Biomedical subjects

U Moritz

Publications and source records attributed to U Moritz.

At least 37 records · Page 2Linked to original sources

PubMed1990

Dynamic versus static training in patients with rheumatoid arthritis.

Sixty-seven patients with classical or definite rheumatoid arthritis (RA) were studied concerning the effects of standardized physical training on muscle function in the lower extremities. The patients were randomly assigned to four different training groups and were given 6 weeks of training supervised by a physiotherapist at a health care centre. The groups differed according to type (dynamic or static) and extent (12 or 4 times) of training. During this training period as well as for an additional 3 months, the patients carried out programs of exercise at home (either dynamic or static). A significantly greater increase in function during the 6-week period as regards muscle strength, endurance, aerobic capacity, and functional ability was found for the dynamic as compared with the static groups. The findings at follow-up 3 months later were similar. The effectiveness of the programs did not vary with the extent of training. In conclusion, in RA patients, dynamic training gives a greater increase in physical capacity than does static training.

Activities of Daily Living↗

PubMed1990

Disability in anterior cruciate ligament insufficiency. An analysis of 19 untreated patients.

We analyzed the knee function in 19 consecutive patients with chronic instability after an anterior cruciate ligament rupture. Muscle strength, standing balance, activity level, functional knee score, and a performance test were evaluated. Reduced quadriceps muscle strength compared with the noninjured limb was associated with reduced performance as measured by the one-leg hop test and the Lysholm knee score. No weakness in the hamstrings was found. The patients had impaired standing balance with increased body sway in the frontal plane when standing on both the injured and noninjured limb.

Adolescent↗

PubMed1990

Cervical pain and discomfort among dentists. Epidemiological, clinical and therapeutic aspects. Part 1. A survey of pain and discomfort.

The aim of the investigation was to study the frequency of pain, ache and discomfort in the musculoskeletal system among dentists, above all concerning headache, cervical and shoulder pain and further, to find possible correlations between these symptoms and various working positions and different working actions. A questionnaire was answered by 359 dentists (90.8%). Of those who answered the questionnaire 72% had pain and discomfort from either the neck, shoulders or headaches. Only 60 dentists had no pain or discomfort. Concerning the male dentists, the investigation revealed that younger dentists had pain and discomfort in the neck, shoulders and headaches to a greater extent than the older dentists. Younger female dentists had a significantly higher frequency of pain and discomfort in the neck and headaches than older colleagues. The results showed that dentist who positioned the patient carefully so that a direct view gained had a significantly lower frequency of headaches. Of the 359 dentists 55% mostly used the mirror to facilitate a direct view. From the answers it was clear that those dentists who did not have discomfort in the upper locomotor system used the mirror more often than those who did suffer discomfort.

Adult↗

PubMed1989

Diabetes mellitus and disability pension. A descriptive study of all diabetic subjects granted disability pension in Sweden in 1980.

Disability documents of all diabetic persons (n = 1,707) granted a disability pension in Sweden during 1980 were studied. The following factors were analysed: age, sex, civil status, profession, unemployment, being a housewife, immigration status, form for disability pension application, duration of diabetes, type of treatment, presence of classical late complications and age at onset of diabetes, obesity and alcohol problems. Functional handicaps and symptoms related to a clinically advanced diabetes mellitus could be regarded as the basis for the decision to grant a disability pension to 20-25% of the pensioners. For the remaining 75-80% neither the diabetic state nor its late complications could be held responsible for reduced work capacity. Rather, symptoms like angina pectoris and rheumatic symptoms and many other factors such as obesity, alcohol problems, being an immigrant, or being unemployed influenced the decision to grant a disability pension.

Adolescent↗

PubMed1989

Joint capsular stiffness in knee arthritis. Relationship to intraarticular volume, hydrostatic pressures, and extensor muscle function.

Increased intraarticular hydrostatic pressure (Pia) may inhibit juxtaarticular muscle function, obstruct blood supply to joint structures and promote anoxic joint destruction in chronic arthritis. Joint capsular stiffness together with synovial fluid volume determines Pia at rest. Seventeen knee joints with effusive arthritis and different degrees of radiological cartilage involvement in 13 patients with chronic arthritis were examined. Since capsular elastance was difficult to standardize, we introduce a measure of joint capsular stiffness where the intraarticular volume yielding a pressure of 50 mm Hg (V50) is used. After normalization of injected volumes according to the V50, pressure volume curves became similar. Intraarticular hydrostatic pressure and maximal voluntary isometric extensor torque were measured simultaneously, while altering the intraarticular fluid volume in 9 knee joints. In 5 of these, quantified electromyography (EMG) of the vastus medialis and lateralis portion of the quadriceps muscle was also monitored. Progressive inhibition of extensor torque and EMG was found as the intraarticular pressure volume was increased in both intact and destroyed joints. No difference in inhibition was found for the 2 portions of quadriceps muscle tested. Increased intraarticular hydrostatic pressure Pia levels between 200 and 1150 mm Hg were observed during maximal voluntary activation of extensor muscles. The reproducibility was good for all variables studied. In a few instances evidence of intraarticular compartmentalization was found at low volumes. We conclude that the V50 is a convenient expression of capsular stiffness. Furthermore, increasing Pia caused by joint effusion inhibits knee extensor muscle function and impairs synovial blood flow. Awareness of these relations will facilitate more rational therapeutic approaches in chronic arthritis.

