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Biomedical subjects

U Parekh

Publications and source records attributed to U Parekh.

7 recordsLinked to original sources
PubMed1999

Effect of increased fluid intake on stool output in normal healthy volunteers.

Constipation is a common condition affecting millions of people throughout the world. The present study aimed to determine the effect of extra fluid intake, as recommended by many primary care physicians and gastroenterologists, on the actual stool output in normal healthy volunteers. We recruited 15 healthy volunteers (aged 23-46 years, mean 30.1) without any significant history of diarrhea or constipation to participate in our study. Nine subjects underwent extra intake of isotonic fluids (Gatorade), whereas the remainder received extra free water over their baseline. During period I (3 days), baseline diet and fluid intake were determined by a registered dietitian. During periods II and III (2 days each), the volunteers in each group increased their fluid intake by 1 and 2 l of isotonic (Gatorade) and hypotonic solution (water), respectively. Period IV (2 days) completed the study with the volunteers returning to their baseline fluid intake. Urine and stool outputs were measured in these volunteers. Additional increase in fluid intake (isotonic or free water) did not result in a significant change in stool output. However, there was a significant increase in urine output (P < 0.05). Despite common medical advice to consume extra fluid for constipation, our results indicate that extra fluid intake in normal healthy volunteers did not produce a significant increase in stool output.

Adult↗
PubMedDate not supplied

Spontaneous rupture of the liver during pregnancy.

Spontaneous rupture of the liver, a rare but grave complication of pregnancy merits attention of an obstetrician. It is important to stress that proper antenatal care, prompt hospitalization with effective treatment at first alarming sign of preeclampsia and early induction of labour when medically indicated may prevent such a grave complication. The aim of this paper is to promote earlier diagnosis with massive fluid and blood replacement in order to decrease the mortality. It also forms the research bases for liver function tests in all those patients with essential hypertension or persistent toxaemia. The literature is reviewed briefly.

Adult↗
PubMedDate not supplied

Triplet pregnancy in Lusaka.

A series of 8 triplet sets during the year 1980 at the University Teaching Hospital, Lusaka, has been analysed. The incidence was 1:2980 hospital deliveries. Age or parity of the mother did not appear to have any influence on foetal survival, in contrast to the birth weight and foetal presentation at the time of delivery. First triplet baby seemed to have a better chance of survival as compared to second and third triplet babies. There was prepondence of female babies. The corrected perinatal mortality was 273/1000 live births which is significantly high.

Adult↗