree. In spite of the operation one third of the patients complain of persisting pain which is often due to an irritation of the posterior interosseous nerve (PIN) by the ganglion. A selective dissection and resection of the PIN proximal to the radiocarpal unit as a partial dorsal wrist denervation is proposed. This shows that the indication for the operation must be evaluated thoroughly.

Humans

[Computerized tomography and electroencephalography findings in post-traumatic brain edema].

The reduction in size of the ventricular areas in the computer tomogram as a morphological substrate of a generalised cerebral edema in 43 patients correlated better with the vigilance than with the EEG findings. This fact as well as the representation possibility of additional intracranial haemorrhages favour the computer tomography in the posttraumatic acute phase as compared to the electroencephalography, which should be employed in the subacute phase.

Adolescent

[The relative importance of the brain stem acoustic evoked potential (BAEP) in patients with brain stem tumors].

The brain stem acoustic evoked potential is a non-invasive procedure at the disposal of neurological diagnostics that permits to obtain information about the functional condition of the brain stem. As regards the question of the topodiagnostic possibilities of this examination method in patients with brain stem tumours the BAEP parameters were compared with the clinical symptoms existing at the time of the examination as well as with computer tomographic findings. There is a good agreement of the severity of the clinical symptoms and the distinction of the BAEP changes. In case of unilateral BAEP changes or BAEP changes with a pronounced accentuation on one side indications with respect to the lateral localisation of the brain stem tumour in connection with the clinical findings can be derived. An exact topodiagnosis of brain stem tumours is exclusively possible by the correlation of clinical symptoms, results of picture-yielding examination methods and BAEP examination.

Adolescent