Arthritis↗

PubMed1987

The clinical picture of the painful diabetic shoulder--natural history, social consequences and analysis of concomitant hand syndrome.

Sixty diabetic patients with shoulder pain were followed in order to trace the natural history of the disease. The triad of painful shoulder, hand syndrome and restricted hip joint mobility was strongly correlated to the duration of diabetes and retinopathy. Painful shoulder with restricted mobility (58%) and tendinitis (28%) predominated. Hand syndrome was found in 62% and restricted hip joint mobility in 42%. Ninety percent of painful shoulders with restricted mobility had difficulties in the activities of daily living in the acute phase. There was functional limitation of shoulder mobility in 17% of painful shoulders with restricted mobility at the end of the study. The duration of diabetes and the duration of shoulder symptoms were correlated. In 25%, working capacity was affected by the painful shoulder. A serious risk of developing shoulder symptoms persisting for more than 2 years was associated with insulin treatment, diabetes lasting more than 10 years, proliferative retinopathy and painful shoulder with restricted mobility.

Diabetes Complications↗

PubMed1986

Thermogenesis in human skeletal muscle as measured by direct microcalorimetry and muscle contractile performance during beta-adrenoceptor blockade.

The influence of beta-adrenoceptor-blockade on skeletal muscle was studied in ten healthy males with propranolol, atenolol and pindolol randomly given for 8 days each in a cross-over double blind test. After 7 days on each drug, muscle function was tested by an isokinetic dynamometer. Thermogenesis in biopsy samples taken from vastus lateralis muscle after a low grade exercise was studied after 8 days on each drug by direct calorimetry with a perfusion microcalorimeter. Before drug administration, a median heat production rate of 0.67 mW/g of muscle was measured. This value was significantly reduced by 25% during propranolol, but no significant change was found during atenolol or pindolol administration. Peak torque decline during isokinetic endurance test changed significantly in knee flexor but not in extensor muscles, from 15% to 27% after propranolol and from 15% to 23% after pindolol. Maximum dynamic strength was unaltered. Our data suggest that blockade of sympathetic beta 2-receptors decreases thermogenesis in human skeletal muscle and impairs isokinetic endurance.

Adolescent↗

PubMed1986

The painful diabetic shoulder.

Different types of shoulder affection were studied in 62 diabetic patients with shoulder pain. Three groups of shoulder joint disorder were found: painful shoulder with restricted mobility (62%), tendinitis without mobility restriction (27%), and a small group with mixed diagnoses. Sixty per cent had hand symptoms and 38% had restricted mobility of their hip joints. High frequencies of retinopathy and neuropathy were found. Affection of the shoulder joint was seen with almost the same frequency in insulin-dependent as in non-insulin-dependent patients, but after a shorter duration of diabetes in the latter. A group of patients with the triad shoulder pain, hand symptoms and restricted mobility of the hip joints had a significantly higher frequency of proliferative retinopathy than patients with shoulder pain only. The long duration of diabetes, the high frequency of insulin treatment and classical late complications indicate that diabetic patients with painful shoulder and restricted mobility are suffering from clinically advanced diabetes mellitus.

Adult↗

PubMed1985

L-carnitine and haemodialysis: double blind study on muscle function and metabolism and peripheral nerve function.

Twenty-eight haemodialysis patients were randomized to L-carnitine, 2 g i.v. three times a week, and saline over a 6-week period. No obvious deficiency of carnitine was found in vastus lateralis with a median value of 12.9 mmol/kg dry weight; range 6.2-21.4. Female patients had lower total plasma carnitine compared to female controls, p less than 0.002, whereas no decrease was found in males. No relationship was found between muscle and total plasma carnitine. After carnitine administration the muscle carnitine level increased about 60%, p less than 0.01, and the total plasma carnitine level more than tenfold, whereas the initially high degree of acylation decreased, p less than 0.02. Maximum dynamic muscular strength was reduced with a mean value of 44% compared with healthy controls. Total metabolic activity of isolated skeletal muscle fibres, measured as heat production with a new technique using a perfusion microcalorimeter, showed a median value of 0.40 mW/g, 25% lower than normal, p less than 0.02. Carnitine administration had no effect on several different tests of muscular function. Neurophysiologically, discrete improvements in the temperature responses were recorded, but no changes in sensory and motor nerve conduction velocities or in vibration thresholds were noted. No symptomatic improvement was observed even in patients with the lowest carnitine levels prior to treatment. Our data do not support the hypothesis that carnitine deficiency contributes to muscle and nerve dysfunction in patients on chronic haemodialysis.

