[Immunological aspects of primary carcinoma of the liver].
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Biomedical subjects
Publications and source records attributed to U Palazzo.
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The Hepanostika micro-ELISA System was used, with some modifications, for the indirect detection of anti-HBs antibodies. The proposed method is rapid, easy to perform, reproducible, and specific and approaches radioimmunoassay in sensitivity (92.6% agreement). An advantage over radioimmunoassay is the possibility of revealing antibodies in sera containing immune complexes, but this will require further investigation.
Scanning of 31 cirrhosis and 25 cancer-cirrhosis patients has been carried out using 198Au and then 67Ga. In 23/25 cancer-cirrhotic patients 67Ga was picked up in areas cold to 198Au (8% false negatives); such behaviour was not observed in any of the 31 cirrhotics (no false positive).
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To expand the donor pool, clinicians are continually modifying criteria to accept organs, particularly those in the so-called expanded or marginal donor pool. The concept and definition of a marginal donors continues to evolve. The impact of their use is the result of a combination of donor and recipient factors. Most clinicians accept steatosis above 30%, donor age over 60 years, prolonged ischemia time, prolonged intensive care unit stay, hypernatremia, previous cardiac arrest, prolonged episodes of hypotension, large use of inotrope drugs, and elevated liver function tests as criteria for designation of a marginal organ. In June 2003, we started to use marginal donors each year tripling the number of transplants per year at our center.
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An increase in dental decay of 48.89% over controls fed with a cariogenic diet was noted when gastric mucoprotein and vitamin B12 were administered to rats receiving a standard diet.
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The Author considers the necessary requisites for the complete denture's stability during masticatory function. This is due to the following anatomic and functional factors: a) Support tissues' morphology. b) Morpho-functional characteristics of the prosthetic tooth: unitary nupolivalent function in the different occlusal sectors. c) Linear arrangement of the teeth with unitary function along the "structural sagittal axis" or "central axis of dinamic and muscolar stabilization" of the mandible. d) Teeth's arrangement in the neutral or muscolar equilibration zone. e) Interalveolar axis' verticality of the teeth with unitary grinding function.
There is a necessary correlation between the Monson's curve, due to the mandibular kinematics, and the interalveolar axis' inclination in the different occlusal areas with unitary function. In the triturating area the verticality of the interalveolar axis is necessary for the stability of the cusp-fossa relationship in centric occlusion and for the stability of the prothesis during mastication. The Author shows the occlusal morphology and the arrangement of the prosthetic teeth in the different skeletal classes in relation to functional interalveolar strength's direction.
The author analyzes the fundamental parameters of the complete denture; stability occlusal in the eccentric mandibular movements. They are: a) Correlation between condylar and incisal guide and occlusal morphology of the dental-arches. b) Presence of interincisive and intercanine functional free space.
Remembering at the common aim for every endodontic treatment, the authors underline that is basal to clean and shape the root canal. The authors describe technical and anatomical handicaps existing in this stage and discriminate between traditional instruments and endosonic instruments. They also remember the advantages of ultrasonic joined with mechanical smoothing of the canal; after they make clear some concepts of wave physics to clarify the terms utilized in this study. Moreover they discriminate endosonic sets in sonic and ultrasonic devices. The authors conclude their study thinking that the endosonic way in endodontics is the synthesis of physical, chemical and biological effects.
The authors describe the differential characteristics between sonic and ultrasonic endodontic devices: the former type is pneumatic and uses the air coning from the odontoiatric chair that gives to the endodontic instrument only a lateral way of swinging. The latter type changes the ultrasonic activity coming from piezoeletric phenomena into swinging mechanical energy (operating at 25 KHz). The authors specify the characteristics of endodontic instruments and explain their operating ways, demonstrating that reaming by endosonic instruments increases effects of hypochlorite. They also describe the operating train, pausing on the opportunity that the root canal should be manually probed, measured and reamed up to a diameter that gives sufficient space to the file vibration. They conclude listing the advantages that gives the correct use of sonic and ultrasonic devices; they also augur that with their use endodontics could have a greater diffusion.
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