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Biomedical subjects

U Morr-Strathmann

Publications and source records attributed to U Morr-Strathmann.

10 recordsLinked to original sources

Influence of inhalation anaesthetics on bronchomotor tone--animal experiments on vago-vagal reflex bronchoconstriction.

Animal experiments showed that the inhalation anaesthetic agents enflurane and halothane caused neither a direct increase in bronchial resistance nor an indirectly mediated increase in the susceptibility of the bronchial system to acetylcholine. There are, therefore, no contraindications to the clinical use of enflurane and halothane in cases of obstructive airway diseases, nor does the use of these agents present an increased risk for these patients.

Anesthesia, Inhalation↗

[Effects of ethrane and halothane on compliance and resistance (author's transl)].

In young patients with healthy lungs, the effects of ethrane and halothane on compliance and resistance have been investigated. With the use of ethrane we found a dose-dependent decrease in compliance, but this decrease was statistically assured only at relatively high inhalation concentrations. The resistance of the respiratory passages remained virtually unchanged. Similar changes in compliance and resistance have also been observed with the use of halothane. The decrease in compliance induced by both anesthetic agents may be due either to interference with the surface tension of the alveolar wall, or to transitory changes in the fluid content of the pulmonary parenchyma. For the practical use of ethrane and halothane no significant differences appear to exist on the basis of their effects on compliance and resistance.

Adult↗

[Haemodynamic effects during hypotension with sodium nitroprusside neurosurgery (author's transl)].

Haemodynamic effects during hypotension with sodium nitroprusside in the surgery of cerebral aneurysms were studied in 16 patients. Sodium Nitroprusside caused arterial hypotension by a direct vascular musculotropic effect and it was found to reduce peripheral vasculare resistance, and to lower the bloodpressure in the right atrium and pulmonary arteries. Stroke volume decreased in the presence of tachycardia while there was no change in cardiac output. Its evanescent action and easy regulation make sodium nitroprusside suitable for controlled hypotension during cerebral surgery, especially since there are no negative haemodynamic effects.

Adolescent↗

[Haemodynamic studies during anaesthesia with etomidate and neflurance in ge-iatric patients].

The influence of combined anaesthesia with enflurance and etomidate on the haemodynamics of the main and pulmonary vasculary systems was studied in geriatric patients. The results showed a decrease in cardiac output with consecutiv fall of the mean arterial pressure and a significant increase in mean pulmonary arterial pressure. According to our experiences there are less complications in cardiac andpulmonary system, when enflurance is combined with etomidate.

Age Factors↗

[The influence of enflurane on the haemodynamics in the pulmonary vasculary system (author's transl)].

The influence of enflurane on the haemodynamics of the main and pulmonary vasculary system was studied in young healthy patients. The results showed no influence in heart frequency and mean arterial pressure, a slight fall in certain output and a significant increase in mean pulmonary arterial pressure. There is no certain explanation for the pathophysiological mechanism in pulmonary vasculary system caused by enflurane. According to our opinion these results are to discuss as a cause of a decrease of left ventricular work and a regulative vasoconstriction in the pulmonary vasculary system.

Adult↗

[Serratia marcescens infection in intensive care units (author's transl)].

The increased incidence of Serratia marcescens infection at the intensive care unit of the Department of Anaesthetics, General Hospital Altona, was investigated. The properties of this microorganism are described and its role in cross infections is discussed. The frequent occurrence of Serratia marcescens in mixed infections and its tendency to grow on tissue surfaces are pointed out. The presence of Serratia marcescens was demonstrated in 23 of 107 patients treated in the intensive care unit; an infection with Serratia was established in 13 of the 23 cases. Four patients died. As vital functions were severely impaired in these cases death could not be attributed solely to the Serratia infection. Preventive and therapeutic measures are reviewed.

Adolescent↗