Adult↗

PubMed1985

Intra-abdominal pressure and trunk muscle activity during lifting. III. Effect of abdominal muscle training in chronic low-back patients.

Isometric training of the abdominal muscles is often recommended in programs of primary or secondary prevention for low-back pain. In this study 20 male workers with 2-18 years' history (average 5 1/2 years) of low-back pain without sciatica went through intense isometric abdominal muscle training for 5 weeks. Before and after training the subjects had trunk flexion and extension strength tests and a series of standardized lifts. The intraabdominal pressure (IAP) and the EMG activity of the oblique abdominal muscles, and of the erector spinae muscle were recorded. It was found that: the strength of the abdominal muscles increased; the increased strength was correlated to an improved recruitment of motor units in the oblique abdominal muscles; the EMG activity of the oblique abdominal muscles when lifting decreased after training, i.e. the acquired ability to recruit more motor units was not made use of; the IAP at lifting was generally not affected. A better knowledge of the mechanisms responsible for the IAP in different situations is needed to support advice on training or other prevention.

Abdomen↗

PubMed1985

Intra-abdominal pressure and trunk muscle activity during lifting. IV. The causal factors of the intra-abdominal pressure rise.

The intra-abdominal pressure (IAP) has been regarded as important for stabilization and relief of the lumbar spine when exposed to heavy loads, such as when lifting. Previous trials, however, have failed to increase the IAP by abdominal muscle training. Twenty healthy subjects, 20 low-back patients and 10 weight-lifters, were tested with various breathing techniques in order to elucidate the causal factors of the IAP rise during lifting and the effects respiration. Those with high IAP and low IAP as well as those with great variations in IAP underwent an extended program. The intra-abdominal and intrathoracic pressures and the EMG of the oblique abdominal, the erector spinae and--in some cases--the puborectalis muscles, were recorded. The transdiaphragmatic pressure was calculated both during lifting and during the Mueller manoeuvre. The IAP rise during lifting seems to be correlated to a good coordination between the muscles surrounding the abdominal cavity. Of these, the diaphragm seems to be the most important for the IAP level. Closure of the glottis seems to help the diaphragm to maintain the IAP rise, otherwise the respiration type seems to be less important for the IAP during lifting.

Abdomen↗

PubMed1985

Intra-abdominal pressure and trunk muscle activity during lifting. II. Chronic low-back patients.

The aim of this study was to compare trunk muscle strength and intra-abdominal pressure during lifting in low-back patients and in healthy controls. Twenty male workers with 2-18 year history (median 5.5 years) of low-back pain went through strength tests of trunk flexion and extension and a series of standardized lifts. The intra-abdominal pressure (IAP) and the EMG activity of the oblique abdominal muscles and of the erector spinae muscles were recorded. The results were compared with those in 20 healthy men exposed to similar loads at work and at leisure. The low-back patients had reduced abdominal muscle strength (-25%) compared with the healthy controls. The IAP during lifting was the same in the two groups despite the difference in abdominal muscle strength. The trunk extension strength was the same in the two groups. The oblique abdominal muscles were only moderately activated during lifting (5-15% of maximum activity with 25 kg) both in low-back patients and in healthy controls. The erector spinae muscle was strongly activated during lifting (40-60% of maximum activity with 25 kg) both in low-back patients and in healthy controls. During backlifting the duration of erector spinae activity varied. Back patients had extended activity compared with the healthy controls. Stiffness seemed to affect the duration of activity in both groups. The oblique abdominal muscles seem to be of no decisive importance to the IAP.

Abdomen↗

PubMed1979

Evaluation of manipulation and other manual therapy. Criteria for measuring the effect of treatment.

In order to evaluate manipulation and other methods of manual therapy, the literature was reviewed. It was found that the number of publications based on scientific criteria is rather limited. However, with certain reservations it can be concluded that manipulation of the lumbar spine might have an immediate, short-time effect on low back pain in a limited number of patients. The criteria for selection, however, cannot be defined on the basis of the available material. Manipulation has no superior long-term effect as compared to other methods of treatment. The effect of specific, non-manipulative mobilization of the cervical and lumbar spine needs further elucidation. Manual therapy in decreased mobility of the extremity joints has received support from control studies.

Back Pain↗

PubMed1979